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Vernix Caseo Granulomatous Meningitis (Vernicomyelia)

Published online by Cambridge University Press:  18 September 2015

Rajiv Midha  and
Laurence E. Becker
Rajiv Midha
Affiliation:
Division of Neuropathology, Department of Pathology, the University of Toronto, and The Hospital for Sick Children, Toronto
Laurence E. Becker*
Affiliation:
Division of Neuropathology, Department of Pathology, the University of Toronto, and The Hospital for Sick Children, Toronto
*
Department of Pathology (Neuropathology), The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
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Abstract:

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An apneic and tetraplegic infant with an open lumbosacral myelomeningocele and an Arnold-Chiari malformation is reviewed. An exuberant chronic aseptic meningitis with foreign body giant cells and immunoreactive keratin was present around the spinal cord and brainstem. This paper discusses the recognition and role of granulomatous meningitis in the clinical course and in the pathogenesis of the unusual cerebellar abnormalities found in this infant.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 18 , Issue 1 , February 1991 , pp. 63 - 65
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

References

1.Jacobs, EB, Landing, BH, Thomas, W Jr.Vernicomyelia. Its bearing on theories of genesis of the Arnold-Chiari complex. Am J Pathol 1961; 39: 345–353.Google ScholarPubMed
2.Correa-Restrepo, A, Robertson, C, Rozdilsky, B.Vernix caseosa meningitis and laryngeal stridor in an infant with myelomeningocele. Case report. J Neurosurg 1975; 42: 718–722.CrossRefGoogle Scholar
3.Agamanolis, DP, Hite, SH, Piatt, MS.Arnold-Chiari malformation: Contamination of ventricular and subarachnoid spaces by amniotic sac contents (Abstract). Canadian Association Neuropathologists meeting, Ottawa, Canada, 1984.Google Scholar
4.Copoletta, JM, Wolbach, SB.Body length and organ weights of infants and children. A study of the body length and normal weights of the more important vital organs of the body between birth and twelve years of age. Am J Pathol 1933; 9: 55–70.Google Scholar
5.Friede, RL.Forms of hindbrain crowding, including the Arnold-Chiari malformation. In: Friede, RL, ed. Developmental Neuropathology Berlin: Springer-Verlag 1989; 2: 263–276.CrossRefGoogle Scholar
6.Decker, RE, Gross, SW.Intraspinal dermoid tumor presenting as chemical meningitis. Report of a case without dermal sinus. J Neurosurg 1967; 27: 60–62.CrossRefGoogle ScholarPubMed
7.Shimoji, T, Shinohara, A, Shimizu, A, et al. Rathke cleft cysts. Surg Neurol 1984; 21: 295–310.CrossRefGoogle ScholarPubMed
8.Cantu, RC, Wright, RL.Aseptic meningitis syndrome with cauda equina epidermoid tumor. J Pediatr 1968; 73: 114–116.CrossRefGoogle ScholarPubMed
9.Schwartz, JF, Balentine, JD.Recurrent meningitis due to an intracranial epidermoid. Neurology 1978; 28: 124–129.CrossRefGoogle Scholar
10.Tomlinson, BE, Walton, JN.Granulomatous meningitis and diffuse parenchymatous degeneration of the nervous system due to an intracranial epidermoid tumor. J Neurol Neurosurg Psychiatry 1967; 30: 341–348.CrossRefGoogle Scholar
11.Horoupian, DS, Wisniewski, HM, Gamble, R, et al. Aqueduct gliosis caused by keratin and cholesterol in a case of craniopharyngioma. Can J Neurol Sci 1974; 1: 185–188.CrossRefGoogle Scholar
12.Dickson, DW, Neumann, PE, Horoupian, DS.Immunoreactive keratin with foreign body reaction in anencephaly. Acta Neuropathol (Berl) 1985; 67: 326–328.CrossRefGoogle ScholarPubMed