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Chapter 55 - Thyroid Disease in Pregnancy

from Section 10 - Endocrine Disorders in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Michael A. Tsoukas ,
Ji Wei Yang  and
Amira El-Messidi
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

A 29-year-old primigravida is referred by her primary care provider to your tertiary center’s high-risk obstetrics unit for preconception counseling for known Graves’ disease.

Keywords

Preconception counselingGraves’ disease, pregnancyClinical manifestationsComorbiditiesInvestigationsTreatment, therapeutics, propylthiouracil, methimazole, carbimazole, radioiodine, toxicityThyroidectomyPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeAntepartum, intrapartum, postpartum managementThyroid stormPostpartum thyroiditisHypothyroidism
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 705 - 717
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

Alexander, EK, Pearce, EN, Brent, GA, et al. 2017. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017;27(3):315–389. [Correction in Thyroid. 2017 Sep;27(9):1212]CrossRefGoogle ScholarPubMed
Illouz, F, Luton, D, Polak, M, et al. Graves’ disease and pregnancy. Ann Endocrinol (Paris). 2018;79(6):636–646.CrossRefGoogle ScholarPubMed
Spencer, L, Bubner, T, Bain, E, et al. Screening and subsequent management for thyroid dysfunction pre-pregnancy and during pregnancy for improving maternal and infant health. Cochrane Database Syst Rev. 2015;(9):CD011263.CrossRefGoogle Scholar
Okosieme, OE, Khan, I, Taylor, PN. Preconception management of thyroid dysfunction. Clin Endocrinol (Oxf). 2018;89(3):269–279.CrossRefGoogle ScholarPubMed
Lazarus, PN JH. Hypothyroidism in pregnancy. Endocrinol Metab Clin North Am. 2019;48(3):547–556.Google Scholar
Thyroid disease in pregnancy: ACOG Practice Bulletin No. 223. Obstet Gynecol. 2020;135(6):e261–e274.CrossRefGoogle Scholar
Wright, HV, Williams, DJ. Thyrotoxicosis in pregnancy. Fetal and Maternal Medicine Review 2013; 24:2 108–128.CrossRefGoogle Scholar

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