Book contents
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Chapter 7 Drugs to Treat Depression
- Chapter 8 Drugs to Treat Anxiety and Insomnia
- Chapter 9 Drugs to Treat Schizophrenia and Psychosis (Dopamine Antagonists and Partial Agonists Other Than Clozapine)
- Chapter 10 Clozapine
- Chapter 11 Lithium
- Chapter 12 Anticonvulsants for Mental Disorders: Valproate, Lamotrigine, Carbamazepine and Oxcarbazepine
- Chapter 13 Drugs to Treat Attention Deficit Hyperactivity Disorder (ADHD)
- Chapter 14 Drugs to Treat Dementia
- Chapter 15 Drugs to Treat Substance Use Disorders
- Chapter 16 Electroconvulsive Therapy and Neuromodulation Therapies
- Part 3 Specific Therapeutic Areas
- Index
- References
Chapter 9 - Drugs to Treat Schizophrenia and Psychosis (Dopamine Antagonists and Partial Agonists Other Than Clozapine)
from Part 2 - Psychopharmacology of the Main Psychotropic Drug Groups
Published online by Cambridge University Press: 29 May 2020
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Chapter 7 Drugs to Treat Depression
- Chapter 8 Drugs to Treat Anxiety and Insomnia
- Chapter 9 Drugs to Treat Schizophrenia and Psychosis (Dopamine Antagonists and Partial Agonists Other Than Clozapine)
- Chapter 10 Clozapine
- Chapter 11 Lithium
- Chapter 12 Anticonvulsants for Mental Disorders: Valproate, Lamotrigine, Carbamazepine and Oxcarbazepine
- Chapter 13 Drugs to Treat Attention Deficit Hyperactivity Disorder (ADHD)
- Chapter 14 Drugs to Treat Dementia
- Chapter 15 Drugs to Treat Substance Use Disorders
- Chapter 16 Electroconvulsive Therapy and Neuromodulation Therapies
- Part 3 Specific Therapeutic Areas
- Index
- References
Summary
This chapter provides a wide-ranging review of the clinical pharmacology of drugs for the treatment of schizophrenia and psychosis other than clozapine. These are dopamine receptor antagonists and dopamine partial agonists (as per the new Neuroscience-based Nomenclature (NbN) classification). This chapter covers their pharmacodynamics, pharmacokinetics, adverse effects, the latest evidence regarding their ‘antipsychotic’ mechanism of action, their use in the acute and maintenance treatment of schizophrenia, other therapeutic indications and some controversies that surround their use.Dopamine receptor antagonists and dopamine partial agonists are commonly referred to as antipsychotics. As a clinical shorthand the term ‘antipsychotic’ is likely to remain in use.
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- Seminars in Clinical Psychopharmacology , pp. 290 - 325Publisher: Cambridge University PressPrint publication year: 2020
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