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Chapter 1 - Pathophysiology of Epilepsy

Published online by Cambridge University Press:  11 October 2019

Vibhangini S. Wasade
Henry Ford Medical Group HFHS, Michigan
Marianna V. Spanaki
Wayne State University, Michigan
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A seizure is a situational clinical event that may be instigated by any number of extrinsic or intrinsic precipitating factors and that results in an excessive, hypersynchronous discharge of a cortical neuronoglial population and manifests in the brain in either a localized or widespread manner. This abnormal activity takes over the normal functioning of one or more brain networks to result in seizures that characterize over 40 recognized epileptic syndromes.1

Understanding Epilepsy
A Study Guide for the Boards
, pp. 1 - 18
Publisher: Cambridge University Press
Print publication year: 2019

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