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The Acardiac Anomaly. New Case Reports and Current Status

Published online by Cambridge University Press:  01 August 2014

C. Kaplan  and
K. Benirschke
C. Kaplan
Affiliation:
Research Department, San Diego Zoo, San Diego, California
K. Benirschke*
Affiliation:
Research Department, San Diego Zoo, San Diego, California
*
Zoological Society of San Diego, PO Box 551, San Diego, CA 92112, USA

Abstract

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Two cases of holoacardius are presented. Both had a normal 46,XX female karyotype, identical to that of their respective cotwin. Data are presented supporting the concept that the placental vascular anastomoses are the primary agents in the formation of an acardiac. Cytogenetics, epidemiology and other theories of pathogenesis are discussed.

Keywords

HoloacardiusTwin placentaPlacental anastomosesAcardiac's karyotypePathogenesisOmphaloceleCardiac developmentTwinning
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 28 , Issue 1 , January 1979 , pp. 51 - 59
Copyright
Copyright © The International Society for Twin Studies 1979

References

REFERENCES

1.Alderman, B (1973): Foetus acardius amorphus. Postgrad Med J 49:102–105.CrossRefGoogle ScholarPubMed
2.Altshuler, G, Tsang, RG, Ermocilla, R (1975): Single umbilical artery: Correlation of clinical statusCrossRefGoogle Scholar
3.Arakaki, PT, Sparkes, RS (1963): Leukocyte chromosomes from culture of whole blood. Cytogenetics 2:57–60.Google Scholar
4.Averback, P, Wiglesworth, FW (1978): Congenital absence of the heart: Observations of human funiculopagous twinning with insertio funiculi furcata, fusion, forking and interpositio velamen-tosa. Teratology 17:143–150.CrossRefGoogle Scholar
5.Basrur, PK, Basrur, UR, Gilman, JPW (1963): A simple method of short-term cultures from small biopsies. Exp Cell Res 30:299–332.CrossRefGoogle ScholarPubMed
6.Benirschke, K (1959): Nuclear sex of holoacardii amorphi. Obstet Gynecol 14:72–76.Google Scholar
7.Benirschke, K, Driscoll, SG (1967): “The Pathology of the Human Placenta.” New York: Springer-Verlag.Google Scholar
8.Benirschke, K (1970): Spontaneous chimerism in mammals, a critical review. Curr Topics Pathol 51:1–61.Google Scholar
9.Benirschke, K, Hoefnagel, D (1970): Structural development of the placenta in relation to fetal growth. In Waisman, HA, Kerr, G (eds): “Fetal Growth and Development.” New York: McGraw-Hill.Google Scholar
10.Benirschke, K: In Bloor, CM (ed) (1972): “Prenatal Cardiovascular Adaptation in Comparative Pathophysiology of Circulatory Disturbances.” New York: Plenum.Google Scholar
11.Benirschke, K, Kim, CC (1973): Multiple pregnancy. J Engl J Med 288:1276–1284; 1329–1336.CrossRefGoogle ScholarPubMed
12.Benirschke, K, Des Roches Harper, V (1977): The acardiac anomaly. Teratology 15:311–316.Google Scholar
13.Boronow, RC, West, RH (1964): Monster acardius parasiticus. Am J Obstet Gynecol 88:233–237.Google Scholar
14.Dunn, HL, Lein, DH, Kenney, RM (1967): The cytologic sex of a bovine anidian (Amorphous) twin monster. Cytogenetics 6:412–419.CrossRefGoogle ScholarPubMed
15.Dunn, HO, Roberts, SJ (1972): Chromosome studies of a bovine acephalic-acardiac monster. The Cornell Veterinarian 62:425–431.Google Scholar
16.Frutiger, P (1969): Zum Problem der Akardie. Acta Anat (Basel) 74:505–531.CrossRefGoogle Scholar
17.Gruenwald, P (1942): Early human twins with peculiar relations to each other and the chorion. Anat Rec 83:267–279.Google Scholar
18.Herzog, VA, Rieck, GW (1969): Chromosomenanomalie bei einem Acardius (Amorphous globosus) vom Rind. Zuchthygiene 4:57–60.CrossRefGoogle Scholar
19.James, WH (1977): A note on the epidemiology of acardiac monsters. Teratology 16:211–216.Google Scholar
20.Ketchum, J, Motyloff, L (1957): Chorioangiopagus parasiticus (Schwalbe): Report of a case of acardius acephalus and a case of fetus amorphus. Am J Obstet Gynecol 73:1349–1354.CrossRefGoogle Scholar
21.Kyriazis, A, Arean, VM, Shanklin, DR (1974): Placental-radiographic analysis of parasitic acardiac fetus: Partially common umbilical circulation. J Reprod Med 12:74–81.Google Scholar
22.Melnick, M, Myrianthopoulos, NC (1976): Malformation in monozygotic twins: A possible example of environmental influence on the developmental genetic clock. Teratology 13:30a.Google Scholar
23.Monie, IW (1970): Genesis of single umbilical artery. Am J Obstet Gynecol 108:400–405.Google Scholar
24.Napolitani, F, Schreiber, I(1960): The acardiac monster: A review of the world literature and presentation of 2 cases. Am J Obstet Gynecol 80:582–589.Google Scholar
25.Osathanondh, R, Driscoll, SG, Naftolin, F (1975): Discordant severe cranial defects in monozygous twins. Am J Obstet Gynecol 122:301–305.Google Scholar
26.Paris Conference (1973): “Standardization in Human Genetics (1973).” BDOAS 8.7. New York: The National Foundation-March of Dimes.Google Scholar
27.Rashad, MN, Kerr, MG (1966): Observations on the so-called holoacardius amorphus. J Anat 100: 425–426.Google Scholar
28.Rehder, H, Geisler, M, Kleinbrecht, J, Degenhardt, KH (1978): Monozygotic twins with 47,XXY karyotype and discordant malformations. Teratology 17:50a.Google Scholar
29.Richart, R, Benirschke, K (1963): Holoacardius amorphus: Report of a case with chromosome analysis. Am J Obstet Gynecol 86:329–322.CrossRefGoogle ScholarPubMed
30.Rychter, L (1962): Experimental morphology of the aortic arches and heart loop in chick embryos. Adv Morphol 2:333–371.CrossRefGoogle Scholar
31.Sarma, V (1960): Holoacrdius monster in obstetrics. Br J Clin Pract 14:795–800.Google Scholar
32.Schatz, F (1898): “Die Acardii und ihre Verwandten.” Berlin: A. Hirschwald.Google Scholar
33.Scott, JM, Ferguson-Smith, MA (1973): Heterokaryotypic monozygotic twins and the acardiac monster. J Obstet Gynaecol Br Commonw 80:52–59.CrossRefGoogle ScholarPubMed
34.Seabright, M (1972): The use of proteolytic enzyme for the mapping of structural rearrangements in the chromosomes of man. Chromosoma 36:204–210.Google Scholar
35.Severn, CB, Holyoke, EA (1973): Human acardiac anomalies. Am J Obstet Gynecol 116:358–365.CrossRefGoogle ScholarPubMed
36.Simonds, JP, Gowen, GA (1925): Fetus amorphus, report of a case. Gynecol Obstet 41:171–179.Google Scholar
37.Svejda, J (1947): A case of foetus pseudoamorphus. J Pathol Bacteriol 59:647–655.Google Scholar
38.Turpin, RL, Bocquet, L, Grasset, J (1967): Etude d'un couple monozygote: Fille normale-monstre acardiaque féminin. Considérations anatomo-pathologiques et cytogénétiques. Ann Genet 10:107–113.Google Scholar
39.Willis, RA (1958): “The Borderland of Embryology and Pathology.” London: Butterworth.Google Scholar
40.Wylin, R (1971): Acardiac monster in a triplet pregnancy. J Reprod Med 6:270–273.Google Scholar