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Neurologic and psychiatric symptoms following chronic phenytoin intoxication

Published online by Cambridge University Press:  18 September 2015

J.A.J. Boermans*
Dept. of Psychiatry, Sint Maartens Gasthuis, Venlo; the Netherlands
JR. Nijdam
Vincent van Gogh Instituut Venray, the Netherlands
Dept. of Psychiatry, Sint Maartens Gasthuis, P.O. Box 1926, 5900 BX Venlo, The Netherlands


Reported (ir)reversibility of neurological and psychiatric symptoms induced by Phenytoin intoxication is being discussed by means of a case report concerning a 40-year old man who sets fire to his house during a psychosis. Observation after admission to a general psychiatric hospital, following a short period of detention, leads to diagnosing neurological and psychiatric symptoms due to chronic Phenytoin intoxication. Discontinuation of Phenytoin supply induces partial remission of the symptoms. Literature on the subject is being revised.

Copyright © Scandinavian College of Neuropsychopharmacology 2000

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