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Effect of supplemental levels of chromium picolinate on the growth performance, serum traits, carcass characteristics and lipid metabolism of growing-finishing pigs

Published online by Cambridge University Press:  18 August 2016

T.-F. Lien ,
C.-P. Wu ,
B.-J. Wang ,
M.-S. Shiao ,
T.-Y. Shiao ,
B.-H. Lin ,
J.-J. Lu  and
C.-Y. Hu
T.-F. Lien
Affiliation:
Department of Animal Science, National Chiayi University, Chiayi, Taiwan Republic of China
C.-P. Wu
Affiliation:
Department of Animal Science, National Chiayi University, Chiayi, Taiwan Republic of China
B.-J. Wang
Affiliation:
Department of Food Science, National Chiayi University, Chiayi , Taiwan, Republic of China
M.-S. Shiao
Affiliation:
Department of Medical Research, Veterans General Hospital, Taipei, Taiwan, Republic of China
T.-Y. Shiao
Affiliation:
Department of Food Science, National Chiayi University, Chiayi , Taiwan, Republic of China
B.-H. Lin
Affiliation:
Department of Animal Science, National Chiayi University, Chiayi, Taiwan Republic of China
J.-J. Lu
Affiliation:
Department of Animal Science, National Chiayi University, Chiayi, Taiwan Republic of China
C.-Y. Hu
Affiliation:
Department of Animal Science, Oregon State University, Corvallis, Oregon, USA
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Abstract

This study investigated the effect of chromium picolinate supplementation on growth performance, carcass characteristics and lipid metabolism of growing-finishing pigs. Sixty Landrace ✕ Yorkshire ✕ Duroc (LYD) pigs with a mean initial body weight of 46·65 (s.e. 6·72) kg were randomly allocated into three groups with two replicates. They were supplemented with 0 , 200, or 400 μg/kg (ppb) chromium in the organic form of chromium picolinate for 90 days. Supplementation with chromium picolinate in the pigs’ ration improved their growth performance, enhanced average daily gain (P < 0·05), and increased their food consumption, especially in the 200 ppb group ( P > 0·05). Chromium picolinate supplementation also improved carcass characteristics, as the average back fat thickness was reduced and the loin-eye area was enhanced ( P < 0·05). The serum chromium concentration in the chromium picolinate supplemented groups was approximately twice that of the controls ( P < 0·05). Supplementation with chromium also markedly reduced serum total cholesterol, triacylglycerol (TG) and urea concentrations in the pig serum ( P < 0·05). Serum insulin was significantly decreased in the 400 ppb group, while serum glucose was decreased in the 200 ppb group ( P < 0·05). Very low density lipoprotein (VLDL) was reduced and low density lipoprotein (LDL) was increased in the chromium supplementation group. Meanwhile, the high density lipoprotein-cholesterol and VLDL-cholesterol were markedly increased, while LDL-cholesterol was significantly diminished ( P < 0·05) in the 200 ppb group. The adipocyte diameter and volume in the chromium-supplemented groups tended to be larger than in the control ( P = 0·07). In vitro studies indicated that incorporation of [u, 14C]glucose into total lipids (P < 0·05) was increased by chromium supplementation. However, there were no lipolysis differences among the groups (P > 0·05). The carcasses of the pigs that received the chromium supplemented ration contained less oleic acid (C18 : 1) and total unsaturated fatty acids (P < 0·05). On the other hand, the total saturated fatty acid content was higher than that of the controls (P < 0·05). Results in this study demonstrate that chromium picolinate supplementation in pigs has several beneficial effects.

Keywords

carcass compositionchromium picolinatelipid metabolismpigs.
Type
Growth, development and meat science
Information
Animal Science , Volume 72 , Issue 2 , April 2001 , pp. 289 - 296
Copyright
Copyright © British Society of Animal Science 2001

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References

Amoikon, E. K., Fernandez, J. M., Southern, L. L., Thompson, D. L. Jr., Ward, T. L. and Olcott, B. M. 1995. Effect of chromium tripicolinate on growth glucose tolerance, insulin sensitivity, plasma metabolites, and growth hormone in pigs. Journal of Animal Science 73: 1123–1130.Google Scholar
Anderson, R. A. 1986. Chromium metabolism and its role in disease processes in man. Clinical Physiology and Biochemistry 4: 31–41.Google ScholarPubMed
Anderson, R. A., Bryden, N. K. and Polansky, M. M. 1985. Serum chromium of human subjects: effects of chromium supplementation and glucose metabolism. American Journal of Clinical Nutrition 41: 571–577.Google Scholar
Anderson, R. A., Polansky, M. M., Bryden, N. A., Bhathena, S. J. and Canary, J. J. 1987. Effects of supplemental chromium on patients with symptoms of reactive hypoglycemia. Metabolism 38: 351–355.Google Scholar
Anderson, R. A., Polansky, M. P., Bryden, N. A. and Canary, J. J. 1991. Supplemental chromium effects on glucose, insulin, glucagon and urinary chromium losses in subjects consuming controlled low-chromium diets. American Journal of Clinical Nutrition 54: 909–916.Google Scholar
Boleman, S. L., Boleman, S. J., Bidner, T. D., Southern, L. L., Ward, T. L., Pontif, J. E. and Pike, M. M. 1995. Effect of chromium picolinate on growth, body composition, and tissue accretion in pigs. Journal of Animal Science 73: 2033–2042.Google Scholar
Brindley, D. N. and Salter, A. M. 1991. Hormonal regulation of the hepatic low density lipoprotein: relationship with the secretion of very low density lipoprotein. Journal of Lipid Research 30: 349–360.Google Scholar
Chang, X. and Mowat, D. N. 1992. Supplemental chromium for stressed and growing feeder calves. Journal of Animal Science 70: 559–565.Google Scholar
Chromy, V., Gergel, J. and Voznicek, J. 1977. Assay of serum free fatty acids by extraction-photometric procedures. Clinica Chemica Acta 80: 327–332.Google Scholar
Cupo, M. A. and Donaldson, W. E. 1987. Chromium and vanadium effect on glucose metabolism and lipids synthesis in the chick. Poultry Science 66: 120–126.Google Scholar
Dowling, H. J., Offenbacher, E.G. and Pi-Sunyer, F. X. 1989. Absorption of inorganic, trivalent chromium from the vascularly perfused rat small intestine. Journal of Nutrition 119: 1138–1145.Google Scholar
Etherton, T. D., Thompson, E. H. and Allen, C. E. 1977. Improved techniques for studies of adipocyte cellularity and metabolism. Journal of Lipid Research 18: 552–557.Google Scholar
Evans, G. W. 1982. The role of picolinic acid in metal metabolism. Life Chemistry Reports 1: 57–67.Google Scholar
Evans, G. W. 1989. The effect of chromium picolinate on insulin controlled parameters in humans. International Journal of Biophysical and Medical Research 11: 163–180.Google Scholar
Evans, G. W. and Bowman, T. D. 1992. Chromium picolinate increases membrane fluidity and rate of insulin internalization. Journal of Inorganic Biochemistry 46: 243–250.Google Scholar
Evock-Clover, C.M, Polansky, M. M., Anderson, R. A. and Steel, N. C. 1993. Dietary chromium supplementation with or without somatotropin treatment alters serum hormones and metabolites in growing pigs without affecting growth performance. Journal of Nutrition 123: 1504–1512.Google Scholar
Folch, T., Lees, M. and Stanley, G. H. S. 1957. A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 226: 497–509.Google Scholar
Gibson, R. S. 1989. Assessment of trace element status in humans. Progress in Food and Nutrition Science 13: 67–111.Google Scholar
Howard, B. V., Schneiderman, N., Falkner, B., Haffner, S. M. and Laws, A. 1993. Insulin, health behaviors, and lipid metabolism. Metabolism 42: (suppl. 1)25–35.Google Scholar
Lefavi, R. G., Wilson, G. D., Keith, R. E., Anderson, R. A., Blessing, D. L., Hames, C. G. and McMillan, J. L. 1993. Lipid-lowering effect of a dietary chromium (III) nicotinic acid complex in male athletes. Nutrition Research 13: 239–249.Google Scholar
Li, Y. C. 1990. Effects of chromium and vanadate supplementation on obese and lean mice. Journal of the Chinese Nutrition Society 15: 41–52.Google Scholar
Li, Y. C. and Fan, T. S. 1991. Chromium, vanadium and molybdenum effects on C 57BL/6J-OB mice and lean littermates. Journal of the National Pingtung Institute of Agriculture 32: 15–31.Google Scholar
Li, Y. C. and Fan, T. S. 1992. The influence of chromium and vanadate on diabetic mice and their littermates. Journal of the National Pingtung Institute of Agriculture 32: 1–11.Google Scholar
Li, Y. C. and Stoecker, B. J. 1986. Chromium and yogurt effects on hepatic lipid and plasma glucose and insulin of obese and lean mice. Biological Trace Element Research 9: 233–242.Google Scholar
Lien, T. F., Chen, S. Y., Wu, C. P., Chen, C. L. and Hu, C. Y. 1996a. Effects of chromium picolinate and chromium chloride on growth performance and serum traits of growing-finishing swine. Proceeding of Western Section, American Society of Animal Science 47: 150–153.Google Scholar
Lien, T.-F., Wu, C.-P., Lin, B.-H., Wang, B.-J., Lu, J.-J. and Shiao, T.-Y. 1998. Effect of different protein and limiting amino acid levels coupled with a supplement of chromium picolinate on lipid metabolism and carcass characteristics of pigs. Animal Science 67: 601–607.Google Scholar
Lien, T. F., Wu, C. P., Lu, J. J. and Chou, R. G. R. 1996b. Effects of supplemental chromium picolinate on growth performances, serum traits and carcass characteristics of pigs. Journal of the Chinese Society of Animal Science 25: 253–260.Google Scholar
Lindemann, M. D., Wood, C. M., Harper, A. F., Kornegay, E. T. and Anderson, R. A. 1995. Dietary chromium picolinate additions improve gain: feed and carcass characteristics in growing finishing pigs and increase litter size in reproducing sows. Journal of Animal Science 73: 457–465.Google Scholar
McCarty, M.F. 1991. The case for supplemental chromium and a survey of clinical studies with chromium picolinate. Journal of Applied Nutrition 43: 58–66.Google Scholar
Mersmann, H. J. and Hu, C. Y. 1987. Factors affecting measurements of glucose metabolism and lipolytic rates in porcine adipose tissue slices in vitro. Journal of Animal Science 64: 148–164.Google Scholar
Mertz, W. 1975. Effects and metabolism of glucose tolerance factor. Nutrition Reviews 33: 129–135.Google Scholar
Mertz, W. 1993. Chromium in human nutrition: a review. Journal of Nutrition 123: 626–633.Google Scholar
Mertz, W., Toepfer, E. W., Roginski, E. E. and Polansky, M. M. 1974. Present knowledge of the role of chromium. Federation Proceedings 33: 2275–2280.Google Scholar
Mirsky, N. 1993. Glucose tolerance factor reduces blood glucose and fatty acids levels in diabetic rats. Journal of Inorganic Biochemistry 49: 123–128.Google Scholar
Mooney, K. W. and Cromwell, G. L. 1995. Effect of dietary chromium picolinate supplementation on growth, carcass characteristics, and accretion rates of carcass tissues in growing-finishing swine. Journal of Animal Science 73: 3351–3357.Google Scholar
Mooney, K. W. and Cromwell, G. L. 1997. Efficacy of chromium picolinate and chromium chloride as potential carcass modifiers in swine. Journal of Animal Science 75: 2661–2671.Google Scholar
Moonsie-Shageer, S. and Mowat, D. N. 1993. Effect of level of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves. Journal of Animal Science 71: 232–238.Google Scholar
Morris, B. W., Blumsohn, A., Neil, S. M. and Gray, T. A. 1992. The trace element chromium-a role in glucose homeostasis. American Journal of Clinical Nutrition 55: 989–991.CrossRefGoogle ScholarPubMed
Morris, B. W., Gray, T. A. and Macneil, S. 1993. Glucose-dependent uptake of chromium in human and rat insulinsensitive tissues. Clinical Science 84: 477–482.Google Scholar
Mossop, R. T. 1983. Effects of chromium III on fasting blood glucose, cholesterol and HDL cholesterol levels in diabetics. The Central African Journal of Medicine 29: 80–82.Google Scholar
National Research Council. 1989. Recommended dietary allowances. National Academy Press, Washington, DC.Google Scholar
Newshome, E. A. 1974. Regulation in metabolism. Arrowsmith Co. Press, New York.Google Scholar
Novakofski, J. and Hu, C. Y. 1987. Culture of isolated adipose tissue cells. Journal of Animal Science 65: (suppl. 2) 12–24.Google Scholar
Offenbacher, E.G., Rinko, C. J. and Pi-Sunyer, F.X. 1985. The effects of inorganic chromium and brewer’s yeast on glucose tolerance, plasma lipids, and plasma chromium in elderly subjects. American Journal of Clinical Nutrition 42: 454–461.Google Scholar
Ohba, H., Suzuki, Y. and Ohba, H. 1986. Enhancement of ribonucleic acid synthesis by chromium(III)-bound chromatin. Journal of Inorganic Biochemistry 27: 179–188.Google Scholar
Okada, S., Tsukada, H. and Ohba, H. 1984. Enhancement of nucleo RNA synthesis by chromium(III) in regenerating rat liver. Journal of Inorganic Biochemistry 21: 113–119.Google Scholar
Page, T. G. 1991. Chromium, tryptophan and picolinate in diets for pigs and poultry. A dissertation, Louisiana State University.Google Scholar
Press, R. I., Geller, J. and Evans, G. W. 1990. The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects. The Western Journal of Medicine 152: 41–45.Google Scholar
Ranhotra, G. S. and Gelroth, J. A. 1986. Effects of high-chromium Baker’s yeast on glucose tolerance and blood lipids in rats. Cereal Chemistry 63: 411–413.Google Scholar
Riales, R. and Albrink, M. J. 1981. Effect of chromium chloride supplementation on glucose tolerance and serum lipids including high density lipoproteins of adult men. American Journal of Clinical Nutrition 34: 2670–2678.CrossRefGoogle ScholarPubMed
Rosebrough, R. W. and Steele, N. C. 1981. Effects of supplemental dietary chromium or nicotinic acid on carbohydrate metabolism during basal, starvation, and refeeding periods in poults. Poultry Science 60: 407–417.Google Scholar
Schroeder, H. A. 1971. Losses of vitamins and trace minerals resulting from processing and preservation of foods. American Journal of Clinical Nutrition 24: 562–569.CrossRefGoogle ScholarPubMed
Schwartz, K. and Mertz, W. 1959. Chromium III and the glucose tolerance factor. Archives of Biochemistry and Biophysics 85: 292–295.Google Scholar
Simonoff, M., Llabador, Y., Hamon, C., Peers, A. M. and Simonoff, G. N. 1984. Low plasma chromium in patients with coronary artery and heart diseases. Biological Trace Element Research 6: 431–439.CrossRefGoogle ScholarPubMed
Statistical Analysis Systems Institute. 1987. SAS/STAT user’s guide, version 6·06, fourth edition. SAS Institute, Cary, NC.Google Scholar
Steele, N. C. and Rosebrough, R. W. 1981. Effect of trivalent chromium on hepatic lipogenesis by the turkey poult. Poultry Science 60: 617–622.Google Scholar
Stoecker, B. J., Li, Y. C., Wester, D. B. and Chan, S. B. 1987. Effects of Torula and Brewer’s yeast diet in obese and lean mice. Biological Trace Element Research 14: 249–254.Google Scholar
Walker, M. 1993. Chromium: the essential mineral. Health Foods Business 5: 51–52.Google Scholar
Wang, M. M., Fox, E. A., Stoecker, B. J., Menendez, C. E. and Chan, S. B. 1989. Serum cholesterol of adults supplemented with brewer’s yeast or chromium chloride. Nutrition Research 9: 989–998.Google Scholar
Ward, T. L., Berrio, L. F., Southern, L. L., Fernandez, J. M. and Thompson Jr, D. L. 1994. In-vivo and in-vitro evaluation of chromium tripicolinate on insulin binding in pig liver cell plasma membranes. FASEB Journal 8: A194.Google Scholar