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Neuro-behavioral Manifestations of Prader-Willi Syndrome
  • Edited by Deepan Singh, Maimonides Medical Center in Brooklyn
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Book description

The behavioral issues experienced by individuals with Prader-Willi Syndrome (PWS) can be both surprising and overwhelming to clinicians and caregivers. Despite the distress and dysfunction posed by them, there are very few resources available to address these neuropsychiatric problems. This invaluable guidebook helps to identify and address the spectrum of behavioral issues faced by individuals with PWS. Written by a psychiatrist with unique expertise in the management of patients with this condition, this easy-to-read book explores practical details that will aid any clinician or caregiver. Chapters offer vivid case examples and clear guidance on both the behavioral and pharmacological management of issues such as anxiety, skin-picking, ADHD, disruptive behavior (including non-suicidal self-harm), mood disorders (including depression and bipolar disorder), and psychosis. Neuro-behavioral Manifestations of Prader-Willi Syndrome serves as an essential and practical companion for any caregiver or healthcare professional providing care to people with PWS.


‘Prader-Willi syndrome (PWS) is more than just a rare genetic disorder. It is a complex syndrome with many challenging symptoms. Dr Singh not only names and describes these symptoms, he also provides practical recommendations for managing them. This book covers the spectrum of common behavioral problems seen in PWS in terms and language people without medical training can understand, and it delves deeper into the neuro-behavioral manifestations aimed at medical professionals who will care for patients with PWS. This book is a great reference tool for everyone from families who have just received their diagnosis to caregivers of older children experiencing many of these behaviors to medical professionals who will counsel these patients, parents and caregivers.’

Paige Rivard - MBA, CEO Prader-Willi Syndrome Association, USA

'The Neuro-behavioral Manifestations of Prader-Willi Syndrome provides an in-depth look at those aspects of PWS that families struggle with every day. From anxiety to behavioral outbursts to frank mental illness, Dr Singh and colleagues provide insight and a holistic approach to managing some of the most difficult aspects of the syndrome. The chapters are written with sufficient detail to be highly informative for clinicians and health care providers who wish to become more knowledgeable about PWS, while the ‘Note to Caregiver’ section in each chapter will be particularly helpful for families. This book is bound to be an important and well-used resource for anyone caring for a person with PWS.'

Theresa V. Strong - Ph.D., Director of Research Programs, Foundation for Prader-Willi Research

‘In this book, Dr Deepan Singh, along with other contributors, has set out his perspective as a psychiatrist seeing people with PWS in the context of the American health system. I admire his commitment seeking to cover this complex area in these 15 chapters, which range widely in their content including topics as diverse as caregiver burden and the neurobiology of PWS. Importantly, Dr Singh draws upon particular areas of psychiatric knowledge applying them to our understanding of PWS.’

Anthony Holland - Emeritus Professor, Department of Psychiatry, University of Cambridge, UK

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  • Chapter 1 - Knowing Your Patient
    pp 1-7
  • A Biopsychosocial Perspective


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