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Planting a misdiagnosis of Alzheimer's disease in a person's mind

Published online by Cambridge University Press:  24 June 2014

Harald Merckelbach*
Affiliation:
Faculty of Psychology and Neurosciences, Maastricht University, Maastricht, The Netherlands
Marko Jelicic
Affiliation:
Faculty of Psychology and Neurosciences, Maastricht University, Maastricht, The Netherlands
Cees Jonker
Affiliation:
Department of Psychiatry/Alzheimer Centre, VU University Medical Center, Amsterdam, The Netherlands
*
Dr Harald Merckelbach, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands. Tel: 043 3881945; Fax: 043-3884196; E-mail: H.Merckelbach@maastrichtuniversity.nl

Extract

Objective: There is an extensive corpus of knowledge about how misinformation may distort autobiographical memories. A diagnostic error can be conceptualised as a form of misinformation.

Methods: The authors discuss the case of a 58-year-old woman who was given a misdiagnosis of Alzheimer's disease.

Results: The patient was deeply convinced that the diagnosis was correct, even when she was confronted with contradictory evidence.

Conclusion: A diagnosis is not a neutral piece of information. It profoundly affects the lives of patients. The consequences of a misdiagnosis may be similar to persistent false memories.

Type
Case Report
Copyright
Copyright © Cambridge University Press 2011

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References

1.Loftus, EF.Our changeable memories: legal and practical implications. Nat Rev Neurosci 2003;4:231234.CrossRefGoogle ScholarPubMed
2.Ost, J, Costall, A, Bull, R.A perfect symmetry? A study of retractors' experiences of making and then repudiating claims of early sexual abuse. Psychol Crime Law 2002;8:155181.CrossRefGoogle Scholar
3.Rietveld, S, Brosschot, JF.Current perspectives on symptom perception in asthma: a biomedical and psychological review. Int J Behav Med 1999;6:120135.CrossRefGoogle ScholarPubMed
4.Jonker, C, Launer, LJ, Hooijer, C, Lindeboom, J.Memory complaints and memory impairment in older individuals. J Am Ger Soc 1996;44:4449.CrossRefGoogle ScholarPubMed
5.Wolf, SA, Henry, M, Deike, R, Ebert, AD, Wallesch, C-W.Verdachtsdiagnose Alzheimer-Demenz. Bei welchen Patienten erfolgt eine neuropsychologische Abklärung? [Suspected Alzheimer's disease. Selection of outpatients for neuropsychological assessment]. Nervenarzt 2008;79: 444453.CrossRefGoogle Scholar
6.Folstein, MF, Folstein, SE, McHugh, PR.Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiat Res 1975;12:189198.CrossRefGoogle Scholar
7.Hopman-Rock, M, Tak, ECPM, Staats, PGM.Development and validation of the observation list for early signs of dementia (OLD). Int J Geriatr Psychiatry 2001;16:406414.CrossRefGoogle ScholarPubMed
8.Larner, AJ.Getting it wrong: the clinical misdiagnosis of Alzheimer's disease. Int J Clin Pract 2004;58:10921104.CrossRefGoogle ScholarPubMed
9.Merckelbach, H, Jelicic, M, Pieters, M.The residual effect of feigning: how intentional faking may evolve into a less conscious form of symptom reporting. J Clin Exp Neuropsychol 2011;33:131139.CrossRefGoogle ScholarPubMed
10.Page, LA, Wessely, S.Medically unexplained symptoms: exacerbating factors in the doctor-patient encounter. J R Soc Med 2003;96:223227.CrossRefGoogle ScholarPubMed
11.Suhr, JA, Gunstad, J.Diagnosis threat: the effects of negative expectations on cognitive performance in head injury. J Clin Exp Neuropsychol 2002;24:448457.CrossRefGoogle ScholarPubMed