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Identification of genomic regions related to tenderness in Nellore beef cattle

Published online by Cambridge University Press:  03 October 2017

M. E. Carvalho ,
F. S. Baldi ,
M. H. A. Santana ,
R. V. Ventura ,
G. A. Oliveira ,
R. S. Bueno ,
M. N. Bonin ,
F. M. Rezende ,
L. L. Coutinho  and
J. P. Eler
...Show all authors
M. E. Carvalho*
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
F. S. Baldi
Affiliation:
Department of Animal Science, São Paulo State University, access way Paulo Donato Castellane s/n, Jaboticabal, SP, Brazil
M. H. A. Santana
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
R. V. Ventura
Affiliation:
Beef Improvement Opportunities, 294 Mill St East Suite 209 Elora, ON, Canada
G. A. Oliveira
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
R. S. Bueno
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
M. N. Bonin
Affiliation:
Embrapa Beef Cattle, Av. Radio Maia, 830 Campo Grande, MS, Brazil
F. M. Rezende
Affiliation:
College of Veterinary Medicine, Federal University of Uberlandia, Av. Para, 1720 Uberlandia, MG, Brazil
L. L. Coutinho
Affiliation:
Department of Animal Science, University of Sao Paulo, Av. Padua Dias, 11 Piracicaba, SP, Brazil
J. P. Eler
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
J. B. S. Ferraz
Affiliation:
College of Animal Science and Food Engineering, University of Sao Paulo, Duque de Caxias, 225 Pirassununga, SP, Brazil
*
†E-mail: minosec@gmail.com
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Abstract

The aim of this study was to identify genomic regions that associated with beef tenderness in Nellore cattle. Phenotypes were obtained according to the standard USDA Quality Grade (1999). Data from 909 genotyped Nellore bulls were used in the Genome-Wide Association Study (GWAS) undertaken using a single-step approach including also a pedigree file composed of 6276 animals. The analyses were performed using the Blupf90 software, estimating the effect of genomic windows of 10 consecutive markers. The GWAS results identified 18 genomic regions located on 14 different chromosomes (1, 4, 6, 7, 8, 10, 18, 19, 20, 21, 22, 25, 26 and 29), which explained more than 1% of the total additive genetic variance; several candidate genes were located in these regions including SLC2A9, FRAS1, ANXA3, FAM219A, DNAI, AVEN, SHISA7, UBE2S, CDC42EP5, CNTN3, C16orf96, UBALD1, MGRN1 and SNORA1 With the single-step GWAS, it was possible to identify regions and genes related to meat tenderness in Nellore beef cattle.

Keywords

BLUPF90Bos indicusGWASmeat qualityshear force
Type
Full Paper
Information
Advances in Animal Biosciences , Volume 8 , Supplement s1: Improving the quality and sustainability of beef production , October 2017 , pp. s42 - s44
Copyright
© The Animal Consortium 2017 

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