The mediastinum is an anatomical area of great interest to pathologists, pulmonologists, radiologists, thoracic surgeons, and oncologists as it can be the site of origin of a surprisingly large number of neoplastic and non-neoplastic conditions. The two editors and several other surgical pathologists with many years of experience in the diagnosis of thymic neoplasms, malignant mesothelioma, soft tissue lesions, lymphomas, cardiac lesions, and other mediastinal lesions have collaborated with a multidisciplinary team of physicians that includes an experienced thoracic surgeon, cardiac pathologists, radiologists, and a clinical pathologist to provide a comprehensive review of mediastinal pathology.

The book includes a review of the anatomy of the mediastinum and its various structures and a concise yet informative discussion of the diagnosis of various mediastinal lesions by imaging methods. The embryology, anatomy, and pathophysiology of the thymus are reviewed in detail, followed by a comprehensive and well-illustrated description of the various non-neoplastic conditions that can arise in the thymus.