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7 - Obsessive-Compulsive and Related Disorders

Published online by Cambridge University Press:  22 July 2021

By
Ryan J. Jacoby ,
Amanda W. Baker ,
Michael A. Jenike ,
Scott L. Rauch  and
Sabine Wilhelm
Edited by
Audrey Walker ,
Steven Schlozman  and
Jonathan Alpert
Audrey Walker
Affiliation:
Albert Einstein College of Medicine, New York
Steven Schlozman
Affiliation:
Harvard Medical School
Jonathan Alpert
Affiliation:
Albert Einstein College of Medicine, New York
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Summary

This chapter presents an overview of the nature, assessment, and treatment of obsessive-compulsive and related disorders (OCRD), including obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), hoarding disorder (HD), hair-pulling disorder (HPD), and skin-picking disorder (SPD). Specifically, we review the DSM-V diagnostic criteria, epidemiology and impact, clinical features and course, and etiological insights for each of these disorders in turn. Next, we discuss key points to consider when making a differential diagnosis with disorders outside the OCRD category. From there, we turn to a discussion of the assessment and treatment of these disorders using pharmacological, cognitive-behavioral, and neuromodulation interventions. Future directions in the research on OCRDs then follows.

Type
Chapter
Information
Introduction to Psychiatry
Preclinical Foundations and Clinical Essentials
 , pp. 146 - 165
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Selected Readings

Abramowitz, J. S., and Jacoby, R. J. (2015). Obsessive-Compulsive and Related Disorders: A Critical Review of the New Diagnostic Class. Annual Review of Clinical Psychology, 11, 165–186.CrossRefGoogle ScholarPubMed
Abramowitz, J. S., Schwartz, S. A., and Whiteside, S. P. (2002). A Contemporary Conceptual Model of Hypochondriasis. Mayo Clinic Proceedings, 77(12), 1323–1330.CrossRefGoogle ScholarPubMed
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Arlington, VA: American Psychiatric Publishing.Google Scholar
Bjornsson, A. S., Didie, E. R., and Phillips, K. A. (2010). Body Dysmorphic Disorder. Dialogues in Clinical Neuroscience, 12(2), 221–232.CrossRefGoogle ScholarPubMed
Blom, R. M., Figee, M., Vulink, N., and Denys, D. (2011). Update on Repetitive Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Different Targets. Current Psychiatry Reports, 13(4), 289–294.CrossRefGoogle ScholarPubMed
Buhlmann, U., Glaesmer, H., Mewes, R., Fama, J. M., Wilhelm, S., Brähler, E., and Rief, W. (2010). Updates on the Prevalence of Body Dysmorphic Disorder: A Population-Based Survey. Psychiatry Research, 178(1), 171–175.CrossRefGoogle ScholarPubMed
Casale, A. D., Sorice, S., Padovano, A., Simmaco, M., Ferracuti, S., Lamis, D. A., … Pompili, M. (2018). Psychopharmacological Treatment of Obsessive-Compulsive Disorder (OCD). Current Neuropharmacology. https://doi.org/10.2174/1570159X16666180813155017.CrossRefGoogle Scholar
Craske, M. G., Kircanski, K., Zelikowsky, M., Mystkowski, J., Chowdhury, N., and Baker, A. (2008). Optimizing Inhibitory Learning during Exposure Therapy. Behaviour Research and Therapy, 46(1), 5–27.CrossRefGoogle ScholarPubMed
Dougherty, D. D., Brennan, B. P., Stewart, S. E., Wilhelm, S., Widge, A. S., and Rauch, S. L. (2018). Neuroscientifically Informed Formulation and Treatment Planning for Patients with Obsessive-Compulsive Disorder: A Review. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2018.0930.CrossRefGoogle Scholar
Feusner, J. D., Phillips, K. A., and Stein, D. J. (2010). Olfactory Reference Syndrome: Issues for DSM-V. Depression and Anxiety, 27(6), 592–599.CrossRefGoogle ScholarPubMed
Fineberg, N. A., Kaur, S., Kolli, S., Mpavaenda, D., and Reghunandanan, S. (2015). Obsessive-Compulsive Personality Disorder. In Phillips, K. A. and Stein, D. J. (eds.), Handbook on Obsessive-Compulsive and Related Disorders (pp. 247–272). Arlington, VA: American Psychiatric Publishing.Google Scholar
First, M., Williams, J., Karg, R., and Spitzer, R. (2015). Structured Clinical Interview for DSM-V. Arlington, VA: American Psychiatric Association.Google Scholar
Foa, E. B., Huppert, J. D., Leiberg, S., Langner, R., Kichic, R., Hajcak, G., and Salkovskis, P. M. (2002). The Obsessive-Compulsive Inventory: Development and Validation of a Short Version. Psychological Assessment, 14(4), 485–496.CrossRefGoogle ScholarPubMed
Frost, R. O., Steketee, G., and Grisham, J. (2004). Measurement of Compulsive Hoarding: Saving Inventory-Revised. Behaviour Research and Therapy, 42(10), 1163–1182.CrossRefGoogle ScholarPubMed
Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Delgado, P., Heninger, G. R., and Charney, D. S. (1989). The Yale-Brown Obsessive-Compulsive Scale: II. Validity. Archives of General Psychiatry, 46(11), 1012–1016.CrossRefGoogle ScholarPubMed
Grant, J. E., and Chamberlain, S. R. (2016). Trichotillomania. American Journal of Psychiatry, 173(9), 868–874.CrossRefGoogle ScholarPubMed
Grant, J. E., Odlaug, B. L., Chamberlain, S. R., Keuthen, N. J., Lochner, C., and Stein, D. J. (2012). Skin-Picking Disorder. American Journal of Psychiatry, 169(11), 1143–1149.CrossRefGoogle ScholarPubMed
Greenberg, B. D., Gabriels, L. A., Malone, D. A., Rezai, A. R., Friehs, G. M., Okun, M. S., … Nuttin, B. J. (2010). Deep Brain Stimulation of the Ventral Internal Capsule/Ventral Striatum for Obsessive-Compulsive Disorder: Worldwide Experience. Molecular Psychiatry, 15(1), 64–79.CrossRefGoogle ScholarPubMed
Greenberg, J. L., Falkenstein, M., Reuman, L., Fama, J., Marques, L., and Wilhelm, S. (2013). The Phenomenology of Self-Reported Body Dysmorphic Disorder by Proxy. Body Image, 10(2), 243–246.CrossRefGoogle ScholarPubMed
Jacoby, R. J., and Abramowitz, J. S. (2016). Inhibitory Learning Approaches to Exposure Therapy: A Critical Review and Translation to Obsessive-Compulsive Disorder. Clinical Psychology Review, 49, 28–40.CrossRefGoogle ScholarPubMed
Keuthen, N. J., O’Sullivan, R. L., Ricciardi, J. N., Shera, D., Savage, C. R., Borgmann, A. S., … Baer, L. (1995). The Massachusetts General Hospital (MGH) Hairpulling Scale: 1. Development and Factor Analyses. Psychotherapy and Psychosomatics, 64(3–4), 141–145.CrossRefGoogle ScholarPubMed
Kozak, M. J., and Foa, E. B. (1994). Obsessions, Overvalued Ideas, and Delusions in Obsessive-Compulsive Disorder. Behaviour Research and Therapy, 32(3), 343–353.CrossRefGoogle ScholarPubMed
Kyrios, M., Ahern, C., Fassnacht, D. B., Nedeljkovic, M., Moulding, R., and Meyer, D. (2018). Therapist-Assisted Internet-Based Cognitive Behavioral Therapy versus Progressive Relaxation in Obsessive-Compulsive Disorder: Randomized Controlled Trial. Journal of Medical Internet Research, 20 (8), e242.CrossRefGoogle ScholarPubMed
Mataix-Cols, D., Frost, R. O., Pertusa, A., Clark, L. A., Saxena, S., Leckman, J. F., … Wilhelm, S. (2010). Hoarding Disorder: A New Diagnosis for DSM-V? Depression and Anxiety, 27 (6), 556–572.CrossRefGoogle ScholarPubMed
Milad, M. R., Furtak, S. C., Greenberg, J. L., Keshaviah, A., Im, J. J., Falkenstein, M. J., … Wilhelm, S. (2013). Deficits in Conditioned Fear Extinction in Obsessive-Compulsive Disorder and Neurobiological Changes in the Fear Circuit. JAMA Psychiatry, 70 (6), 608–618.CrossRefGoogle ScholarPubMed
Olatunji, B. O., Davis, M. L., Powers, M. B., and Smits, J. A. J. (2013). Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder: A Meta-Analysis of Treatment Outcome and Moderators. Journal of Psychiatric Research, 47(1), 33–41.CrossRefGoogle ScholarPubMed
Patel, S. R., Wheaton, M. G., Andersson, E., Rück, C., Schmidt, A. B., La Lima, C. N., … Simpson, H. B. (2018). Acceptability, Feasibility, and Effectiveness of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in New York. Behavior Therapy, 49(4), 631–641.CrossRefGoogle ScholarPubMed
Phillips, K. A., and Hollander, E. (2008). Treating Body Dysmorphic Disorder with Medication: Evidence, Misconceptions, and a Suggested Approach. Body Image, 5 (1), 13–27.CrossRefGoogle Scholar
Phillips, K. A., Hollander, E., Rasmussen, S. A., Aronowitz, B. R., DeCaria, C., and Goodman, W. K. (1997). A Severity Rating Scale for Body Dysmorphic Disorder: Development, Reliability, and Validity of a Modified Version of the Yale-Brown Obsessive-Compulsive Scale. Psychopharmacology Bulletin, 33(1), 17–22.Google ScholarPubMed
Phillips, K. A., Pinto, A., Hart, A. S., Coles, M. E., Eisen, J. L., Menard, W., and Rasmussen, S. A. (2012). A Comparison of Insight in Body Dysmorphic Disorder and Obsessive-Compulsive Disorder. Journal of Psychiatric Research, 46(10), 1293–1299.CrossRefGoogle ScholarPubMed
Phillips, K. A., Stein, D. J., Rauch, S. L., Hollander, E., Fallon, B. A., Barsky, A., … Leckman, J. (2010). Should an Obsessive-Compulsive Spectrum Grouping of Disorders Be Included in DSM-V? Depression and Anxiety, 27(6), 528–555.CrossRefGoogle ScholarPubMed
Snorrason, I., Belleau, E. L., and Woods, D. W. (2012). How Related Are Hair-Pulling Disorder (Trichotillomania) and Skin-Picking Disorder? A Review of Evidence for Comorbidity, Similarities and Shared Etiology. Clinical Psychology Review, 32(7), 618–629.CrossRefGoogle ScholarPubMed
Snorrason, I., Ólafsson, R. P., Flessner, C. A., Keuthen, N. J., Franklin, M. E., and Woods, D. W. (2012). The Skin Picking Scale-Revised: Factor Structure and Psychometric Properties. Journal of Obsessive-Compulsive and Related Disorders, 1(2), 133–137.CrossRefGoogle Scholar
Steketee, G., and Frost, R. O. (2014). Phenomenology of Hoarding. In Frost, R. O. and Steketee, G (eds.), The Oxford Handbook of Hoarding and Acquiring. (pp. 19–32). New York: Oxford University Press.Google Scholar
Steketee, G., Siev, J., Yovel, I., Lit, K., and Wilhelm, S. (2018). Predictors and Moderators of Cognitive and Behavioral Therapy Outcomes for OCD: A Patient-Level Mega-Analysis of Eight Sites. Behavior Therapy. https://doi.org/10.1016/j.beth.2018.04.004.CrossRefGoogle Scholar
Stewart, S. E., Yu, D., Scharf, J. M., Neale, B. M., Fagerness, J. A., Mathews, C. A., … Pauls, D. L. (2013). Genome-Wide Association Study of Obsessive-Compulsive Disorder. Molecular Psychiatry, 18(7), 788–798.CrossRefGoogle ScholarPubMed
Wilhelm, S., Greenberg, J. L., Rosenfield, E., Kasarskis, I., and Blashill, A. J. (2016). The Body Dysmorphic Disorder Symptom Scale: Development and Preliminary Validation of a Self-Report Scale of Symptom Specific Dysfunction. Body Image, 17, 82–87.CrossRefGoogle ScholarPubMed
Wilhelm, S., Phillips, K. A., Didie, E., Buhlmann, U., Greenberg, J. L., Fama, J. M., … Steketee, G. (2014). Modular Cognitive-Behavioral Therapy for Body Dysmorphic Disorder: A Randomized Controlled Trial. Behavior Therapy, 45(3), 314–327.CrossRefGoogle ScholarPubMed
Wilhelm, S., and Steketee, G. S. (2006). Cognitive Therapy for Obsessive-Compulsive Disorder: A Guide for Professionals. Oakland: New Harbinger.Google Scholar
Williams, M., and Viscusi, J. A. (2016). Hoarding Disorder and a Systematic Review of Treatment with Cognitive Behavioral Therapy. Cognitive Behaviour Therapy, 45(2), 93–110.CrossRefGoogle Scholar
Wu, M. S., Rudy, B. M., and Storch, E. A. (2014). Obsessions, Compulsions, and Repetitive Behavior: Autism and/or OCD. In Davis, T. E. I., White, S. W., and Ollendick, T. H. (eds.), Handbook of Autism and Anxiety (pp. 107–120). Cham, Switzerland: Springer.CrossRefGoogle Scholar

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