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Part II - Recent progress in cell mechanobiology

Published online by Cambridge University Press:  05 November 2015

Yu Sun
Affiliation:
University of Toronto
Deok-Ho Kim
Affiliation:
University of Washington
Craig A. Simmons
Affiliation:
University of Toronto
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Summary

Tumor angiogenesis is a key regulator of tumor growth and metastasis. Assays allowing the analysis of tumor angiogenesis are an essential tool to elucidate the role played by the tumor microenvironment in regulating tumor angiogenesis. The assays should also be capable of systematically investigating the effects of physiologically relevant, mechanical and chemical stimuli and their synergistic interactions. The high optical resolution of microfluidic assays facilitates three-dimensional studies of cellular morphogenesis. Their versatility can be applied to study the multi-parameter control of angiogenic factors.

Type
Chapter
Information
Integrative Mechanobiology
Micro- and Nano- Techniques in Cell Mechanobiology
, pp. 203 - 367
Publisher: Cambridge University Press
Print publication year: 2015

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