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Cognitive Therapy in the Treatment of Non-Responders to Antidepressant Medication: A Controlled Pilot Study

Published online by Cambridge University Press:  16 June 2009

Richard G. Moore  and
Ivy-Marie Blackburn
Richard G. Moore
Affiliation:
University of Cambridge
Ivy-Marie Blackburn
Affiliation:
Newcastle City Health NHS Trust
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Abstract

In outpatients with recurrent major depression who failed to respond to acute treatment with antidepressant medication, this study compared the effects of follow-up treatment with cognitive therapy with those of follow-up treatment with medication. In the small number of patients treated, there were some indications of response to cognitive therapy. A greater number of patients responded at least partially to cognitive therapy according to one of the two response criteria, and mean scores on two measures of depression changed to a greater extent with cognitive therapy than with continued medication. Results are consistent with previous studies, but replication is required due to the small numbers involved. The potential implications for provision of treatment are discussed.

Type
Clinical Section
Information
Behavioural and Cognitive Psychotherapy , Volume 25 , Issue 3 , July 1997 , pp. 251 - 259
Copyright
Copyright © British Association for Behavioural and Cognitive Psychotherapies 1997

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References

Beck, A. T., Rush, A. J., Shaw, B. F., & Emery, G. (1979). Cognitive therapy of depression. New York: Guilford Press.Google Scholar
Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.Google Scholar
Carney, M. W. P., Roth, M., & Garside, R. F. (1965). The diagnosis of depressive syndromes and the prediction of ECT response. British Journal of Psychiatry, 111, 659–674.CrossRefGoogle Scholar
Elkin, I., Shea, M. T., Watkins, J. T., Imber, S. D., Sotsky, S. M., Collins, J. F. et al. (1989). NIMH Treatment of Depression Collaborative Research Program: 1. General effectiveness of treatments. Archives of General Psychiatry, 46, 971–982.Google Scholar
Endicott, J. & Spitzer, R. L. (1978). A diagnostic interview: The schedule for affective disorders and schizophrenia. Archives of General Psychiatry, 25, 837–844.Google Scholar
Evans, M. D., Hollon, S. D., DeRubeis, R. J., Piasecki, J. M., Grove, W. M., Garvey, M. J., & Tuason, V. B. (1992). Differential relapse following cognitive therapy and pharmacotherapy for depression. Archives of General Psychiatry, 49, 802–808.Google Scholar
Fawcett, J. (1994). Antidepressants; Partial response in chronic depression. British Journal of Psychiatry, 165 (suppl. 26), 37–41.CrossRefGoogle Scholar
Fennell, M. J. V. & Teasdale, J. D. (1982). Cognitive therapy with chronic, drug-refractory depressed outpatients: A note of caution. Cognitive Therapy and Research, 6, 455–460.CrossRefGoogle Scholar
Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry, 23, 56–62.Google Scholar
Harpin, R. E., Liberman, R. P., Marks, I., Stern, R., & Bohannon, W. E. (1982). Cognitive-behaviour therapy for chronically depressed patients: A controlled pilot study. Journal of Nervous and Mental Disease, 170, 295–301.CrossRefGoogle ScholarPubMed
Hollon, S. D., Shelton, R. C. & Loosen, P. T. (1991). Cognitive therapy and pharmacotherapy for depression. Journal of Consulting and Clinical Psychology, 59, 88–99.Google Scholar
Mercier, M. A., Stewart, J. W., & Quitkin, F. M. (1992). A pilot sequential study of cognitive therapy and pharmacotherapy of atypical depression. Journal of Clinical Psychiatry, 53, 166–170.Google Scholar
Morris, J. B. & Beck, A. T. (1974). The efficacy of antidepressant drugs. Archives of General Psychiatry, 30, 667–674.CrossRefGoogle ScholarPubMed
Simons, A. D., Lustman, P. J., Wetzel, R. D., & Murphy, G. E. (1985). Predicting response to cognitive therapy of depression: The role of learned resourcefulness. Cognitive Therapy and Research, 9, 79–89.CrossRefGoogle Scholar
Spitzer, R. L., Endicott, J., & Robins, E. (1978). Research Diagnostic Criteria: Rationale and reliability. Archives of General Psychiatry, 35, 773–782.Google Scholar
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