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IGF-1 concentration patterns and their relationship with follicle development after weaning in young sows fed different pre-mating diets

Published online by Cambridge University Press:  29 January 2020

T. Han Open the ORCID record for T. Han [Opens in a new window] ,
S. Björkman ,
N. M. Soede ,
C. Oliviero  and
O. A. T Peltoniemi
T. Han*
Affiliation:
Production Animal Hospital, Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
S. Björkman
Affiliation:
Production Animal Hospital, Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
N. M. Soede
Affiliation:
Adaptation Physiology Group, Department of Animal Sciences, Wageningen University & Research, Wageningen, The Netherlands
C. Oliviero
Affiliation:
Production Animal Hospital, Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
O. A. T Peltoniemi
Affiliation:
Production Animal Hospital, Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
*
†E-mail: taehee.han@helsinki.fi
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Abstract

Piglet birth weight and within-litter birth weight variation are important for piglet survival and growth. Pre-mating diets may improve IGF-1 and follicle development during the weaning-to-oestrus interval (WEI) and subsequent piglet birth weight. The objective of this study was to modulate IGF-1 concentration during late lactation and the WEI of young sows by using specific pre-mating diets supplemented with microfibrillated cellulose (MF), l-carnitine (LC) or l-arginine (AR). A further objective was to investigate the relationship between IGF-1 and subsequent follicle development and oestrus and ovulation characteristics. In total, 56 first-parity and 20 second-parity sows in three consecutive batches were used for this experiment. Sows received daily either wheat (CON) or wheat plus MF, LC or AR at one of two supplementation levels (low and high) during last week of lactation and WEI. From weaning onwards, follicle and corpus luteum (CL) diameters were repeatedly measured with ultrasound. Blood samples were collected during the WEI for IGF-1 and on day 21 of pregnancy for progesterone analyses, respectively. Insulin-like growth factor-1 concentration, follicle diameter, oestrus and ovulation characteristics and CL diameter were not affected by pre-mating diets. Low IGF-1 class (≤156 ng/ml, N = 22) sows had smaller follicles at weaning (3.5 v. 3.8 mm, P < 0.05) and a longer weaning-to-ovulation interval (147.2 v. 129.8 h, P < 0.05) than high IGF-1 class sows. In first-parity sows, high loin muscle depth (LM) loss sows (≥8%, N = 28) had lower IGF-1 concentrations at weaning (167 v. 214 ng/ml, P < 0.05) compared to low LM loss sows (<8%, N = 28). However, after weaning, IGF-1 concentrations increased and did not differ between high LM loss and low LM loss sows. In conclusion, the different supplemented compounds in pre-mating diets did not improve IGF-1 concentrations around weaning in young sows. Furthermore, high body condition loss caused lower IGF-1 concentrations at weaning, but these levels rapidly recovered after weaning and were related to follicle development and the interval from weaning to ovulation.

Keywords

sow reproductionIGFmetabolic statefollicular developmentsow body condition
Type
Research Article
Information
animal , Volume 14 , Issue 7 , July 2020 , pp. 1493 - 1501
Copyright
© The Animal Consortium 2020

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References

Arts, CJ, Govers, CA, van den Berg, H, Wolters, MG, van Leeuwen, P and Thijssen, JH 1991. In vitro binding of estrogens by dietary fiber and the in vivo apparent digestibility tested in pigs. The Journal of Steroid Biochemistry and Molecular Biology 38, 621–628.CrossRefGoogle ScholarPubMed
Baxter, EM, Jarvis, S, D’eath, RB, Ross, DW, Robson, SK, Farish, M and Edwards, SA 2008. Investigating the behavioural and physiological indicators of neonatal survival in pigs. Theriogenology 69, 773–783.CrossRefGoogle ScholarPubMed
Birkenfeld, C, Ramanau, A, Kluge, H, Spilke, J and Eder, K 2005. Effect of dietary l‐carnitine supplementation on growth performance of piglets from control sows or sows treated with l‐carnitine during pregnancy and lactation. Journal of Animal Physiology and Animal Nutrition 89, 277–283.CrossRefGoogle ScholarPubMed
Bracken, CJ, Lamberson, WR, Safranski, TJ and Lucy, MC 2003. Factors affecting follicular populations on Day 3 postweaning and interval to ovulation in a commercial sow herd. Theriogenology 60, 11–20.CrossRefGoogle Scholar
Britt, JH, Armstrong, JD, Cox, NM and Esbenshade, KL 1985. Control of follicular development during and after lactation in sows. Journal of Reproduction and Fertility 33 (suppl.), 37–54.Google ScholarPubMed
Campos, PHRF, Silva, BAN, Donzele, JL, Oliveira, RFM and Knol, EF 2012. Effects of sow nutrition during gestation on within-litter birth weight variation: a review. Animal 6, 797–806.CrossRefGoogle ScholarPubMed
Costermans, NGJ, Teerds, KJ, Middelkoop, A, Roelen, BAJ, Schoevers, EJ, van Tol, HTA, Laurenssen, B, Koopmanschap, RE, Zhao, Y, Blokland, M, van Tricht, F, Zak, L, Keijer, J, Kemp, B and Soede, NM 2019. Consequences of negative energy balance on follicular development and oocyte quality in primiparous sows. Biology of Reproduction, doi:10.1093/biolre/ioz175.Google Scholar
Doberenz, J, Birkenfeld, C, Kluge, H and Eder, K 2006. Effects of L‐carnitine supplementation in pregnant sows on plasma concentrations of insulin‐like growth factors, various hormones and metabolites and chorion characteristics. Journal of Animal Physiology and Animal Nutrition 90, 487–499.CrossRefGoogle ScholarPubMed
Ferguson, EM, Ashworth, CJ, Hunter, MG, Penny, P, Slevin, J and Edwards, SA 2004. The effect of feeding a high fibre diet from mid lactation until breeding on subsequent litter size of sows. BSAP Occasional Publication 31, 175–179.CrossRefGoogle Scholar
Ferguson, EM, Slevin, J, Hunter, MG, Edwards, SA and Ashworth, CJ 2007. Beneficial effects of a high fibre diet on oocyte maturity and embryo survival in gilts. Reproduction 133, 433–439.CrossRefGoogle ScholarPubMed
Guo, P, Jiang, ZY, Gao, KG, Wang, L, Yang, XF, Hu, YJ and Ma, XY 2017. Low-level arginine supplementation (0.1%) of wheat-based diets in pregnancy increases the total and live-born litter sizes in gilts. Animal Production Science 57, 1091–1096.CrossRefGoogle Scholar
Hoving, LL, Soede, NM, Feitsma, H and Kemp, B 2012. Lactation weight loss in primiparous sows: consequences for embryo survival and progesterone and relations with metabolic profiles. Reproduction in Domestic Animals 47, 1009–1016.CrossRefGoogle ScholarPubMed
Langendijk, P, Van den Brand, H, Soede, NM and Kemp, B 2000. Effect of boar contact on follicular development and on estrus expression after weaning in primiparous sows. Theriogenology 54, 1295–1303.CrossRefGoogle ScholarPubMed
Louveau, I and Bonneau, M 1996. Effect of a growth hormone infusion on plasma insulin-like growth factor-I in Meishan and large white pigs. Reproduction Nutrition Development 36, 301–310.CrossRefGoogle ScholarPubMed
Lucy, MC 2008. Functional differences in the growth hormone and insulin‐like growth factor axis in cattle and pigs: implications for post‐partum nutrition and reproduction. Reproduction in Domestic Animals 43, 31–39.CrossRefGoogle ScholarPubMed
Mejia-Guadarrama, CA, Pasquier, A, Dourmad, JY, Prunier, A and Quesnel, H 2002. Protein (lysine) restriction in primiparous lactating sows: effects on metabolic state, somatotropic axis, and reproductive performance after weaning. Journal of Animal Science 80, 3286–3300.CrossRefGoogle ScholarPubMed
Musser, RE, Goodband, RD, Tokach, MD, Owen, KQ, Nelssen, JL, Blum, SA, Dritz, SS and Civis, CA 1999. Effects of L-carnitine fed during gestation and lactation on sow and litter performance. Journal of Animal Science 77, 3289–3295.CrossRefGoogle ScholarPubMed
Pope, WF, Xie, S, Broermann, DM and Nephew, KP 1990. Causes and consequences of early embryonic diversity in pigs. Journal of Reproduction and Fertility 40 (suppl.), 251–260.Google ScholarPubMed
Quesnel, H, Etienne, M and Père, MC 2007. Influence of litter size on metabolic status and reproductive axis in primiparous sows. Journal of Animal Science 85, 118–128.CrossRefGoogle ScholarPubMed
Quesnel, H, Pasquier, A, Mounier, AM, Louveau, I and Prunier, A 1998. Influence of feed restriction in primiparous lactating sows on body condition and metabolic parameters. Reproduction Nutrition Development 38, 261–274.CrossRefGoogle ScholarPubMed
Serpa, A, Velásquez-Cock, J, Gañán, P, Castro, C, Vélez, L and Zuluaga, R 2016. Vegetable nanocellulose in food science: a review. Food Hydrocolloids 57, 178–186.Google Scholar
Van den Brand, H, Prunier, A, Soede, NM and Kemp, B 2001. In primiparous sows, plasma insulin-like growth factor-I can be affected by lactational feed intake and dietary energy source and is associated with luteinizing hormone. Reproduction Nutrition Development 41, 27–39.CrossRefGoogle ScholarPubMed
Van den Brand, H, Soede, NM and Kemp, B 2006. Supplementation of dextrose to the diet during the weaning to estrus interval affects subsequent variation in within-litter piglet birth weight. Animal Reproduction Science 91, 353–358.CrossRefGoogle ScholarPubMed
Van den Brand, H, Van Enckevort, LCM, Van der Hoeven, EM and Kemp, B 2009. Effects of dextrose plus lactose in the sows diet on subsequent reproductive performance and within litter birth weight variation. Reproduction in Domestic Animals 44, 884–888.CrossRefGoogle ScholarPubMed
Van der Lende, T, Hazeleger, W and De Jager, D 1990. Weight distribution within litters at the early foetal stage and at birth in relation to embryonic mortality in the pig. Livestock Production Science 26, 53–65.CrossRefGoogle Scholar
Wang, J, Feng, C, Liu, T, Shi, M, Wu, G and Bazer, FW 2017. Physiological alterations associated with intrauterine growth restriction in fetal pigs: causes and insights for nutritional optimization. Molecular Reproduction and Development 84, 897–904.CrossRefGoogle ScholarPubMed
Wientjes, JGM, Soede, NM, Knol, EF, Van den Brand, H and Kemp, B 2013b. Piglet birth weight and litter uniformity: effects of weaning-to-pregnancy interval and body condition changes in sows of different parities and crossbred lines. Journal of Animal Science 91, 2099–2107.CrossRefGoogle ScholarPubMed
Wientjes, JGM, Soede, NM, Laurenssen, BFA, Koopmanschap, RE, Van Den Brand, H and Kemp, B 2013a. Insulin-stimulating diets during the weaning-to-estrus interval do not improve fetal and placental development and uniformity in high-prolific multiparous sows. Animal 7, 1307–1316.CrossRefGoogle Scholar
Wientjes, JGM, Soede, NM, Van den Brand, H and Kemp, B 2012b. Nutritionally induced relationships between insulin levels during the weaning‐to‐ovulation interval and reproductive characteristics in multiparous sows: I. Luteinizing hormone, follicle development, oestrus and ovulation. Reproduction in Domestic Animals 47, 53–61.CrossRefGoogle ScholarPubMed
Wientjes, JGM, Soede, NM, Van den Brand, H and Kemp, B 2012c. Nutritionally induced relationships between insulin levels during the weaning-to-ovulation interval and reproductive characteristics in multiparous sows: II. Luteal development, progesterone and conceptus development and uniformity. Reproduction in Domestic Animals 47, 62–68.CrossRefGoogle ScholarPubMed
Wientjes, JGM, Soede, NM, Van der Peet-Schwering, CMC, Van den Brand, H and Kemp, B 2012a. Piglet uniformity and mortality in large organic litters: effects of parity and pre-mating diet composition. Livestock Science 144, 218–229.CrossRefGoogle Scholar
Zak, LJ, Xu, X, Hardin, RT and Foxcroft, GR 1997. Impact of different patterns of feed intake during lactation in the primiparous sow on follicular development and oocyte maturation. Reproduction 110, 99–106.CrossRefGoogle ScholarPubMed
Zhu, C, Guo, CY, Gao, KG, Wang, L, Chen, Z and Jiang, ZY 2017. Dietary arginine supplementation in multiparous sows during lactation improves the weight gain of suckling piglets. Journal of Integrative Agriculture 16, 648–655.CrossRefGoogle Scholar
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