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Chapter 10 - Principles of Head Injury Intensive Care Management

Published online by Cambridge University Press:  28 April 2020

Peter C. Whitfield
Derriford Hospital, Plymouth
Jessie Welbourne
University Hospitals, Plymouth
Elfyn Thomas
Derriford Hospital, Plymouth
Fiona Summers
Aberdeen Royal Infirmary
Maggie Whyte
Aberdeen Royal Infirmary
Peter J. Hutchinson
Addenbrooke’s Hospital, Cambridge
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Traumatic brain injury (TBI) encompasses a continuum of primary and secondary injurious processes. Primary injury describes the irreversible structural damage sustained at the time of impact. It initiates a host response which results in a cascade of biochemical, cellular and molecular events that lead to further (secondary) brain injury.1 Advances in neuromonitoring and neuroimaging techniques, in association with improved understanding of the pathophysiology of TBI, have led to the introduction of more effective critical care treatment strategies aimed at preventing or minimising secondary injury that have translated into improved outcomes for patients.

Traumatic Brain Injury
A Multidisciplinary Approach
, pp. 97 - 109
Publisher: Cambridge University Press
Print publication year: 2020

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