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Section X - Pediatric and Adolescent Problems

Published online by Cambridge University Press:  20 February 2019

David Chelmow
Virginia Commonwealth University
Nicole W. Karjane
Virginia Commonwealth University
Hope A. Ricciotti
Harvard Medical School
Amy E. Young
University of Texas, Austin
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Office Gynecology
A Case-Based Approach
, pp. 196 - 225
Publisher: Cambridge University Press
Print publication year: 2019

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Committee on Adolescent Health Care. Committee Opinion No. 686: Breast and Labial Surgery in Adolescents. Obstet Gynecol 2017 January;129(1): e17e19.CrossRef
Bercaw-Pratt, JL, Santos, XM, Sanchez, J et al. The incidence, attitudes and practices of the removal of pubic hair as a body modification. J Pediatr Adolesc Gynecol 2012 February;25(1):1214.CrossRefGoogle ScholarPubMed
Lloyd, J, Crouch, NS, Minto, CL et al. Female genital appearance: “normality” unfolds. BJOG Int J Obstet Gynaecol 2005;112:643646.CrossRefGoogle ScholarPubMed
Clerico, C, Lari, A, Mojallal, A, et al. Anatomy and aesthetics of the labia minora: the ideal vulva? Aesthetic Plast Surg 2017 March 10. doi: 10.1007/s00266-017–0831-1. Epub ahead of print.CrossRef
NASPAG Handouts for Patients. Labial Hypertrophy., accessed 4/2017.
Brohede, S, Wingren, G, Wijma, B et al. Validation of the body dysmorphic disorder questionnaire in a community sample of Swedish women. Psychiatry Res 2013 December 15;210(2):647652.CrossRefGoogle Scholar
Runacres, SA, Wood, PL. Cosmetic labiaplasty in an adolescent population. J Pediatr Adolesc Gynecol 2016 June;29(3):218222.CrossRefGoogle Scholar
Reddy, J, Laufer, MR. Hypertrophic labia minora. J Pediatr Adolesc Gynecol 2010 February;23(1):36.CrossRefGoogle ScholarPubMed
Fauser, BC, Tarlatzis, RW, Rebar, RS et al. Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-sponsored 3rd PCOS consensus workshop group. Fertil Steril 2012;97:2838.e25.CrossRefGoogle ScholarPubMed
Carmina, E, Rosato, F, Janni, A, Rizzo, M, Longo, RA. Extensive clinical experience: relative prevalence of different androgen excess disorders in 950 women referred because of clinical hyperandrogenism. J Clin Endocrinol Metab 2006;91:26.CrossRefGoogle ScholarPubMed
Rosenfield, RL. Identifying children at risk of polycystic ovary syndrome. J Clin Endocrinol Metab 2007;92:787796.CrossRefGoogle ScholarPubMed
Franks, S. Polycystic ovary syndrome in adolescents. Int J Obes (Lond) 2008;32:10351041.CrossRefGoogle ScholarPubMed
Johnson, T, Kaplan, L, Ouyang, P, Rizza, R. National Institutes of Health Evidence-Based Methodology Workshop on Polycystic Ovary Syndrome (PCOS). NIH EbMW Report. Bethesda, National Institutes of Health 2012;1:114.Google Scholar
Witchel, SF, Oberfield, S, Rosenfield, RL et al. The diagnosis of polycystic ovary syndrome during adolescence. Horm Res Paediatr 2015;83:376389.CrossRefGoogle Scholar
American College of Obstetricians and Gynecologists. Polycystic ovary syndrome. ACOG practice bulletin no. 194. Obstet Gynecol 2018;131:e157–71.
Javed, A, Chelvakumar, G, Bonny, AE. Polycystic ovary syndrome in adolescents: a review of past yearevidence. Curr Opin Obstet Gynecol 2016;28:373380.CrossRefGoogle Scholar
Rosenfield, RL. The diagnosis of polycystic ovary syndrome in adolescents. Pediatrics 2015;136:11541165.CrossRefGoogle Scholar
Legro, RS, Arslanian, SA, Ehrmann, DA et al. Diagnosis and treatment of polycystic ovary syndrome: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2013;98:45654592.CrossRefGoogle Scholar
Ornstein, RM, Copperman, NM, Jacobson, MS. Effect of weight loss on menstrual function in adolescents with polycystic ovary syndrome. J Pediatr Adolesc Gynecol 2011;24:161165.CrossRefGoogle ScholarPubMed
Powell, J. Wonjnarowska, F. Childhood vulvar lichen sclerosus: an increasingly common problem. J Am Acad Dermatol 2001;44:803.CrossRefGoogle Scholar
Lagerstedt, M Karvinen, K. Joki-Errila, M. Childhood lichen sclerosus, a challenge for clinicians. Pediatr Dermatol 2013;30:444.CrossRefGoogle ScholarPubMed
Bercaw-Pratt, JL, Boardman, LA, Simms-Cendan, JS, North American Society for Pediatric and Adolescent Gynecology: Clinical recommendation: pediatric lichen sclerosus. J Pediatr Adolesc Gynecol 2014 April;27:111116.CrossRefGoogle ScholarPubMed
Dendrinos, ML, Quint, EH. Lichen sclerosus in children and adolescents. Curr Opin Obstet Gynecol 2013 October;25:370374.CrossRefGoogle ScholarPubMed
Casey, GA, Cooper, SM, Powell, JJ. Treatment of vulvar lichen sclerosus with topical corticosteroids in children: a study of 72 children. Clin Exp Dermatol 2015;40:289.CrossRefGoogle ScholarPubMed
Chi, CC, Kirtschig, G, Baldo, M et al. Topical interventions for genital lichen sclerosus. Cochrane Database Syst Rev 2001; (12) CD008240.Google Scholar
Dinh, H, Purcell, SM, Chung, C, Zaenglein, AL. Pediatric lichen sclerosus: a review of the literature and management recommendations. J Clin Aesthet Dermatol 2016;9(9):4954.Google ScholarPubMed
Smith, SD, Fischer, G. Childhood onset of vulvar lichen sclerosus does not resolve at puberty: a prospective case series. Pediatr Dermatol 2009;26:725.CrossRefGoogle Scholar
Tong, LX, Sun, GS, Teng, JM. Pediatric lichen sclerosus: A review of the epidemiology and treatment options. Pediatr Dermatol 2015 September–October;32(5):593599. doi: 10.1111/pde.12615. Epub May 4, 2015.CrossRefGoogle ScholarPubMed
Sanfilippo, J, Lara-Torre, E, Edmonds, K, Templeman, C. Clinical Pediatric and Adolescent Gynecology. New York, NY: Informa Health Care;2009.Google Scholar
Zuckerman, A, Romano, M. Clinical recommendation: vulvovaginitis. J Pediatr Adolesc Gynecol 2016;29:673679.CrossRefGoogle ScholarPubMed
Stricker, T, Navratil, F, Sennhauser, FH. Vulvovaginitis in prepubertal girls. Arch Dis Child 2003;88:324326.CrossRefGoogle ScholarPubMed
Cemek, F, Odabas, D, Senel, U, Kocaman, AT. Personal hygiene and vulvovaginitis in prepubertal children. J Pediatr Adolesc Gynecol 2016 June;29(3) 223227.CrossRefGoogle ScholarPubMed
Randelovic, G, Mladenovic, V, Ristic, L et al. Microbiological apsects of vulvovaginitis in prepubertal girls. J Formos Med Assoc 2012;111:392396.Google Scholar
Farhi, D, Wendling, J, Molinari, E et al. Non-sexually related acute genital ulcers in 13 pubertal girls: a clinical and microbiological study. Arch Dermatol 2009;145(1):3845.CrossRefGoogle ScholarPubMed
Huppert, JS. Lipschutz ulcers: evaluation and management of acute genital ulcers in women. Dermatol Ther 2010;23(5):533540.CrossRefGoogle ScholarPubMed
Huppert, JS, Gerber, MA, Deitch, HR et al. Vulvar ulcers in young females: a manifestation of aphthosis. J Pediatr Adolesc Gynecol 2006;19(3):195204.CrossRefGoogle ScholarPubMed
Vieira-Baptista, P, Lima-Silva, J, Beires, J, Martinez-de-Oliveira, J. Lipschutz ulcers: should we rethink this? An analysis of 33 cases. Eur J Obstet Gynecol Reprod Biol 2016;198:149152.CrossRefGoogle ScholarPubMed
Prevention CfDCa. Sexually Transmitted Diseases Treatment Guidelines. MMWR. 2010;59(RR-12):18–26.
Gomes, CM, Giraldo, PC, Gomes Fde, A et al. Genital ulcers in women: clinical, microbiologic and histopathologic characteristics. Braz J Infect Dis 2007;11(2):254260.CrossRefGoogle ScholarPubMed
Berkowitz, CD, Elvik, SL, McCann, J et al. Septate hymen: variations and pitfalls in diagnosis. Adolesc Pediatr Gynecol 1991;4:194197.CrossRefGoogle Scholar
Shulman, LP, Elias, S. Developmental abnormalities of the female reproductive tract: pathogenesis and nosology. Adolesc Pediatr Gynecol 1988;1:230238.CrossRefGoogle Scholar
Emans, SJ. Office evaluation of the child and adolescent. In: Emans, SJ, Laufer, MR, editors. Emans, Laufer, Goldstein’s Pediatric and Adolescent Gynecology, 6th Edition. Philadelphia: Lippincott Williams & Wilkins; 2012. pp. 120.Google Scholar
Segal, TR, Fried, WB, Krim, EY, Parikh, D, Rosenfeld, DL. Treatment of microperforate hymen with serial dilation: a novel approach. J Pediatr Adolesc Gynecol 2014; 28(2): e21e22.CrossRefGoogle ScholarPubMed
Gebhart, JP, Breech, LL, Hurst, BS, Rock, JA. Congenital vaginal abnormalities. In: Baggish, MS, Karram, MM, editors. Atlas of Pelvic Anatomy and Gynecologic Surgery, 4th Edition. Philadelphia: Elsevier; 2016. pp. 779798.Google Scholar
Kaplowitz, P, Bloch, C, The SECTION ON ENDOCRINOLOGY. Evaluation and referral of children with signs of early puberty. Pediatrics 2016;137(1):e20153732.CrossRefGoogle ScholarPubMed
Herman-Giddens, ME, Slora, EJ, Wasserman, RC et al. Secondary sexual characteristics and menses in young girls seen in office practice: a study from the Pediatric Research in Office Settings network. Pediatrics 1997;99(4):505512.CrossRefGoogle ScholarPubMed
Wu, T, Mendola, P, Buck, GM. Ethnic differences in the presence of secondary sex characteristics and menarche among US girls: the Third National Health and Nutrition Examination Survey, 1988–1994.Pediatrics 2002;110(4):752757.CrossRefGoogle ScholarPubMed
Biro, FM, Galvez, MP, Greenspan, LC et al. Pubertal assessment method and baseline characteristics in a mixed longitudinal study of girls. Pediatrics 2010;126(3).CrossRefGoogle Scholar
Rosenfield, RL, Lipton, RB, Drum, ML. Thelarche, pubarche, and menarche attainment in children with normal and elevated body mass index. Pediatrics 2009;123(1):8488.CrossRefGoogle ScholarPubMed
Berberoglu, M. Precocious puberty and normal variant puberty: definition, etiology, diagnosis and current management. J Clin Res Pediatr Endocrinol 2009 June; 1(4):164174. Published online December 8, 2010.CrossRefGoogle ScholarPubMed
Vallerie, AM, Breech, LL. Update in Müllerian anomalies: diagnosis, management, and outcomes. Curr Opin Obstet Gynecol 2010;22:381387.CrossRefGoogle Scholar
Atencio, FP, Yabes-Almirante, C. Abnormalities in Development. Atlas of Pediatric and Adolescent Gynecology. JP Medical Ltd. 2012;3249.
Creighton, SM. Common congenital anomalies of the female genital tract. Reviews in Gynaecological Practice 2005;5:221226.CrossRefGoogle Scholar
Laufer, MR, Barbieri, RL, Falk, SJ. Diagnosis and management of congenital anomalies of the vagina. UpToDate® 2015; Literature current through April, 2017.
Wheeless, CR, Roenneburg, ML. Atlas of Pelvic Surgery. Lippincott Williams & Wilkins. 1997.Google Scholar
Lardenoije, C, Aardenburg, R, Mertens, H. Imperforate hymen: a cause of abdominal pain in female adolescents. BMJ Case Rep 2009.
Sucato, GS, Murray, PJ. Pediatric and Adolescent Gynecology. Atlas of Pediatric Physical Diagnosis. Saunders, an imprint of Elsevier Inc. 2012;693730.
Dietrich, JE, Millar, DM, Quint, EH. Obstructive reproductive tract anomalies. J Pediatr Adolesc Gynecol December 2014;27(6):396402.CrossRefGoogle ScholarPubMed
American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5). 5th ed. Arlington, VA.: American Psychiatric Publishing; 2013.
Smink, F, van Hoeken, D, Hoek, H. Epidemiology of eating disorders: incidence, prevalence and mortality rates. Curr Psychiatry Rep 2012;14(4):406414.CrossRefGoogle ScholarPubMed
Andersen, A, Ryan, G. Eating disorders in the obstetric and gynecologic patient population. Obstet Gynecol 2009;114(6):13531367.CrossRefGoogle ScholarPubMed
Boisseau, C. Identification and management of eating disorders in gynecology: menstrual health as an underutilized screening tool. Am J Obstet Gynecol 2016;215(5):572578.CrossRefGoogle ScholarPubMed
Linna, M, Raevuori, A, Haukka, J et al. Pregnancy, obstetric, and perinatal health outcomes in eating disorders. Am J Obstet Gynecol 2014;211(4):392.e1392.e8.CrossRefGoogle ScholarPubMed
Morgan, JF, Reid, F, Lacey, JH. The SCOFF questionnaire: assessment of a new screening tool for eating disorders. BMJ 1999;319:14671468.CrossRefGoogle ScholarPubMed
Witkop, C, Warren, M. Understanding the spectrum of the female athlete triad. Obstet Gynecol. 2010;116(6):14441448.CrossRefGoogle ScholarPubMed
Sieke, E, Rome, E. Eating disorders in children and adolescents: what does the gynecologist need to know? Curr Opin Obstet Gynecol 2016;28(5):381392.CrossRefGoogle ScholarPubMed
Arcelus, J. Mortality rates in patients with anorexia nervosa and other eating disorders. Arch Gen Psychiatry 2011;68(7):724.CrossRefGoogle ScholarPubMed

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