Skip to main content Accessibility help
×
Home
Hostname: page-component-544b6db54f-bkjnw Total loading time: 1.013 Render date: 2021-10-21T00:03:45.769Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Chapter 24 - Placental bed disorders in the genesis of the great obstetrical syndromes

from Section 8: - Translation to obstetrics

Published online by Cambridge University Press:  06 July 2010

Robert Pijnenborg
Affiliation:
University Hospital Gasthuisberg, Leuven
Ivo Brosens
Affiliation:
Leuven Institute for Fertility and Embryology
Roberto Romero
Affiliation:
National Institute of Child Health and Human Development, Detroit
Get access

Summary

This chapter reviews evidence that failure of physiological transformation of the spiral arteries is observed in preterm labor, preterm premature rupture of membranes (PROM), and abruptio placentae. The first study to examine the morphology of the placental bed in idiopathic, sporadic, and recurrent spontaneous abortion was reported by T. Y. Khong and his colleagues. Preterm PROM accounts for one-third of all preterm births, and is often a leading cause of spontaneous preterm labor. Pregnancy requires vasculogenesis and angiogenesis in the fetal compartment and angiogenesis in the maternal compartment. The current taxonomy of disease in obstetrics is based on the clinical presentation of the mother and/or fetus, and not on the mechanism of disease responsible for the clinical manifestations. Evolutionary pressures derived from the potential conflictual relationship between the fetus and mother is likely to play a role.
Type
Chapter
Information
Placental Bed Disorders
Basic Science and its Translation to Obstetrics
, pp. 271 - 289
Publisher: Cambridge University Press
Print publication year: 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)
7
Cited by

Send book to Kindle

To send this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Send book to Dropbox

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox.

Available formats
×

Send book to Google Drive

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive.

Available formats
×