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19 - Perspective for new pharmacological interventions

Published online by Cambridge University Press:  05 May 2016

Jair C. Soares
Affiliation:
University of Texas Health Science Center, Houston
Allan H. Young
Affiliation:
King's College London
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Summary

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Chapter
Information
Bipolar Disorders
Basic Mechanisms and Therapeutic Implications
, pp. 250 - 255
Publisher: Cambridge University Press
Print publication year: 2016

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References

Altman, E.G., Hedeker, D.R., Janicak, P.G., et al. The clinician-administered rating scale for mania (CARS-M): development, reliability, and validity. Biol Psychiatry. 1994;36:124–3l.CrossRefGoogle ScholarPubMed
Boadie, W.D., Thase, M.E., Wun, C.C., et al. A meta-analysis of factors impacting detection of antidepressant efficacy in clinical trials: the importance of academic sites. Neuropsychopharmacology. 2012;17:2.Google Scholar
Bowden, C. L., Strategies to reduce misdiagnosis of bipolar depression. Psychiatr Serv2001;52(1):51–5.CrossRefGoogle ScholarPubMed
Bowden, C.L. Bipolar pathophysiology and development of improved treatments. Review and recommendations for innovative studies. Brain Res. 2008;1235:92–7.CrossRefGoogle Scholar
Bowden, C.L., Brugger, A.M., Swann, A.C., et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. JAMA. 1994;271:918–24.CrossRefGoogle ScholarPubMed
Bowden, C.L., Calabrese, J.R., McElroy, S.L., et al. A randomized, placebo-controlled 12 month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder Arch Gen Psychiatr. 2000;57:481–9.CrossRefGoogle ScholarPubMed
Bowden, C.L., Tohen, M., Mintz, J., et al. Development of novel integrative multistate measures of efficacy, tolerability and functional status in maintenance clinical trials for bipolar disorder. Annual Meeting of the ACNP, Kona, Hawaii, December 2011.Google Scholar
Calabrese, J.R., Bowden, C.L., McElroy, S.L., et al. Spectrum of activity of lamotrigine in treatment-refractory bipolar disorder. Am J Psychiatry. 1999;156:1019–23.CrossRefGoogle ScholarPubMed
Calabrese, J. R., Suppes, T., Bowden, C. L., et al. A double-blind placebo-controlled prophvlaxis study of lamotrigine in rapid cycling bipolar disorder. J Clin Psychiatry. 2000;61:841–50.CrossRefGoogle Scholar
Calabrese, J.R., Bowden, C.L., Sachs, G., et al. A placebo–controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder J Clin Psychiatr. 2003;64:1013–24.CrossRefGoogle ScholarPubMed
Cassidy, F., Forest, K., Murry, E., et al. A factor analysis of the signs and symptoms of maniaArch Gen Psychiatr. 1998;55:2732.CrossRefGoogle ScholarPubMed
Dilsaver, S.C., Benazzi, F., Akiskal, H.S. Mixed states: the most common outpatient presentation of bipolar depressed adolescents? Psychopathology. 2005;38:268–72.CrossRefGoogle ScholarPubMed
Fibiger, H.C. Psychiatry, the pharmaceutical industry and the road to better therapeutics. Schizophr Bull. 2012;38:649–50.CrossRefGoogle ScholarPubMed
Frye, M.A., Ketter, T.A., Kimbrell, T.A., et al. A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders. J Clin Psychopharmacol. 2000;20:607–14.CrossRefGoogle ScholarPubMed
Geller, B., Zimerman, B., Williams, M., et al. Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder. Am J Psychiatry. 2001;158:125–7.CrossRefGoogle ScholarPubMed
Gould, T.D., Chen, G., Manji, H.K. In vivo evidence in the brain for lithium inhibition of glycogen synthesase kinase-3. Neropsychopharmacology. 2004;29:32–8.Google Scholar
Grunze, H., Erfuth, A., Marcuse, A., et al. Tiagabine appears not to be efficacious in acute mania. J Clin Psychiatr. 1999;60:759–62.CrossRefGoogle Scholar
Hollander, E., Lopez, A.A., Bienstock, C.A., et al. A preliminary double-blind, placebo controlled trial of divalproex sodium in borderline personality disorder. J Clin Psychiatr. 2001:199–2003.CrossRefGoogle ScholarPubMed
Hollander, E., Tracy, K.A., Swann, A.C., et al. Divalproex in the treatment of impulsive aggressive: efficacy in cluster B personality disorders. Neuropsychopharmacology. 2003;28:1186–97.CrossRefGoogle ScholarPubMed
Kendler, K.S. A gene for…the nature of gene action in psychiatric disorders. Am J Psychiatr. 2005;162: 1243–595.CrossRefGoogle Scholar
Kessler, R.C., Chiu, W.T., Demler, O., et al. Prevalence, severity, and comorbidity of 12-month DSM·IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatr. 2005;62:590–2.Google ScholarPubMed
Kupfer, D.J., Frank, E., Grochocinski, V.J., et al. Demographic and clinical characteristics of individuals in a bipolar disorder case registry. J Clin Psychiatry. 2002;63:120–5.CrossRefGoogle Scholar
Leon, A.C. Evolution of psychopharmacology trial design and analysis: six decades in the making. J Clin Psychiatry. 2011;72:331–40.CrossRefGoogle Scholar
Mitchell, P.B., Hadzi-Pavlovic, D., Evoniuk, G., et al. Factor analytic study in bipolar depression, and response to lamotrigine. CNS Spectrum. 2013;18:214–24.CrossRefGoogle ScholarPubMed
Pande, A.C., Crockatt, J.G., Janney, C.A., et al. Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group. Bipolar Disord. 2000;2:249–55.CrossRefGoogle ScholarPubMed
Paul, S.M., Mytelka, D.S., Dunwiddie, C.T., et al. How to improve R&D productivity: the pharmaceutical industry’s grand challenge. Nature reviews. Drug Discov. 2010;9:203–14.CrossRefGoogle Scholar
Stahl, S.M. Dopamine system stabilizers, aripiprazole and the next generation of antipsychotics: illustrating their mechanism of action. J Clin Psychiatr. 2001;62:923–4.Google ScholarPubMed
Swann, A.C., Janicak, P.L., Calabrese, J. R., et al. Structure of mania, depressive, irritable, and psvchotic clusters with distinct course of illness in randomized clinical trial participants. J Affect Disord. 2001;67:123–32.CrossRefGoogle ScholarPubMed
Swann, A.C., Bowden, C. L., Calabrese, J.R., et al. Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of mania. Neuropsychopharmacology. 2002;26:530–6.CrossRefGoogle ScholarPubMed
Tohen, M., Goldberg, J. F., Gonzalez-Pinto Arrillaga, A.M.., et al. A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania. Arch Gen Psychiatr. 2003;60(12):1218–26.CrossRefGoogle ScholarPubMed
Tohen, M., Chengappa, K. N., Suppes, T., et al. Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser vs mood stabiliser alone. Br J Psychiatry. 2004a; 18–1:337-3-15.Google Scholar
Tohen, M., Vieta, E., Calabrese, J.R., et al. Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch Gen Psychiatr. 2004b;61:1079–88.Google Scholar
Wang, P.W., Yang, Y., Chandler, R.A., et al. Adjunctive zonisamide for weight loss in euthymic bipolar disorder patients: a pilot study. J Psychiatr Res. 2008;42: 451–7.CrossRefGoogle ScholarPubMed
Williams, J. B., Gibbon, M., First, M.B., et al. The structured clinical interview for DSM-111-R (SCID) II. multisite test-retest reliability·. Arch Gen Psychiatry. 1992;9(8):630–6.Google Scholar

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