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Chapter 5 - Sperm DNA

Published online by Cambridge University Press:  16 February 2022

David Mortimer
Oozoa Biomedical Inc., Vancouver
Lars Björndahl
Karolinska Institutet, Stockholm
Christopher L. R. Barratt
University of Dundee
José Antonio Castilla
HU Virgen de las Nieves, Granada
Roelof Menkveld
Stellenbosch University, South Africa
Ulrik Kvist
Karolinska Institutet, Stockholm
Juan G. Alvarez
Centro ANDROGEN, La Coruña
Trine B. Haugen
Oslo Metropolitan University
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Discusses the origins and detection of sperm DNA fragmentation, including cliniCal indications for such testing. Provides methods for a range of common techniques for assessimg sperm DNA fragmentation that are structured as standard operating procedures (SOPs) for easy use at the bench, inclding the TUNEL assay, Comet assay, and the sperm chromatin dispersion test (Halosperm test).

Publisher: Cambridge University Press
Print publication year: 2022

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