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Single nucleotide polymorphisms in the growth hormone and IGF type-1 (IGF1) genes associated with carcass traits in Santa Ines sheep

Published online by Cambridge University Press:  06 July 2018

A. N. Meira
Affiliation:
Animal Science Department, Federal University of Bahia, Av. Adhemar de Barros, 500Ondina – Salvador, BA 40170-110, Brazil
H. Montenegro
Affiliation:
São Paulo University, Av. Pádua Dias, 11Agronomia – Piracicaba, SP 13635-900, Brazil
L. L. Coutinho
Affiliation:
São Paulo University, Av. Pádua Dias, 11Agronomia – Piracicaba, SP 13635-900, Brazil
G. B. Mourão
Affiliation:
São Paulo University, Av. Pádua Dias, 11Agronomia – Piracicaba, SP 13635-900, Brazil
H. C. Azevedo
Affiliation:
EMBRAPA Costal Tablelands, Av. Beira Mar, n° 3,250Jardins – Aracaju, SE 49025-040, Brazil
E. N. Muniz
Affiliation:
EMBRAPA Costal Tablelands, Av. Beira Mar, n° 3,250Jardins – Aracaju, SE 49025-040, Brazil
A. L. Machado
Affiliation:
Animal Science Department, Federal University of Bahia, Av. Adhemar de Barros, 500Ondina – Salvador, BA 40170-110, Brazil
L. P. Sousa-Jr
Affiliation:
Animal Science Department, Federal University of Bahia, Av. Adhemar de Barros, 500Ondina – Salvador, BA 40170-110, Brazil
V. B. Pedrosa
Affiliation:
State University of Ponta Grossa, Av. General Carlos Cavalcanti, 4748Uvaranas – Ponta Grossa, PR 84030-900, Brazil
L. F. B. Pinto
Affiliation:
Animal Science Department, Federal University of Bahia, Av. Adhemar de Barros, 500Ondina – Salvador, BA 40170-110, Brazil
Corresponding
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Abstract

Polymorphisms in the growth hormone (GH) and IGF type-1 (IGF1) genes have been associated with the economic traits in farm animals, including BW of some sheep breeds. However, it remains unknown if these polymorphisms also affect carcass traits in sheep. Thus, we aimed to identify polymorphisms in the GH and IGF1 genes in Santa Ines sheep in order to describe their allelic and genotypic frequencies as well as to test the hypotheses that they are associated with the carcass traits. Fragments of 4550 bp (IGF1) and 1194 bp (GH) were sequenced in up to 191 lambs. In all, 18 polymorphisms were identified in the IGF1 and 21 in the GH gene. The IGF1 polymorphisms rs430457475, rs412470350, rs409110739 and rs400113576 showed an additive effect on the internal carcass length (−0.9265±0.4223), rump girth (−2.9285±1.1473), rib yield (−1.0003±0.4588) and neck weight (−0.0567±0.0278), respectively. In addition, the polymorphisms rs58957314 in the GH affected the rib weight (−0.4380±0.1272) and rib yield (−2.2680±0.6970), loin weight (−0.1893±0.0516) and loin yield (−0.9423±0.3259), palette weight (−0.2265±0.0779) and palette yield (−0.9424±0.4184), leg weight (−0.3960±0.1375), neck weight (−0.0851±0.0394) and carcass finishing score (−0.1700±0.0839). These results allow us to conclude that there are polymorphisms in the IGF1 and GH genes associated with carcass traits in Santa Ines sheep, which can provide important information for marker-assisted selection.

Type
Research Article
Copyright
© The Animal Consortium 2018 

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Single nucleotide polymorphisms in the growth hormone and IGF type-1 (IGF1) genes associated with carcass traits in Santa Ines sheep
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