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Chapter 7 - Piezo: The Add-On to Standardize ICSI Procedure

Published online by Cambridge University Press:  02 December 2021

Gianpiero D. Palermo
Cornell Institute of Reproductive Medicine, New York
Zsolt Peter Nagy
Reproductive Biology Associates, Atlanta, GA
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The primary benefit of piezo-ICSI lies in the standardization and simplification of the ICSI procedure, resulting in a considerably shorter learning curve compared to the conventional technique. The success of the ICSI procedure becomes independent of the embryologist, providing the clinic with more robust and predictable laboratory output. Piezo might be the first step towards automatizing the ICSI procedure. Piezo-ICSI also has promise to be the method of choice in cases of more sensitive/fragile oocytes and in older age groups. In patients older than 35 years evidence seems to show further benefits after ICSI in significantly decreased oocyte degeneration rate and increased blastocyst rate. Clinical experiences highlight the spread of the technique in human IVF; however, the operating liquid currently used in the injecting microcapillary is an obstacle for human registration.

Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction
With Other Advanced Micromanipulation Techniques to Edit the Genetic and Cytoplasmic Content of the Oocyte
, pp. 66 - 79
Publisher: Cambridge University Press
Print publication year: 2021

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