In 2011, a 10-year-old boy came to the ER for recurrent epistaxis. His medical history showed frequent episodes of headache and epistaxis; otherwise, he had a regular life, good school profile and practiced regular physical activity. His father, affected by cerebral arteriovenous malformation (AVM), has been diagnosed with hereditary hemorrhagic telangiectasia (HHT – also called Osler–Weber–Rendu syndrome). On admission, he was asymptomatic and his blood work was within normal limits.