Book contents
- Mood Disorders
- Mood Disorders
- Copyright page
- Contents
- Contributors
- Preface
- Section 1 General
- Section 2 Anatomical Studies
- Section 3 Functional and Neurochemical Brain Studies
- Section 4 Novel Approaches in Brain Imaging
- Section 5 Therapeutic Applications of Neuroimaging in Mood Disorders
- Chapter 17 Effects of Lithium on Brain Structure in Bipolar Disorder
- Chapter 18 Molecular Imaging of Dopamine and Antipsychotics in Bipolar Disorder
- Chapter 19 Brain Imaging and the Mechanisms of Antidepressant Action
- Chapter 20 Neuroimaging Studies of Effects of Psychotherapy in Depression
- Index
- Plate Section (PDF Only)
- References
Chapter 19 - Brain Imaging and the Mechanisms of Antidepressant Action
from Section 5 - Therapeutic Applications of Neuroimaging in Mood Disorders
Published online by Cambridge University Press: 12 January 2021
- Mood Disorders
- Mood Disorders
- Copyright page
- Contents
- Contributors
- Preface
- Section 1 General
- Section 2 Anatomical Studies
- Section 3 Functional and Neurochemical Brain Studies
- Section 4 Novel Approaches in Brain Imaging
- Section 5 Therapeutic Applications of Neuroimaging in Mood Disorders
- Chapter 17 Effects of Lithium on Brain Structure in Bipolar Disorder
- Chapter 18 Molecular Imaging of Dopamine and Antipsychotics in Bipolar Disorder
- Chapter 19 Brain Imaging and the Mechanisms of Antidepressant Action
- Chapter 20 Neuroimaging Studies of Effects of Psychotherapy in Depression
- Index
- Plate Section (PDF Only)
- References
Summary
The history of pharmacological treatments for depression began in the 1950s, with the serendipitous discovery of the antidepressant potential of drugs like the tricyclic antidepressant, imipramine. Since then, many new, safer, and better tolerated, antidepressant drugs have appeared on the market (1), and now depression can be treated widely in primary care. However, finding a treatment effective for an individual patient is not a trivial task, with only around 30% of patients responding to their first antidepressant (AD) medication, most requiring multiple changes, and about one-third not responding at all (2).
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- Information
- Mood DisordersBrain Imaging and Therapeutic Implications, pp. 248 - 260Publisher: Cambridge University PressPrint publication year: 2021