Hostname: page-component-8448b6f56d-wq2xx Total loading time: 0 Render date: 2024-04-25T04:07:01.868Z Has data issue: false hasContentIssue false
  • English
  • Français

Iron - Too Much of a Good Thing

Published online by Cambridge University Press:  02 December 2014

Mandar S. Jog  and
Derek B. Debicki
Mandar S. Jog
Affiliation:
University of Western Ontario London, Ontario, Canada
Derek B. Debicki
Affiliation:
University of Western Ontario London, Ontario, Canada
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Canadian Journal of Neurological Sciences , Volume 39 , Issue 3 , May 2012 , pp. 263 - 264
Copyright
Copyright © The Canadian Journal of Neurological 2012

References

1Zecca, L, Youdim, MBH, Riederer, P, Connor, JR, Crichton, RR.Iron, brain ageing and neurodegenerative disorders. Nat Rev Neurosci. 2004; 5(11): 863–73.Google Scholar
2Hayflick, SJ, Westaway, SK, Levinson, B, et al.Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome. N Engl J Med. 2003; 348(1): 33–40.Google Scholar
3Schneider, SA, Hardy, J, Bhatia, KP.Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations. Mov Disord. 2012; 27(1): 42–53.Google Scholar
4Gregory, A, Hayflick, SJ.Genetics of neurodegeneration with brain iron accumulation. Curr Neurol Neurosci Rep. 2011; 11(3): 254–61.CrossRefGoogle ScholarPubMed
5Kruer, MC, Boddaert, N, Schneider, SA, et al.Neuroimaging features of neurodegeneration with brain iron accumulation. AJNR Am J Neuroradiol. 2011; Sep 15 as 10.3174/ajnr.A2677 [Epub ahead of print].Google Scholar
6Kurian, MA, McNeill, A, Lin, JP, Maher, ER.Childhood disorders of neurodegeneration with brain iron accumulation (NBIA). Dev Med Child Neurol. 2011; 53(5): 394–404.Google Scholar
7Birbes, H, Bawab, SE, Obeid, LM, Hannun, YA.Mitochondria and ceramide: intertwined roles in regulation of apoptosis. Advan Enzyme Regul. 2002; 42: 113–29.Google Scholar
8Bras, J, Singleton, A, Cookson, MR, Hardy, J.Emerging pathways in genetic Parkinson’s disease: potential role of ceramide metabolism in Lewy body disease. FEBS J. 2008; 275(23): 5767–73.Google Scholar
9Zhou, B, Westaway, SK, Levinson, B, Johnson, MA, Gitschier, J, Hayflick, SJ.A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet. 2001; 28(4): 345–9.Google Scholar
10Kim, J, Cho, JW, Shin, H, Yoon, J, Ki, CS, Cho, AR.A novel PANK2 gene mutation with sudden-onset dystonia like psychogenic movement. Can J Neurol Sci. 2012; 39(3):395–7.Google Scholar