Hostname: page-component-76fb5796d-dfsvx Total loading time: 0 Render date: 2024-04-25T16:02:54.095Z Has data issue: false hasContentIssue false
  • English
  • Français

Hypertensive Disorders in Twin Pregnancies

Published online by Cambridge University Press:  01 August 2014

W. Chaim ,
D. Fraser ,
M. Mazor  and
J. R. Leiberman
W. Chaim*
Affiliation:
Department of Obstetrics and Gynecology
D. Fraser
Affiliation:
Epidemiology and Health Services Evaluation Unit, Soroka Medical Center of Kupat Holim, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
M. Mazor
Affiliation:
Department of Obstetrics and Gynecology
J. R. Leiberman
Affiliation:
Department of Obstetrics and Gynecology
*
Department of Obstetrics and Gynecology, “Soroka Medical Center” P.O. Box 151, Beer-Sheva 84101, Israel

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

This study investigates the influence of hypertensive disorders on twin pregnancies for an unselected, population-based series. Between 1986 and 1991, out of a total of 56,381, 766 (1.3%) were twin deliveries at our institution, the only tertiary care hospital serving a population of about 400, 000 inhabitants. The incidence of hypertensive disorders was significantly higher in twin gestations than in singleton pregnancies, at 3437/55,615 (6.2%) vs 85/766 (11.1%) (p<0.001, OR=1.8, 95% CI =1.4-2.3). Hypertensive disorders were significantly higher in twin as compared to singleton pregnancies, regardless of parity, and even after adjusting for maternal age. More instrumentai or surgical deliveries were needed when pregnancies were complicated by hypertension, in twin as well as singleton gestations. Despite the association between prematurity and hypertensive disorders, and prematurity and perinatal mortality, no significant difference was found in perinatal mortality between hypertensive and nor-motensive twin pregnancies. The neonatal death-rate in normotensive and hypertensive twin pregnancies (3.7% and 3.5% respectively) was higher than that of stillbirths (respectively 2.3% and 0%).

Keywords

Twin pregnanciesHypertension
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 44 , Issue 1 , January 1995 , pp. 31 - 39
Copyright
Copyright © The International Society for Twin Studies 1995

References

REFERENCES

1.Blickstein, I, Ben-Hur, H, Borenstein, R (1992): Perinatal outcome of twin pregnancies complicated with preeclampsia. Am J Perinatol 9:258–60.Google Scholar
2.Campbell, DM (1990): Multiple pregnancy. Bailliere's Clin Obstet Gynecol 4:109–127.CrossRefGoogle ScholarPubMed
3.Corney, G, Seedburgh, D, Thompson, B, et al (1981): Multiple and singleton pregnancy: differences between mothers as well as offspring. In Twin Research 3: Twin Biology and Multiple Pregnancy. New York: Alan R. Liss, pp 107–114.Google Scholar
4.Creasy, RK, Resnik, R (1989): Maternal Fetal Medicine, 2nd Edition. Philadelphia: W.A. Saunders Company, p 582.Google Scholar
5.Herruzo, AJ, Martinez, L, Biel, E, et al (1991): Perinatal morbidity and mortality in twin pregnancies. Int J Gynecol Obstet; 36:17–22.Google Scholar
6.Leiberman, JR (1989): Vascular nature of pre-eclampsia. Med Hypotheses; 28:281–3.Google Scholar
7.Long, PA and Oats, JN. (1987): Pre-eclampsia in twin pregnancy - severity and pathogenesis. Aust NZ J Obstet Gynecol; 27:1–5.Google Scholar
8.MacGillivray, I (1977): Sodium and water balance in pregnancy hypertension - the role of diuretics. Clin Obstet Gynecol 4:459–561.Google Scholar