Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-18T19:26:04.707Z Has data issue: false hasContentIssue false
  • English
  • Français

A manic episode after bilateral subthalamic stimulation in a patient with advanced Parkinson's disease

Published online by Cambridge University Press:  01 August 2013

Isabel Claeys ,
Patrick Santens ,
Dirk Van den Abbeele ,
Dirk Van Roost  and
Gilbert MD Lemmens
Isabel Claeys*
Affiliation:
Department of Psychiatry, Ghent University Hospital, Ghent, Belgium
Patrick Santens
Affiliation:
Department of Neurology, Ghent University Hospital, Ghent, Belgium
Dirk Van den Abbeele
Affiliation:
Department of Psychiatry, Ghent University Hospital, Ghent, Belgium
Dirk Van Roost
Affiliation:
Department of Neurosurgery, Ghent University Hospital, Ghent, Belgium
Gilbert MD Lemmens
Affiliation:
Department of Psychiatry, Ghent University Hospital, Ghent, Belgium
*
Isabel Claeys, Department of Psychiatry, University Hospital Ghent, Ghent, Belgium Tel: 0032-(0)9/332.71.58; Fax: 0032-(0)9/260.35.00; E-mail: Isabel.Claeys@azmmsj.be
Get access Rights & Permissions [Opens in a new window]

Abstract

Deep brain stimulation (DBS) has proven to be an effective treatment for patients with refractory symptoms in the advanced stages of Parkinson's disease. However, different psychiatric and cognitive problems may occur after DBS. We report a case of a manic episode after DBS of the subthalamic nucleus in a patient with advanced Parkinson's disease. After slow and gradually restart of the neurostimulation using the lowest effective intensity, the motor symptoms remained sufficiently under control without causing any psychiatric problems.

Keywords

bilateral subthalamic stimulationmaniaParkinson's disease
Type
Case Report
Information
Acta Neuropsychiatrica , Volume 25 , Issue 6 , December 2013 , pp. 367 - 369
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Contarino, MF, Daniele, A, Sibilia, AHet al. Cognitive outcome 5 years after bilateral chronic stimulation of subthalamic nucleus in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 2007;78:248–252.CrossRefGoogle ScholarPubMed
2.Raucher-Chéné, D, Charrel, CL, Doe de Maindreville, A, Limosin, F. Manic episode with psychotic symptoms in a patient with Parkinson's disease treated by subthalamic nucleus stimulation: improvement on switching the target. J Neurol Sci 2008;273:116–117.CrossRefGoogle Scholar
3.Temel, Y, Kessels, A, Tan, S, Topdag, A, Boon, P, Visser-Vandewalle, V. Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism Relat Disord 2006;12:265–272.CrossRefGoogle ScholarPubMed
4.Romito, LM, Albanese, A. Dopaminergic therapy and subthalamic stimulation in Parkinson's disease: a review of 5 year reports. J Neurol 2010;257(Suppl. 2):S298–S304.CrossRefGoogle ScholarPubMed
5.Krack, P, Batir, A, Van Blercom, Net al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003;349:1925–1934.CrossRefGoogle ScholarPubMed