Hostname: page-component-8448b6f56d-jr42d Total loading time: 0 Render date: 2024-04-19T16:54:56.887Z Has data issue: false hasContentIssue false
  • English
  • Français

Ganglioglioneurocytoma of the Posterior Fossa

Published online by Cambridge University Press:  02 December 2014

Ahmed M. Alkhani ,
Juan M. Bilbao ,
Paul Medline  and
Fadegbola A. Ogundimu
Ahmed M. Alkhani
Affiliation:
Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
Juan M. Bilbao
Affiliation:
Division of Neuropathology, University of Toronto, Toronto, Ontario, Canada
Paul Medline
Affiliation:
Department of Pathology, Sudbury General Hospital, Sudbury, Ontario, Canada
Fadegbola A. Ogundimu
Affiliation:
Department of Neurosurgery, Sudbury General Hospital, Sudbury, Ontario, Canada
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Objective and Importance:

Ganglioglioneurocytoma is not yet a well defined clinical and histopathological entity; recent reports outline the histopathological features of this very rare trimorphous tumor, under different names with its basic components of gangliocytoma, neurocytoma and glioma. Four previous reports described this tumor in eleven patients. This is the first case report describing ganglioglioneurocytoma in the posterior fossa.

Clinical Presentation and Intervention:

A 31-year old male with midline posterior fossa ganglioglioneurocytoma is described, providing the neuroimages and histopathological studies.

Conclusion:

Ganglioglioneurocytoma is a rare mixed neuronal and glial tumor that can also occur in the posterior fossa.

Résumé

RÉSUMÉ<span class='bold'><span class='italic'>Objectif et importance:</span></span>

Le ganglioglioneurocytome est encore une entité clinique et histopathologique mal définie. Des rapports récents décrivent sous des noms dif- férents les caractéristiques histopathologiques de cette tumeur très rare, possédant trois composantes de base, le gan- gliocytome, le neurocytome et le gliome. Quatre rapports antérieurs décrivent cette tumeur chez onze patients. Nous présentons le premier cas d’un ganglioglioneurocytome de la fosse postérieure.

<span class='italic'><span class='bold'>Présentation clinique et intervention:</span></span>

Nous décrivons le cas d’un homme âgé de trente et un ans porteur d’un ganglioglioneurocytome médian de la fosse postérieure et nous en présentons la neuro-imagerie et l’anatomopathologie.

<span class='italic'><span class='bold'>Conclusion:</span></span>

Le ganglioglioneu- rocytome est une tumeur mixte neuronale et gliale rare qui peut également être localisée dans la fosse postérieure.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 26 , Issue 3 , November 1999 , pp. 207 - 210
Copyright
Copyright © The Canadian Journal of Neurological 1999

References

1. Miller, DC, Lang, FF, Epstein, FJ. Central nervous system gangliogliomas. Part 1: Pathology. J Neurosurg 1993; 79:859–866.CrossRefGoogle Scholar
2. Nishio, S, Takeshita, I, Kameko, Y, et al. Cerebral neurocytoma. Cancer 1992; 70: 529–537.3.0.CO;2-0>CrossRefGoogle ScholarPubMed
3. Eram, S, Rosenblum, M, Ho, K. Neurocytoma in the cerebellum. J Neurosurg 1997; 87:100–102.Google Scholar
4. Constantini, S, Houten, J, Miller, D, et al. Intramedullary spinal cordtumors in children under the age of 3 years. J Neurosurg 1996; 85:1036–1043.CrossRefGoogle ScholarPubMed
5. Min, DC, Cashman, R, Brumback, R: Glioneurocytoma. Tumor withglial and neuronal differentiation. J Child Neurol 1995; 10(3): 219–226.CrossRefGoogle ScholarPubMed
6. Nishio, S, Takeshita, I, Fukui, M: Primary cerebral ganglioneurocytoma in an adult. Cancer 1990; 66:358–362.3.0.CO;2-8>CrossRefGoogle ScholarPubMed
7. Miller, DC, Kim, R, Zagzag, D. Neurocytomas: non-classical sitesand mixed elements. J Neuropathol Exp Neurol 1992; 51:364(abstract).Google Scholar
8. Giangaspero, F, Cenacchi, G, Losi, L, et al. Extraventricular neo-plasms with neurocytoma features. Am J Surg Pathol 1997; 21(2): 206–212.CrossRefGoogle Scholar
9. Schweitzer, J, Davies, K. Differentiating central neurocytoma. J Neurosurg 1997; 86:534–546.CrossRefGoogle ScholarPubMed
10. Yamamoto, T, Komori, T, Shibata, N, et al. Multifocal Neurocytoma/Gangliocytoma with Extensive Leptomeningeal Dissemination in the Brain and Spinal Cord. Am J Surg Pathol 1996; 20(3): 363–370.CrossRefGoogle ScholarPubMed
11. Iantos, PL, VanderBerg, SR, Kleihues, P. In: Graham, DI and Iantos, PL, eds. Greenfield’s Neuropathology, Vol. 2. London: Arnold, 1997: 661.Google Scholar
12. Von Deimling, A, Janzer, R, Kleihues, P, et al. Patterns of differentiation in central neurocytoma. An immunohistochemical study of eleven biopsies. Acta Neuropathol 1990; 79:473–479.CrossRefGoogle ScholarPubMed