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Influence of trenbolone acetate, zeranol and oestradiol-17β implantation on growth performance and reproductive function in beef heifers

Published online by Cambridge University Press:  02 September 2010

A. Zarkawi ,
H. Galbraith  and
J. S. M. Hutchinson
A. Zarkawi
Affiliation:
Department of Agriculture, University of Aberdeen, Aberdeen AB9 1UD
H. Galbraith
Affiliation:
Department of Agriculture, University of Aberdeen, Aberdeen AB9 1UD
J. S. M. Hutchinson
Affiliation:
Department of Agriculture, University of Aberdeen, Aberdeen AB9 1UD Rowett Research Institute, Bucksburn, Aberdeen AB2 9SB
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Abstract

Twenty-four Hereford ♂ × Friesian ♀ heifers were divided into four equal treatment groups and given subcutaneous ear implants as appropriate 14 days after prostaglandin treatment for the induction of synchronized cycles. Subsequently, they were observed for 75 days. One group was an untreated control, one was given 300 mg trenbolone acetate, one 36 mg zeranol and one 45 mg oestradiol-176. Growth and ovarian cyclicity, assessed by periodic progesterone measurement, were monitored. Trenbolone acetate-treated heifers grew faster (P < 0·05) than other groups which did not differ significantly. Trenbolone acetate shortened the oestrous cycle in which treatment was started in two of five heifers and lengthened it in two others. Subsequent cycles were either suppressed or of short duration. Zeranol and oestradiol-176 treatment had little effect on ovarian cyclicity apart from a small increase in the number of short cycles. It is concluded that, at the doses used, trenbolone acetate suppresses mechanisms leading to ovulation or pre-ovulatory follicular development.

Keywords

anabolic steroidsgrowthheifersreproductive performance
Type
Research Article
Information
Animal Production , Volume 52 , Issue 2 , April 1991 , pp. 249 - 253
Copyright
Copyright © British Society of Animal Science 1991

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References

REFERENCES

Elsasser, T. H., Bolt, D. J., Bradley, B. D. and Roper, M. 1983. Luteinizing hormone, follicle stimulating hormone and prolactin secretion in ewes and wethers after zeranol or estradiol injection. Journal of Animal Science 57: 443–448.CrossRefGoogle ScholarPubMed
Fuller, T. S., Dunn, T. G., Kaltenbach, C. C. and Waggoner, J. W. 1980. Effect of zeranol on estrus and pregnancy in beef heifers. Journal of Animal Science 51: Suppl. 1, pp. 279–280.Google Scholar
Galbraith, H. 1980. The effect of trenbolone acetate on growth, blood hormones and metabolites, and nitrogen balance of beef heifers. Animal Production 30: 389–394.Google Scholar
Hanning, R., Orczyk, G. P., Caldwell, B. V. and Behrman, H. R. 1979. Plasma estradiol, estrone, estriol and urinary estriol glucuronide. In Methods of Hormone Radioimmunoassay. 2nd ed. (ed. Jaffe, B. M. and Behrman, H. R.), pp. 675–700. Academic Press, New York.Google Scholar
Henricks, R. M., Edwards, R. L., Champe, K. A., Gettys, T., Skelley, G. C. and Gimenez, T. 1982. Trenbolone, estradiol-17B and estrone levels in plasma and tissues and live weight gains of heifers implanted with trenbolone acetate. Journal of Animal Science 55: 1048–1056.CrossRefGoogle Scholar
Lawes Agricultural Trust. 1977. Genstat 4.01. Statistics Department, Rothamsted Experimental Station, Harpenden.Google Scholar
MacVinish, L. J., Galbraith, H. and Chesworth, J. M. 1983. Steroid concentrations in sheep implanted with trenbolone acetate. Proceedings of the Nutrition Society 42: 57A.Google Scholar
Neumann, F. 1976. Pharmacological and endocrinological studies on anabolic agents. In Anabolic Agents in Animal Production V (ed. Coulston, F. and Korte, F.), pp. 253–264. George Thieme, Stuttgart.Google Scholar
Orczyk, G. A., Hichens, M., Arth, G. and Behrman, H. R. 1979. Progesterone and 20 a dihydroprogesterone. In Methods of Hormone Radioimmunoassay. 2nd ed. (ed. Jaffe, B. M. and Behrman, H. R.), pp. 703–713. Academic Press, New York.Google Scholar
Peters, A. R. 1985. Hormonal control of the bovine oestrous cycle. I. The natural cycle. British Veterinary Journal 141: 564–575.CrossRefGoogle ScholarPubMed
Reynolds, I. P., Harrison, L. P., Mallinson, C. B., Harwood, D. J. and Heitzman, R. J. 1981. The effect of trenbolone acetate on the bovine oestrous cycle. Animal Reproduction Science 4: 107–116.CrossRefGoogle Scholar
Roche, H. F. 1980. The use of growth promoters in beef cattle. In The Use, Residues and Toxicology of Growth Promoters, pp. 1–12. An Foras Taliintais.Google Scholar
Roche, J. F. and Quirke, J. F. 1986. The effects of steroid hormones and xenobiotics on growth of farm animals In Control and Manipulation of Animal Growth (ed. Buttery, P. J., Haynes, N. B. and Lindsay, D. B.), pp. 39–52. Butterworths, London.CrossRefGoogle Scholar
Sharp, G. D. and Dyer, I. A. 1971. Effect of zearalanol on the performance and carcass composition of growing-finishing ruminants. Journal of Animal Science 33: 865–871.CrossRefGoogle Scholar
Staigmiller, R. B., Bellows, R. A. and Short, R. E. 1983. Growth and reproductive traits in beef heifers implanted with zeranol. Journal of Animal Science 57: 527–534.CrossRefGoogle ScholarPubMed
Zarkawi, M., Galbraith, H. and Hutchinson, J. S. M. 1991. The action of trenbolone acetate, a synthetic anabolic steroid, on ovarian function in the guineapig. Laboratory Animals. In press.Google Scholar