Skip to main content Accessibility help
  • Print publication year: 2021
  • Online publication date: January 2021

Chapter 5 - Brain Imaging of Reward Dysfunction in Unipolar and Bipolar Disorders

from Section 3 - Functional and Neurochemical Brain Studies


In recent years, there has been tremendous support for working toward the RDoC goals of identifying the neurobiological mechanisms that cut across or are common to multiple psychiatric disorders. Identifying the pathophysiological mechanisms underlying transdiagnostic symptoms will improve the validity of disease classifications by grouping individuals based on multiple dimensions of behavior and biology. This could potentially account for heterogeneity and comorbidity observed among DSM diagnostic categories.