Contents

pp v-ix

List of contributors

pp x-xii

Foreword by Constance Weinstein

pp xiii-xiv

Introduction: Why study cardiovascular development?

pp 1-4

Part I - Molecular, cellular, and integrative mechanisms determining cardiovascular development

pp 5-6

1 - Genetic dissection of heart development

pp 7-17

2 - Cardiac membrane structure and function

pp 18-26

3 - Development of the myocardial contractile system

pp 27-34

4 - Vasculogenesis and angiogenesis in the developing heart

pp 35-42

5 - Extracellular matrix maturation and heart formation

pp 43-56

6 - Endothelial cell development and its role in pathogenesis

pp 57-64

7 - Embryonic cardiovascular function, coupling, and maturation: A species view

pp 65-87

8 - Hormonal systems regulating the developing cardiovascular system

pp 88-98

Part II - Species diversity in cardiovascular development

pp 99-100

9 - Evolution of cardiovascular systems: Insights into ontogeny

pp 101-113

10 - Morphogenesis of vertebrate hearts

pp 114-126

11 - Invertebrate cardiovascular development

pp 127-144

12 - Piscine cardiovascular development

pp 145-165

13 - Amphibian cardiovascular development

pp 166-182

14 - Reptilian cardiovascular development

pp 183-192

15 - Avian cardiovascular development

pp 193-210

16 - Mammalian cardiovascular development: Physiology and functional reserve of the fetal heart

pp 211-224

Part III - Environment and disease in cardiovascular development

pp 225-226

17 - Oxygen, temperature, and pH influences on the development of nonmammalian embryos and larvae

pp 227-239

18 - Modeling gas exchange in embryos, larvae, and fetuses

pp 240-258

19 - Principles of abnormal cardiac development

pp 259-267

20 - In utero and postnatal interventions for congenital cardiovascular malformations

pp 268-280

21 - Applying the science of cardiovascular development to congenital cardiovascular malformations

pp 281-284

Epilogue: Future directions in developmental cardiovascular sciences

pp 285-286