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This fully-updated third edition provides a practical and concise guide to all aspects of the perioperative care of cardiac surgical patients. Produced by recognised leaders from world-renowned cardiac centres, this is the authoritative text for residents and fellows in anaesthesia and cardiac surgery, clinical perfusionists, and critical care nurses. Updated chapters include regional anesthesia, paediatric cardiac anaesthesia, and anaesthesia for specific procedures such as aortic valve surgery and cardiac transplantation. An entire section is dedicated to transoesophageal echocardiography (TOE) in recognition of the increasing demand for basic TOE training. The book also includes an expanded chapter on the applications and anaesthetic implications of extracorporeal membrane oxygenation (ECMO). The text focuses on clinical practice and the basic science and pharmacology underpinning cardiac anaesthesia, ensuring the reader can easily apply the knowledge gained to real-life situations.
In recent years, there have been no books published on paediatric cardiac pathology despite enormous developments in genetics, a marked explosion of paediatric transplant programmes, surges in knowledge of fetal cardiac pathology and understanding of congenital heart disease, and the emergence of a flourishing cardiac imaging discipline. This book will be the first unified and comprehensive source of reference for childhood heart disease, covering the full field of paediatric cardiac pathology, in one volume. Comprising the twenty-five year experience of a single pathologist, the full spectrum of the pathology of heart disease, from the fetus to the adult, is uniquely presented here. Richly illustrated, with over 800 colour photographs, general and paediatric pathologists alike will be able to examine the microscopic features of the conditions described, with a specific focus on metabolic disease for practitioners worldwide.
Mathematical and numerical modelling of the human cardiovascular system has attracted remarkable research interest due to its intrinsic mathematical difficulty and the increasing impact of cardiovascular diseases worldwide. This book addresses the two principal components of the cardiovascular system: arterial circulation and heart function. It systematically describes all aspects of the problem, stating the basic physical principles, analysing the associated mathematical models that comprise PDE and ODE systems, reviewing sound and efficient numerical methods for their approximation, and simulating both benchmark problems and clinically inspired problems. Mathematical modelling itself imposes tremendous challenges, due to the amazing complexity of the cardiovascular system and the need for computational methods that are stable, reliable and efficient. The final part is devoted to control and inverse problems, including parameter estimation, uncertainty quantiﬁcation and the development of reduced-order models that are important when solving problems with high complexity, which would otherwise be out of reach.
Most patients with critical cardiac or thoracic conditions will at some stage pass through the cardiothoracic critical care unit. Critical care presents more complex clinical data than any other area of medicine. The new edition of Core Topics in Cardiothoracic Critical Care focuses on the latest practise in the management of patients in cardiothoracic intensive care. The practice of cardiothoracic critical care medicine is constantly evolving, and this new edition reflects the modernized learning styles for trainees. Each chapter includes key learning points as well as sample multiple choice questions and answers to assist in exam preparation. This edition also features updated chapters on ECMO, perioperative management of patients undergoing emergency cardiothoracic surgery, and advanced modes of organ support for patients. This text provides key knowledge in a concise and accessible manner for trainees, clinicians and consultants from specialities and disciplines such as cardiology and anaesthesia, and nursing and physiotherapy.
Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists and ultrasonographers.
Cardiopulmonary Bypass, 2nd edition, offers a complete introduction to this specialist technique for medical and technical personnel involved in extracorporeal cardiopulmonary support. A clinically based overview of the subject is provided and updated chapters incorporate the most current developments in the field. Introductory chapters cover equipment and preparation of the cardiopulmonary bypass machine, safety and monitoring, routine conduct of bypass, and the process of weaning from mechanical to physiological circulation. Specialist chapters on mechanical support, ECMO, special surgical procedures, blood conservation techniques, and particular medical conditions that affect the conduct of cardiopulmonary bypass are also included. This new edition includes self-assessment multiple choice questions at the end of each chapter, allowing readers to test their own understanding of the material. Written and edited by specialists from leading cardiac centres in the UK and USA, this is an invaluable resource for clinical perfusion scientists, cardiac surgeons and cardiothoracic anaesthetists in training.
The revised fourth edition of this classic textbook on cardiac anatomy written from the stance of the cardiac surgeon features many new images, including computed tomography angiography. The provision of multiple high quality surgical and pathological photographs makes it essential reading for cardiac surgeons, and of great value to cardiologists, surgical pathologists, radiologists and anaesthetists. The book will also be a valuable reference resource for any healthcare professional or researcher who needs to understand detailed cardiac anatomy. The book begins by describing the surgical approaches to the heart. It goes on to discuss the normal surgical anatomy of the cardiac chambers, the valves, and the systems for circulation and conduction within the heart. This provides the essential anatomical information required to assess and interpret the malformations, lesions and abnormalities discussed in the remainder of the book.
Postgraduate Vascular Surgery is your concise pocket guide to the FRCS and MRCS exams. Covering the full range of surgical interventions, including diagnosis, management, clinical investigation and treatment, all chapters have been written by specialists in their field. The chapters are structured with key bullet points for easy reference, as well as tables, figures and charts to aid understanding. Relevant references are included for further exploration of a particular topic. Tips and tricks on passing the exam are included. This book is aimed at candidates for the FRCS and intercollegiate MRCS exams, surgical trainees and those following a sub-speciality of vascular surgery.
It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.
This concise and informative textbook is aimed at trainee doctors beginning work on a stroke unit or residents embarking on their postdoctoral training in stroke care. It has a practical approach covering all important issues of prevention, diagnosis and treatment of cerebrovascular diseases. Chapters on the basics of neuropathology and pathophysiology are followed by reviews of clinical issues, including neuroimaging, clinical assessment, diagnosis and treatment, stroke in the young, and stroke-related dementia. Topics of rising importance are covered in chapters on stroke unit management, monitoring and management of complications including infections, recommendations for thrombolysis, interventions and neurosurgical procedures, and clear and balanced recommendations for secondary prevention. Finally, neuropsychological syndromes are explained and an up-to-date view on neurorehabilitation is presented. The authors are all experts in their field and many of them teach on the European Master's Program on Stroke Medicine, which is supported and endorsed by the European Stroke Organization.
Cardiopulmonary Bypass provides a practical overview of all aspects of clinical perfusion, giving core knowledge and essential background information for those early in their clinical training as well as more specialist information on key areas of clinical practice. Introductory chapters cover equipment and preparation of the cardiopulmonary bypass circuit, routine conduct of bypass, metabolic and hematological management during bypass and weaning from mechanical to physiological circulation. The effect of extracorporeal circulation on the body is described, and separate chapters detail the pathophysiology of the brain and kidney, two major sources of morbidity, in the peri-operative period. Specialist chapters on Mechanical Support, ECMO and Deep Hypothermic Circulatory Arrest are also included. Edited by expert cardiac anesthetists from Papworth Hospital, UK and the Mayo Clinic, USA, and with contributions from leading perfusionists and anesthetists, Cardiopulmonary Bypass is an invaluable practical manual for any clinical perfusionist, anesthetist or surgeons managing bypass.
A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.
Cardiac Arrest is the definitive and most comprehensive reference in advanced life support and resuscitation medicine. This new edition brings the reader completely up-to-date with developments in the field, focusing on practical issues of decision making, clinical management and prevention, as well as providing clear explanations of the science informing the practice. The coverage includes information on the latest pharmacotherapeutic options, the latest chest compression techniques and airway management protocols, all backed by clearly explained, evidence-based scientific research. The content is consistent with the latest guidelines for practice in this area, as detailed by the major international governing organisations. This volume is essential reading for all those working in the hospital environments of emergency medicine, critical care, cardiology and anesthesia, as well as those providing care in the pre-hospital setting, including paramedics and other staff from the emergency services.
Transoesophageal Echocardiography (TOE/TEE) in cardiac patients is now almost routine. Its use in cardiac monitoring has also extended to include critically ill patients for non-cardiac surgery and the intensive care setting. Specific accreditation is required prior to practice of TOE/TEE involving a written examination and a documented logbook of experience. This book was specifically designed to help candidates pass the written exam and was structured around the syllabus. Providing a summary of all relevant information, this is an invaluable study aid. Lists of further reading material are provided with every topic, including guidelines and safety, cardiomyopathies, heart disease, haemodynamic calculations and many more. Each chapter ends with a series of exam-style questions for self-assessment. An extremely useful book for trainee anaesthetists, intensivists, trainee cardiologists and cardiac surgeons.
Caring for Patients with Vascular Disease: A Practical Approach for Medical and Nursing Staff offers a step-by-step guide to caring for patients in a variety of clinical settings. It follows a patient's path of care from management in the outpatient clinic, through to the hospital ward, theatre, recovery room and back to the follow-up outpatient clinic. A clear, concise format is used throughout the book, with reference to evidence-based interventions and the physiology underpinning them, and the use of simple line diagrams and treatment flow charts to illustrate the essential aspects of care. Edited by a vascular nurse and vascular surgeon, with contributions from a group of invited authors, the book reflects the multidisciplinary nature of patient care and will be a valuable resource for nurses, surgeons and other healthcare professionals involved in caring for this patient group.
This book provides a detailed account of the principles and practice of contemporary lung transplantation. An accomplished, international team of contributing authors have combined their expertise to provide scientific developments and clinical knowledge based on their extensive experience. The book covers pulmonary vascular and parenchymal lung disease, which necessitate transplantation, together with all aspects of the multidisciplinary management of lung transplant patients. It concludes by looking at future developments in the treatment of advanced respiratory failure. This multidisciplinary approach makes the publication suitable for several subspecialities in addition to pulmonary medicine and lung transplantation, including haematology, radiology and clinical psychology. It will serve as a valuable source of reference and practical information for medical specialists in transplantation and all those working in thoracic organ transplant units.
Vascular biology is an exciting and rapidly advancing area of medical research, with many new and emerging pathophysiological links to an increasing number of diseases. This updated and expanded new edition takes full account of these developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account of vascular biology before leading on to explain mechanisms involved in disease processes. Other emerging topics include the role of nitric oxide and apoptosis in vascular biology. The breadth and range of subjects covered in this new edition do full justice to this increasingly important area of clinical research and medicine. This multidisciplinary approach will suit the needs of all those seeking to refresh their knowledge with the very latest advances from basic science through to clinical practice.
This 2001 book provides a practical and systematic approach to the acquisition, interpretation, and reporting of physiologic responses to exercise. Pulmonologists, cardiologists, and sports physicians, as well as respiratory therapists and other allied health professionals will find this book an indispensable resource when learning to select proper instruments, identify the most appropriate test protocols, and integrate and interpret physiologic response variables. The final chapter presents clinical cases to illuminate useful strategies for exercise testing and interpretation. Useful appendices offer laboratory forms, algorithms and calculations, as well as answers to FAQs. A glossary of terms, symbols, and definitions is also included. Exercise Testing and Interpretation: A Practical Approach offers clearly defined responses (both normal and abnormal) to over thirty performance variables including aerobic, cardiovascular, ventilatory, and gas-exchange variables. Practical, portable, and easy-to-read, this essential guidebook can be used as a complement to more detailed books on the topic, or stand on its own.
This book is a unique overview of cardiovascular development from the cellular to the organ level across a broad range of species. The first section focuses on the molecular, cellular, and integrative mechanisms that determine cardiovascular development. The second section has eight chapters that summarise cardiovascular development in invertebrate and vertebrate systems. The third section discusses the effects of disease and environmental and morphogenetic influences on non-mammalian and mammalian cardiovascular development. It includes strategies for the management of congenital cardiovascular malformations in utero and postnatally. The book will interest graduate students and researchers who work in the fields of developmental biology, physiology, and molecular and paediatric cardiology.
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