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Hypertensive Disorders in Twin Pregnancies

Published online by Cambridge University Press:  01 August 2014

W. Chaim*
Department of Obstetrics and Gynecology
D. Fraser
Epidemiology and Health Services Evaluation Unit, Soroka Medical Center of Kupat Holim, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
M. Mazor
Department of Obstetrics and Gynecology
J. R. Leiberman
Department of Obstetrics and Gynecology
Department of Obstetrics and Gynecology, “Soroka Medical Center” P.O. Box 151, Beer-Sheva 84101, Israel


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This study investigates the influence of hypertensive disorders on twin pregnancies for an unselected, population-based series. Between 1986 and 1991, out of a total of 56,381, 766 (1.3%) were twin deliveries at our institution, the only tertiary care hospital serving a population of about 400, 000 inhabitants. The incidence of hypertensive disorders was significantly higher in twin gestations than in singleton pregnancies, at 3437/55,615 (6.2%) vs 85/766 (11.1%) (p<0.001, OR=1.8, 95% CI =1.4-2.3). Hypertensive disorders were significantly higher in twin as compared to singleton pregnancies, regardless of parity, and even after adjusting for maternal age. More instrumentai or surgical deliveries were needed when pregnancies were complicated by hypertension, in twin as well as singleton gestations. Despite the association between prematurity and hypertensive disorders, and prematurity and perinatal mortality, no significant difference was found in perinatal mortality between hypertensive and nor-motensive twin pregnancies. The neonatal death-rate in normotensive and hypertensive twin pregnancies (3.7% and 3.5% respectively) was higher than that of stillbirths (respectively 2.3% and 0%).

Research Article
Copyright © The International Society for Twin Studies 1995



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