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Chapter 20 - Adjuncts for Ovarian Stimulation

from Section 4 - Non-conventional Forms Used during Ovarian Stimulation

Published online by Cambridge University Press:  14 April 2022

By
Alexander M. Quaas  and
David R. Meldrum
Edited by
Mohamed Aboulghar  and
Botros Rizk
Mohamed Aboulghar
Affiliation:
University of Cairo IVF Centre
Botros Rizk
Affiliation:
University of South Alabama
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Summary

Clomiphene (clomifene) citrate (CC) and follicle-stimulating hormone (FSH) have traditionally been considered the two main modalities used for ovarian stimulation (OS). However, many adjuncts have been used to maximize the convenience and effectiveness of these two agents, often specifically targeted to subsets of women undergoing stimulation. Most of these adjuncts are not officially approved for these indications. Therefore, educators and practitioners must take it upon themselves to assess the evidence supporting their use, and make treatment recommendations and decisions accordingly. We have outlined in an editorial in Fertility and Sterility a process to aid in this endeavor [1]. Decisions are based not only on randomized clinical trials (RCT), but also on other basic science and clinical evidence supporting their use.

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Chapter
Information
Ovarian Stimulation , pp. 189 - 198
Publisher: Cambridge University Press
Print publication year: 2022

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