Book contents
- Frontmatter
- Contents
- List of figures
- List of tables
- List of contributors
- Foreword
- Acknowledgments
- 1 Introduction
- 2 Culture and psychopathology
- 3 Culture and ethnicity in psychopharmacotherapy
- 4 Ethnic differences in psychotropic drug response and pharmacokinetics
- 5 Pharmacogenetics of ethnic populations
- 6 Variation in psychotropic responses in the Chinese population
- 7 Variation in psychotropic responses in the Hispanic population
- 8 Identifying inter-ethnic variations in psychotropic response in African Americans and other ethnic minorities
- 9 Complementary medicines in mental disorders
- 10 Cultural factors and the use of psychotropic medications
- 11 Outpatient prescribing practices in Asian countries
- 12 Psychiatric inpatient psychotropic prescribing in East Asia
- 13 Pharmaco-economic implications for Asia and other economically disadvantaged countries
- 14 Integrating theory, practice and economics in psychopharmacology
- 15 Research directions in ethno-psychopharmacology
- Index
- References
6 - Variation in psychotropic responses in the Chinese population
Published online by Cambridge University Press: 22 August 2009
- Frontmatter
- Contents
- List of figures
- List of tables
- List of contributors
- Foreword
- Acknowledgments
- 1 Introduction
- 2 Culture and psychopathology
- 3 Culture and ethnicity in psychopharmacotherapy
- 4 Ethnic differences in psychotropic drug response and pharmacokinetics
- 5 Pharmacogenetics of ethnic populations
- 6 Variation in psychotropic responses in the Chinese population
- 7 Variation in psychotropic responses in the Hispanic population
- 8 Identifying inter-ethnic variations in psychotropic response in African Americans and other ethnic minorities
- 9 Complementary medicines in mental disorders
- 10 Cultural factors and the use of psychotropic medications
- 11 Outpatient prescribing practices in Asian countries
- 12 Psychiatric inpatient psychotropic prescribing in East Asia
- 13 Pharmaco-economic implications for Asia and other economically disadvantaged countries
- 14 Integrating theory, practice and economics in psychopharmacology
- 15 Research directions in ethno-psychopharmacology
- Index
- References
Summary
Psychopharmacotherapy in the Chinese population
Traditional medicine, especially herbal medicine and acupuncture, has a long history in China. Included in the voluminous classic literature of traditional Chinese medicine are specific acupuncture procedures and a large number of herbal formulas that have been regarded as useful for the treatment of mental disorders. Although most of these methods have not yet been examined with rigorous clinical trials, it does appear that, in general, they are likely to be effective in the treatment of mood disorders, but not psychotic disorders. Systematic settings to provide care for the severely mentally ill started in late nineteenth century. The first European styled mental hospital was established in Guangzhou, China, in 1898. Gradually more mental hospitals were established in other large cities in China. However, until the introduction of chlorpromazine in the 1950s, therapeutic options were extremely limited, and traditional Chinese medicine therapy, insulin coma, and electro-convulsive therapy (ECT) were commonly used for the treatment of severely disturbed patients.
As is true worldwide, the arrival of the phenothiazines in the 1950s heralded a new era for the treatment of psychotic disorders in China. The earliest antipsychotic medications used included rauwolfiae, reserpine, promazine, and acetylpromazine. In 1956, domestic chlorpromazine was produced in Shanghai. Based on open clinical trials and descriptive clinical case observations, the clinical profiles of these potent agents, including their efficacy and tolerability, were established in the Chinese populations.
- Type
- Chapter
- Information
- Ethno-psychopharmacologyAdvances in Current Practice, pp. 87 - 96Publisher: Cambridge University PressPrint publication year: 2008