Skip to main content Accessibility help
×
Hostname: page-component-8448b6f56d-sxzjt Total loading time: 0 Render date: 2024-04-16T07:34:11.263Z Has data issue: false hasContentIssue false

Chapter 6 - Natural Hormone Replacement Therapy after Menopause by Ovarian Tissue Transplantation

Published online by Cambridge University Press:  18 June 2020

Nicholas Panay
Affiliation:
Queen Charlotte's & Chelsea Hospital, London
Paula Briggs
Affiliation:
Liverpool Women's NHS Foundation Trust
Gabor T. Kovacs
Affiliation:
Monash University, Victoria
Get access

Summary

During fetal life, 100–2000 primordial germ cells enter a massive proliferation process and, by mid-gestation, there are several million potential oocytes. However, most (85 per cent) of them are lost prior to birth [38] (Figure 6.1).

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American College of Physicians. Guidelines for counseling postmenopausal women about preventive hormone therapy. Ann Intern Med 1992;117:1038–41.Google Scholar
Amundsen, DW, Diers, CL. The age of menopause in classical Greece and Rome. Hum Biol 1970;42:79.Google Scholar
Amundsen, DW, Diers, CL. The age of menopause in medieval Europe. Hum Biol 1973;45:605.Google Scholar
Andersen, CY, Kristensen, SG. Novel use of the ovarian follicular pool to postpone menopause and delay osteoporosis. Reprod Biomed Online 2015;31:128–31.Google Scholar
Andersen, CY, Kristensen, SG. Response: transplantation of ovarian tissue to postpone menopause – is it really more advantageous for women’s health than menopause hormone therapy? Reprod Biomed Online 2015;31:828.Google Scholar
Anderson, RA, Fauser, B. Ovarian tissue transplantation for hormone replacement. Reprod Biomed Online 2018;37(3):251–2.Google Scholar
Bjelland, EK, et al. Is unilateral oophorectomy associated with age at menopause? A population study (the HUNT2 Survey). Hum Reprod 2014;29:835–41.Google Scholar
Callejo, J, et al. Long-term ovarian function evaluation after autografting by implantation with fresh and frozen-thawed human ovarian tissue. J Clin Endocrinol Metab 2001;86:4489–94.Google Scholar
Clemons, M, Goss, P. Estrogen and the risk of breast cancer. N Engl J Med 2001;344:276–85.Google Scholar
Damásio, LC, et al. Heterotopic ovarian transplantation results in less apoptosis than orthotopic transplantation in a minipig model. J Ovarian Res 2016;9:14.Google Scholar
Demeestere, I, et al. Orthotopic and heterotopic ovarian tissue transplantation. Hum Reprod 2009;15:649–55.Google Scholar
Donnez, J, et al. Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease. Fertil Steril 2012;98:720–5.Google Scholar
Donnez, J, Dolmans, MM. Fertility preservation. Nat Rev Endocrinol 2013;9:735–49.Google Scholar
Donnez, J, Dolmans, MM. Fertility preservation in women. N Eng J Med 2017;26:1657–65.Google Scholar
Donnez, J, Dolmans, MM. The ovary from conception to death Fertil Steril 2017;108:594–595.Google Scholar
Donnez, J, Dolmans, MM. Natural hormone replacement therapy with a functioning ovary after the menopause: dream or reality? Reprod Biomed Online 2018;37:359–66.Google Scholar
Kim, SS. Assessment of long-term endocrine function after transplantation of frozen-thawed human ovarian tissue to the heterotopic site: 10 year longitudinal follow-up study. J Assist Reprod Genet 2012;29:489–93.Google Scholar
Kim, SS. Revisiting the role of heterotopic ovarian transplantation: futility or fertility. Reprod Biomed Online 2014;28:141–5.Google Scholar
Kiran, G, et al. Ovarian cortical transplantation may be an alternative to hormone therapy in patients with early climacterium. Fertil Steril 2005;84:1509.Google Scholar
Lass, A. Women with one ovary have decreased response to GnRHa/HMG ovulation protocol in IVF but the same pregnancy rate as women with two ovaries. Hum Reprod 1997;12:298300.Google Scholar
Lee, DM, et al. Subcutaneous ovarian tissue transplantation in nonhuman primates: duration of endocrine function and normalcy of subsequent offspring as demonstrated by reproductive competence, oocyte production, and telomere length. J Assist Reprod Genet 2017;34:1427–34.Google Scholar
Liu, L, Keefe, DL. Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice. Hum Reprod 2002;17:267–85.Google Scholar
Liu, JP, Li, H. Telomerase in the ovary. Reproduction 2010;140:215–22.Google Scholar
Lobo, RA. Where are we 10 years after the Women’s Health Initiative? J Clin Endocrinol Metab 2013;98:1771–80.Google Scholar
Lobo, RA. Reproductive endocrinology: don’t be so quick to stop hormone-replacement therapy. Nat Rev Endocrinol 2016;12:11–33.Google Scholar
Lobo, RA, et al. Back to the future: hormone replacement therapy as part of a prevention strategy for women at the onset of menopause. Atherosclerosis 2016;254:282–90.Google Scholar
Lobo, RA. Hormone-replacement therapy: current thinking. Nat Rev Endocrinol 2017;13:220–31.Google Scholar
Manavella, DD, et al. Adipose tissue-derived stem cells in a fibrin implant enhance neovascularization in a peritoneal grafting site: a potential way to improve ovarian tissue transplantation. Hum Reprod 2018;1(33):270–9.Google Scholar
Patrizio, P, Caplan, AL. Forever young? The ethical challenges of using ovarian tissue transplants to treat menopause. Reprod Biomed Online 2015;31:132–3.Google Scholar
Rosendahl, M, et al. Biochemical pregnancy after fertilization of an oocyte aspirated from a heterotopic autotransplant of cryopreserved ovarian tissue: case report. Hum Reprod 2006;21:2006–9.Google Scholar
Rossouw, JE, Writing Group for the Women’s Health Initiative Investigators, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002;288:321–33.Google Scholar
Sitruk-Ware, R. New hormonal therapies and regimens in the postmenopause: routes of administration and timing of initiation. Climacteric 2007;10:358–70.Google Scholar
Smith, DW, Bradshaw, BS. Variation in life expectancy during the twentieth century in the United States. Demography 2006;43:647–57.Google Scholar
Stern, CJ, et al. First reported clinical pregnancy following heterotopic grafting of cryopreserved ovarian tissue in a woman after a bilateral oophorectomy. Hum Reprod 2013;28:2996–9.Google Scholar
Stern, CJ, et al. Delivery of twins following heterotopic grafting of frozen-thawed ovarian tissue. Hum Reprod 2014;29:1828.Google Scholar
Suzuki, N, et al. Assessment of long-term function of heterotopic transplants of vitrified ovarian tissue in cynomolgus monkeys. Hum Reprod 2012;27:2420–9.Google Scholar
von Wolff, M, et al. Transplantation of ovarian tissue to postpone menopause – is it really more advantageous for women’s health than menopause hormone therapy? Reprod Biomed Online 2015;31:827.Google Scholar
Wallace, WH, Kelsey, TW. Human ovarian reserve from conception to menopause. Plos ONE 2010;5:e8772.Google Scholar
Yasui, T, et al. Factors associated with premature ovarian failure, early menopause and earlier onset of menopause in Japanese women. Maturitas 2012;72:249.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×