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  1. Home
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  3. Behavioral Genetics of the Mouse
  • Cited by 5
  • Volume 2: Genetic Mouse Models of Neurobehavioral Disorders
  • Edited by Susanna Pietropaolo, Centre National de la Recherche Scientifique (CNRS), Paris, Frans Sluyter, University of Portsmouth, Wim E. Crusio, Centre National de la Recherche Scientifique (CNRS), Paris
Publisher:
Cambridge University Press
Online publication date:
October 2014
Print publication year:
2014
Online ISBN:
9781107360556
DOI:
https://doi.org/10.1017/CBO9781107360556
Subjects:
Animal Behaviour, Genetics, Life Sciences, Neurology and Clinical Neuroscience, Medicine
Series:
Cambridge Handbooks in Behavioral Genetics
Information

Book description

The second volume of Behavioral Genetics of the Mouse provides a comprehensive overview of the major genetically modified mouse lines used to model human neurobehavioral disorders: from disorders of perception, of autonomous and motor functions to social and cognitive syndromes, drug abuse and dependence as well as neurodegenerative pathologies. Mouse models obtained with different types of genetic manipulations (i.e. transgenic, knockout/in mice) are described in their pathological phenotypes, with a special emphasis on behavioral abnormalities. The major results obtained with many of the existing models are discussed in depth highlighting their strengths and limitations. A lasting reference, the thorough reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

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