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Part I - Background to understanding

Published online by Cambridge University Press:  05 April 2016

Keith Humphreys
Affiliation:
Stanford University School of Medicine, California
Anne Lingford-Hughes
Affiliation:
Imperial College London
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Edwards' Treatment of Drinking Problems
A Guide for the Helping Professions
, pp. 5 - 130
Publisher: Cambridge University Press
Print publication year: 2016

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References

References

American Psychiatric Association (APA). (2000). Diagnostic and statistical manual of mental disorders (4th edition, text revision). Washington DC: American Psychiatric Association.Google Scholar
American Psychiatric Association (APA). (2013). Diagnostic and statistical manual of mental disorders (5th edition). Washington DC: American Psychiatric Association.Google Scholar
Australian Institute of Health and Welfare. (2008). 2007 national drug strategy household survey: Detailed findings. Drug statistics series no. 20. Cat. no. PHE 98. Canberra, Australia: Australian Institute of Health and Welfare.Google Scholar
British Medical Association. (1995). Alcohol: Guidelines on sensible drinking. London: British Medical Association.Google Scholar
Chikritzhs, T., Catalano, P., Stockwell, T., Donath, S., Ngo, H. T., Young, D. J., & Matthews, S. (2003). Australian alcohol indicators 1990–2001: Patterns of alcohol use and related harms for Australian states and territories. Perth, Australia: National Drug Research Institute.Google Scholar
Dawson, D. A., Archer, L. D., & Grant, B. F. (1996). Reducing alcohol-use disorders via decreased consumption: A comparison of population and high-risk strategies. Drug and Alcohol Dependence, 42(1), 3947.CrossRefGoogle ScholarPubMed
Department of Health. (1995). Sensible drinking: The report of an inter-departmental working group. London: Department of Health.Google Scholar
Department of Health. (2016). Alcohol Guidelines Review – Report from the Guidelines development group to the UK Chief Medical Officers. London: Department of Health.Google Scholar
Edwards, G. (1986). The alcohol dependence syndrome: A concept as stimulus to enquiry. British Journal of Addiction, 81(2), 171183.CrossRefGoogle ScholarPubMed
Edwards, G., Arif, A., & Hodgson, R. (1981). Nomenclature and classification of drug- and alcohol-related problems: A WHO memorandum. Bulletin of the World Health Organization, 59(2), 225242.Google ScholarPubMed
Edwards, G., & Gross, M. M. (1976). Alcohol dependence: Provisional description of a clinical syndrome. British Medical Journal, 1(6017), 10581061.CrossRefGoogle ScholarPubMed
Hasin, D., Paykin, A., Meydan, J., & Grant, B. (2000). Withdrawal and tolerance: prognostic significance in DSM-IV alcohol dependence. Journal of Studies on Alcohol, 61(3), 431438.CrossRefGoogle ScholarPubMed
Kalinowski, A., & Humphreys, K. (in press). Governmental standard drink definitions and low-risk alcohol consumption guidelines in 37 countries. Addiction.Google Scholar
Lifestyle Statistics, Health and Social Care Information Centre. (2013). Statistics on alcohol: England, 2013. London: Health and Social Care Information Centre.Google Scholar
National Health and Medical Research Council. (2009). Australian guidelines to reduce health risks from drinking alcohol. Canberra, Australia: National Health and Medical Research Council.Google Scholar
National Institute on Alcohol Abuse and Alcoholism (NIAAA). (2015). Alcohol use disorder: A comparison of DSM-IV and DSM-5. NIH Publication 13–7999. Bethesda, MD: National Institutes of Health.Google Scholar
Rehm, J., Mathers, C., Popova, S., Thavorncharoensap, M., Teerawattananon, Y., & Patra, J. (2009). Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet, 373(9682), 22232233.Google Scholar
Schuckit, M. A., Smith, T. L., Daeppen, J. B., Daeppen, J. B., Eng, M., Li, T. K., … Bucholz, K. K. (1998). Clinical relevance of the distinction between alcohol dependence with and without a physiological component. American Journal of Psychiatry 155(6), 733740.Google ScholarPubMed
Trotter, T. (1804). An essay, medical, philosophical, and chemical, on drunkenness, and its effects on the human body. London: T. N. Longman and O. Rees.Google Scholar
Vale, B., & Edwards, G. (2011). Physician to the fleet: The life and times of Thomas Trotter, 1760–1832. Woodbridge, UK: Boydell Press.Google Scholar
World Health Organization (WHO). (1992). The ICD-10 classification of mental and behavioural disorders clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.Google Scholar
World Health Organization (WHO). (1994). Lexicon of alcohol and drug terms. Geneva: World Health Organization.Google Scholar
World Health Organization (WHO). (2009). Global health risks: Mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization.Google Scholar

References

Agarwal, D. P., & Goedde, H. W. (1990). Alcohol metabolism, alcohol intolerance, and alcoholism: Biochemical and pharmacogenetic approaches. Berlin: Springer.Google Scholar
Ball, D., Pembrey, M., & Stevens, D. N. (2007). Genomics. In Nutt, D., Robbins, T. W., Stimson, G. V., Ince, M., & Jackson, A. (Eds.), Drugs and the future (pp. 89131). London: Academic Press.Google Scholar
Beck, A., Schlagenhauf, F., Wüstenberg, T., Hein, J., Kienast, T., Kahnt, T., Schmack, K., Hägele, C., Knutson, B., Heinz, A., & Wrase, J. (2009). Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics. Biological Psychiatry, 66(8), 734742.Google Scholar
Birley, A. J., James, M. R., Dickson, P. A., Montgomery, G. W., Heath, A. C., Whitfield, J. B., & Martin, N. G. (2008). Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism. Human Molecular Genetics, 17(2), 179189.Google Scholar
Brick, J. (2004). Characteristics of alcohol: Chemistry, use, and abuse. In Brick, J. (Ed.), Handbook of the medical consequences of alcohol (pp. 16). New York: Haworth.Google Scholar
Butelman, E. R., Yuferov, V., & Kreek, M. J. (2012). κ-Opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction. Trends Neurosciences, 35(10), 587596.CrossRefGoogle ScholarPubMed
Chen, C. H., Ferreira, J. C., Gross, E. R., & Mochly-Rosen, D. (2014). Targeting aldehyde dehydrogenase 2: New therapeutic opportunities. Physiological Reviews, 94(1), 134.Google Scholar
Edwards, G., & Gross, M. M. (1976). Alcohol dependence: Provisional description of a clinical syndrome. British Medical Journal, 1(6017), 10581061.CrossRefGoogle ScholarPubMed
Erritzoe, D., Tziortzi, A., Bargiela, D., Colasanti, A., Searle, G. E., Gunn, R. N., … Lingford-Hughes, A. (2014). In vivo imaging of cerebral dopamine D3 receptors in alcoholism. Neuropsychopharmacology, 39(7), 17031712.Google Scholar
Fleming, M., Mihic, S. J., & Harris, R. A. (2006). Ethanol. In Brunton, L. L., Lazo, J., & Parker, K. L. (Eds.), Goodman and Gilman’s: The pharmacological basis of therapeutics (11th ed., pp. 591606). New York: McGraw Hill.Google Scholar
Heinz, A., Reimold, M., Wrase, J., Hermann, D., Croissant, B., Mundle, G., … Mann, K. (2005). Correlation of stable elevations in striatal μ-opioid receptor availability in detoxified alcoholic patients with alcohol craving: A positron emission tomography study using carbon 11-labeled carfentanil. Archives of General Psychiatry, 62(1), 5764.CrossRefGoogle ScholarPubMed
Hermann, D., Weber-Fahr, W., Sartorius, A., Hoerst, M., Frischknecht, U., Tunc-Skarka, N., … Sommer, W.H. (2012). Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biological Psychiatry, 71(11), 10151021.Google Scholar
Holmes, A., Spanagel, R., & Krystal, J. H. (2013). Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl), 229(3), 539554.CrossRefGoogle ScholarPubMed
Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014). Factors modulating neural reactivity to drug cues in addiction: A survey of human neuroimaging studies. Neuroscience & Biobehavioral Reviews, 38, 116.Google Scholar
Jelski, W., Chrostek, L., Szmitkowski, M., & Laszewicz, W. (2002). Activity of class I, II, III, and IV alcohol dehydrogenase isoenzymes in human gastric mucosa. Digestive Diseases and Sciences, 47(7), 15541557.CrossRefGoogle Scholar
Krystal, J. H., Staley, J., Mason, G., Petrakis, I. L., Kaufman, J., Harris, R.A., … Lappalainen, J. (2006). Gamma-aminobutyric acid type A receptors and alcoholism: Intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry, 63(9), 957968.CrossRefGoogle ScholarPubMed
Kumar, S., Porcu, P., Werner, D. F., Matthews, D. B., Diaz-Granados, J. L., Helfand, R. S., & Morrow, A. L. (2009). The role of GABA(A) receptors in the acute and chronic effects of ethanol: A decade of progress. Psychopharmacology (Berl), 205(4), 529564.CrossRefGoogle ScholarPubMed
Lingford-Hughes, A., Watson, B., Kalk, N., & Reid, A. (2010). Neuropharmacology of addiction and how it informs treatment. British Medical Bulletin, 96, 93110.Google Scholar
Lingford-Hughes, A. R., Welch, S., Peters, L., & Nutt, D. J. (2012). BAP updated guidelines: Evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: Recommendations from BAP. Journal of Psychopharmacology, 26(7), 899952.Google Scholar
Lingford-Hughes, A. R., Wilson, S. J., Cunningham, V. J., Feeney, A., Stevensen, B., Brooks, D. J., & Nutt, D. (2005). GABA-benzodiazepine receptor function in alcohol dependence: A combined 11C-flumazenil PET and pharmacodynamic study. Psychopharmacology, 180, 595606.Google Scholar
Martinez, D., & Narendran, R. (2010). Imaging neurotransmitter release by drugs of abuse. Current Topics in Behavioral Neurosciences, 3, 219245.Google Scholar
Mutschler, J., Abbruzzese, E., Witt, S. H., Dirican, G., Nieratschker, V., Frank, J., … Kiefer, F. (2012). Functional polymorphism of the dopamine β-hydroxylase gene is associated with increased risk of disulfiram-induced adverse effects in alcohol-dependent patients. Journal of Clinical Psychopharmacology, 32(4), 578580.Google Scholar
Monnig, M. A., Tonigan, J. S., Yeo, R. A., Thoma, R. J., & McCrady, B. S. (2013). White matter volume in alcohol use disorders: A meta-analysis. Addiction Biology, 18(3), 581592.Google Scholar
Nutt, D. (1999). Alcohol and the brain. Pharmacological insights for psychiatrists. British Journal of Psychiatry, 175, 114119.Google Scholar
Nutt, D., Lingford-Hughes, A., Erritzoe, D., & Stokes, P. R. (2015). The dopamine theory of addiction: 40 years of highs and lows. Nature Reviews Neuroscience, 16, 305–132.Google Scholar
Ramchandani, V. A., Umhau, J., Pavon, F. J., Ruiz-Velasco, V., Margas, W., Sun, H., … Heilig, M. (2011). A genetic determinant of the striatal dopamine response to alcohol in men. Molecular Psychiatry, 16(8):809817.Google Scholar
Rudolph, U., & Knoflach, F. (2011). Beyond classical benzodiazepines: Novel therapeutic potential of GABAA receptor subtypes. Nature Reviews Drug Discovery, 10(9), 685697.Google Scholar
Schacht, J. P., Anton, R. F., & Myrick, H. (2013). Functional neuroimaging studies of alcohol cue reactivity: A quantitative meta-analysis and systematic review. Addiction Biology, 18(1), 121133.Google Scholar
Sullivan, E. V., & Pfefferbaum, A. (2005). Neurocircuitry in alcoholism: A substrate of disruption and repair. Psychopharmacology, 180, 583594.Google Scholar
Tyacke, R. J., Lingford-Hughes, A., Reed, L. J., & Nutt, D. J. (2010). GABAB receptors in addiction and its treatment. Advances Pharmacology, 58, 373396.Google Scholar
van Holst, R. J., Clark, L., Veltman, D. J., van den Brink, W., & Goudriaan, A.E. (2014). Enhanced striatal responses during expectancy coding in alcohol dependence. Drug and Alcohol Dependence, 142, 204208.Google Scholar
Walker, B. M., & Koob, G. F. (2008). Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology, 33(3), 643652.Google Scholar
Ward, R. J., Lallemand, F., & de Witte, P. (2009). Biochemical and neurotransmitter changes implicated in alcohol-induced brain damage in chronic or “binge drinking” alcohol abuse. Alcohol and Alcoholism, 44(2), 128135.Google Scholar

References

Aiken, A., Wadolowski, M., Bruno, R., Najman, J., Kypri, K., Slade, T., … Mattick, R. P. (in press). Cohort profile: The Australian Parental Supply of Alcohol Longitudinal Study (APSALS). International Journal of Epidemiology.Google Scholar
Alcohol and Public Policy Group. (2010). Alcohol: No ordinary commodity – a summary of the second edition. Addiction, 105, 769779.Google Scholar
Anderson, P., & Baumberg, B. (2006). Alcohol in Europe. London: Institute of Alcohol Studies.Google Scholar
Anton, R. F., Oroszi, G., O’Malley, S., Couper, D., Swift, R., Pettinati, H., & Goldman, D. (2008). An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: Results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Archives of General Psychiatry, 65(2), 135144.Google Scholar
Cameron, D. (2013). Thoughts (and some data) on The Spirit Level. New Directions in the Study of Alcohol, 35, 2124.Google Scholar
Carlson, R. G. (2006). Ethnography and applied substance misuse research: Anthropological and cross-cultural factors. In Miller, W. R. & Carroll, K. (Eds.), Rethinking substance abuse: What the science shows and what we should do about it (pp. 97114). New York: Guilford.Google Scholar
Cook, P. J. (2007). Paying the tab: The costs and benefits of alcohol control. Princeton, NJ: Princeton University Press.Google Scholar
Ducci, F., & Goldman, D. (2008). Genetic approaches to addiction: Genes and alcohol. Addiction 103, 14141428.CrossRefGoogle ScholarPubMed
Edenberg, H. J., & Foroud, T. (2013). Genetics and alcoholism. Nature Reviews Gastroenterology and Hepatology, 10(8), 487494.CrossRefGoogle ScholarPubMed
Enoch, M. A. (2013). Genetic influences of the development of alcoholism. Current Psychiatry Reports, 11, 412.Google Scholar
Gruenewald, P. J., & Treno, A. J. (2000). Local and global alcohol supply: Economic and geographic models of community systems. The supply side initiative: International collaboration to study the alcohol supply. Addiction, 95(Suppl 4), 537549.Google Scholar
Hall, W. (2010). What are the policy lessons of National Alcohol Prohibition in the United States, 1920–1933? Addiction, 105, 11641173.Google Scholar
Hermens, D. F., Lagopoulos, J., Tobias-Webb, J., De Regt, T., Dore, G., Juckes, L., …. Hickie, I. B. (2013). Pathways to alcohol-induced brain impairment in young people: A review. Cortex, 49, 317.CrossRefGoogle ScholarPubMed
Hill, S. Y., De Bellis, M. D., Keshavan, M. S., Lowers, L., Shen, S., Hall, J., & Pitts, T. (2001). Right amygdala volume in adolescent and young adult offspring from families at high risk for developing alcoholism. Biological Psychiatry, 49(11), 894905.CrossRefGoogle Scholar
Hirschhorn, J. N., & Daly, M. J. (2005). Genome-wide association studies for common diseases and complex traits. Nature Review: Genetics, 6, 95108.Google Scholar
Humphreys, K., & Gifford, E. (2006). Religion, spirituality and the troublesome use of substances. In Miller, W. R. & Carroll, K. (Eds.), Rethinking substance abuse: What the science shows and what we should do about it (pp. 257274). New York: Guilford.Google Scholar
Humphreys, K., Moos, R. H., & Finney, J. W. (1996). Life domains, Alcoholics Anonymous, and role incumbency in the 3-year course of problem drinking. Journal of Nervous and Mental Disease, 184, 475481.CrossRefGoogle ScholarPubMed
Johnson, B. A., Seneviratne, C., Wang, X. Q., Ait-Daoud, N., & Li, M.D (2014). Determination of genotype combinations that can predict the outcome of the treatment of alcohol dependence using the 5-HT3 antagonist ondansetron. American Journal of Psychiatry, 170(9), 10201031.CrossRefGoogle Scholar
Kiernan, M., Toro, P. A., Rappaport, J., & Seidman, E. (1989). Economic predictors of mental health services utilization: A time-series analysis. American Journal of Community Psychology 17, 801820.Google Scholar
Kranzler, H. R., Covault, J., Feinn, R., Armeli, S., Tennen, H., Arias, A. J., … Kampman, KM. (2014). Topiramate treatment for heavy drinkers: Moderation by a GRIK1 polymorphism. American Journal of Psychiatry, 171(4), 445452.Google Scholar
Kyzar, E. J., & Pandey, S. C. (2015). Molecular mechanisms of synaptic remodeling in alcoholism. Neuroscience letters, 601, 1119.Google Scholar
Lembke, A. (2012). Time to abandon the self-medication hypothesis in patients with psychiatric disorders. American Journal of Drug and Alcohol Abuse, 38, 524529.CrossRefGoogle ScholarPubMed
Levey, D. F., Le-Niculescu, H., Frank, J., Ayalew, M., Jain, N., Kirlin, B., … Niculescu, A. B. (2014). Genetic risk prediction and neurobiological understanding of alcoholism. Translational Psychiatry, 20, e391.Google Scholar
MacAndrew, C., & Edgerton, R. B. (1970). Drunken comportment. London: Nelson.Google Scholar
Mäkelä, K. (1980). Differential effects of restricting the supply of alcohol: Studies of a strike in Finnish liquor stores. Journal of Drug Issues, 10, 131144.Google Scholar
Müller, K. U., Gan, G., Banaschewski, T., Barker, G. J., Bokde, A. L., Büchel, C., … IMAGEN Consortium. (2015). No differences in ventral striatum responsivity between adolescents with a positive family history of alcoholism and controls. Addiction Biology, 20, 534545.Google Scholar
NIAAA. (2013). Update on the genetics of alcoholism. Alcohol Research: Current Reviews, 34(3), 261380.Google Scholar
Nunes, E. V., & Levin, F. R. (2004). Treatment of depression in patients with alcohol or other drug dependence: A meta-analysis. JAMA, 291, 18871896.CrossRefGoogle ScholarPubMed
Ooteman, W., Naassila, M., Koeter, M. W., Verheul, R., Schippers, G.M., Houchi, H., … van den Brink, W. (2009). Predicting the effect of naltrexone and acamprosate in alcohol-dependent patients using genetic indicators. Addiction Biology, 14(3), 328337.Google Scholar
Oslin, D. W., Leong, S. H., Lynch, K. G., Berrettini, W., O’Brien, C. P., Gordon, A. J., & Rukstalis, M. (2015). Naltrexone vs placebo for the treatment of alcohol dependence: A randomized clinical trial. JAMA Psychiatry, 72, 430437.Google Scholar
Rietschel, M., & Treutlein, J. (2013). The genetics of alcohol dependence. Annals of the New York Academy of Sciences, 1282(1), 3970.Google Scholar
Spadoni, A. D., Simmons, A. N., Yang, T. T., & Tapert, S. F. (2013). Family history of alcohol use disorders and neuromaturation: A functional connectivity study with adolescents. American Journal of Drug and Alcohol Abuse, 39(6), 356364.Google Scholar
Zhao, J., Stockwell, T., Martin, G., Macdonald, S., Vallance, K., Treno, A., … Buxton, J. (2013). The relationship between minimum alcohol prices, outlet densities and alcohol-attributable deaths in British Colombia. Addiction, 108, 10591069.Google Scholar

References

Babor, T., Caetano, R., Casswell, S., Edwards, G., Giesbrecht, N., Graham, K., … Room, R. (2010). Alcohol: No ordinary commodity: Research and public policy (2nd edition). Oxford: Oxford University Press.CrossRefGoogle Scholar
Devries, K. M., Child, J. C., Bacchus, L. J., Mak, J., Falder, G. Graham, K., … Heise, L. (2013). Intimate partner violence victimization and alcohol consumption in women: A systematic review and meta-analysis. Addiction, 109, 379391.CrossRefGoogle ScholarPubMed
DuPont, R. L., McLellan, A. T., White, W. L., Merlo, L. J., & Gold, M. S. (2009). Setting the standard for recovery: Physicians health programs. Journal of Substance Abuse Treatment, 36, 159171.Google Scholar
Goodliffe, J. (1994). Alcohol and depression in England and American lawyer disciplinary proceedings. Addiction, 89, 12371244.Google Scholar
Graham, P., & West, P. (2001). Alcohol and crime: Examining the link. In Heather, N., Peters, T. J., & Stockwell, T. (Eds.), International handbook of alcohol dependence and problems (pp. 439470). Chester, UK: John Wiley & Sons.Google Scholar
Griffin, M. L., Amodeo, M., Fassler, I., Ellis, M. A., & Clay, C. (2005). Mediating factors for the long-term effects of parental alcoholism in women: The contribution of other childhood stresses and resources. American Journal on Addictions, 14, 1834.Google Scholar
Grucza, R. A., Bucholz, K. K., Rice, J. P., & Bierut, L. J. (2008). Secular trends in the lifetime prevalence of alcohol dependence in the United States: A re-evaluation. Alcoholism: Clinical and Experimental Research, 32(5), 763770.Google Scholar
Heinz, A. J., Beck, A., Meyed-Lindenberg, A., Sterzer, P., & Heinz, A. (2011). Cognitive and neurobiological mechanisms of alcohol-related aggression. Nature Reviews Neuroscience, 12, 400413.Google Scholar
Hingson, R., & Winter, M. (2003). Epidemiology and consequences of drinking and driving. Bethesda, MD: National Institute on Alcohol Abuse and Alcoholism. http://pubs.niaaa.nih.gov/publications/arh27–1/63–78.htmGoogle Scholar
Jacob, T., & Johnson, S. (1997). Parenting influences on the development of alcohol abuse and dependence. Alcohol Health and Research World, 21, 204209.Google Scholar
Jones, S., Casswell, S., & Zhang, J. F. (1995). The economic costs of alcohol-related absenteeism and reduced productivity among the working population of New Zealand. Addiction, 90(11), 14551461.Google Scholar
Mäkelä, P., Rossow, I., & Tryggvesson, K. (2002). Who drinks more and less when policies change? The evidence from 50 years of Nordic studies. In Room, R. (Ed.), The effects of Nordic alcohol policies. Helsinki: Nordic Council for Alcohol and Drug Research.Google Scholar
Miller, M. A., & Fillmore, M. T. (2014). Cognitive and behavioral preoccupation with alcohol in recidivist DUI offenders. Journal of Studies on Alcohol, 75, 10181022.Google ScholarPubMed
Moos, R. H., Finney, J. W., & Cronkite, R. C. (1990). Alcoholism treatment: Context, process and outcome. New York: Oxford University Press.Google Scholar
Orford, J., Natera, G., Mora, J., et al. (2005). Coping with alcohol and drug problems: The experiences of family members in three contrasting cultures. Hove, UK: Routledge.Google Scholar
Reich, W., Earls, F., & Powell, J. (1988). A comparison of the home and social environments of children of alcoholic and non-alcoholic parents. British Journal of Addiction, 83, 831839.Google Scholar
Steinglass, P., Bennett, L. A., Wolin, S. J., & Reiss, D. (1987). The alcoholic family. London: Hutchinson.Google Scholar
Velleman, R., & Orford, R. (1999). Risk and resilience: Adults who were the children of problem drinkers. Amsterdam: Harwood.Google Scholar

References

Abel, E. L., & Sokol, R. J. (1991). A revised conservative estimate of the incidence of FAS and its economic impact. Alcoholism: Clinical and Experimental Research, 15, 514524.Google Scholar
Babor, T., Caetano, R., Casswell, S., Edwards, G., Giesbrecht, N., Graham, K., … Room, R. (2010). Alcohol: No ordinary commodity (2nd ed.). Oxford: Oxford University Press.Google Scholar
Baliunas, D., Rehm, J., Irving, H., & Shuper, P. (2010). Alcohol consumption and risk of incident human immunodeficiency virus infection: A meta-analysis. International Journal of Public Health, 55, 159166.Google Scholar
Baliunas, D. O., Taylor, B. J., Irving, H., Roerecke, M., Patra, J., Mohapatra, S., & Rehm, J. (2009). Alcohol as a risk factor for type 2 diabetes. Diabetes Care, 32, 21232132.Google Scholar
Beilin, L. J., & Puddey, I. B. (2006). Alcohol and hypertension: An update. Hypertension, 47, 10351038.Google Scholar
Bofetta, P., & Hashibe, M. (2006). Alcohol and cancer. Lancet Oncology, 7, 149156.Google Scholar
Bråthen, G., Ben-Menachem, E., Brodtkorb, E., Galvin, R., Garcia-Monco, J. C., Halasz, P., … EFNS Task Force on Diagnosis and Treatment of Alcohol-Related Seizures. (2005). EFNS guideline on the diagnosis and management of alcohol-related seizures: Report of an EFNS task force. European Journal of Neurology, 12, 575581.Google Scholar
British Medical Association Board of Science. (2007). Fetal alcohol spectrum disorders – A guide for healthcare professionals. London: British Medical Association.Google Scholar
British Medical Association Board of Science. (2008). Alcohol misuse: Tackling the UK epidemic. London: British Medical Association.Google Scholar
Brock, C., Nielsen, L. M., Lelic, D., & Drewes, A. M. (2013). Pathophysiology of chronic pancreatitis. World Journal of Gastroenterology, 19(42), 7231.Google Scholar
Chen, L., Davey Smith, G., Harbord, R. M., & Lewis, S. J. (2008). Alcohol intake and blood pressure: A systematic review implementing a Mendelian randomization approach. PLoS Medicine, 5(3), e52.Google Scholar
Choi, H. K., Atkinson, K., Karlson, E. W., Willett, W., & Curhan, G. (2004). Alcohol intake and risk of incident gout in men: A prospective study. Lancet, 363, 12771281.Google Scholar
Chou, S. P., Grant, B. F., & Dawson, D. A. (1998). Alcoholic beverage preference and risks of alcohol-related medical consequences: A preliminary report from the National Longitudinal Alcohol Epidemiologic Study. Alcohol: Clinical and Experimental Research, 22, 14501455.Google Scholar
Cook, C. C., Hallwood, P. M., & Thomson, A. D. (1998). B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol and Alcoholism, 33(4), 317336.CrossRefGoogle ScholarPubMed
Cook, R. T. (1998). Alcohol abuse, alcoholism, and damage to the immune system – a review. Alcoholism: Clinical and Experimental Research, 22, 19271942.Google Scholar
Corrao, G., Bagnardi, V., Zambon, A., & Arico, S. (1999). Exploring the dose-responsive relationship between alcohol consumption and the risk of several alcohol-related conditions – a meta analysis. Addiction, 94, 15511573.Google Scholar
Costanzo, S., Di Castelnuovo, A., Donati, M. B., Iacoviello, L., & de Gaetano, G. (2010). Alcohol consumption and mortality in patients with cardiovascular disease: A meta-analysis. Journal of the American College of Cardiology, 55(13), 13391347.Google Scholar
Druesne-Pecollo, N., Tehard, B., Mallet, Y., Gerber, M., Norat, T., Hercberg, S., & Latino-Martel, P. (2009). Alcohol and genetic polymorphisms: Effect on risk of alcohol-related cancer. Lancet Oncology, 10(2), 173180.Google Scholar
Esper, L. H., & Furtado, E. F. (2014). Identifying maternal risk factors associated with fetal alcohol spectrum disorders: A systematic review. European Child & Adolescent Psychiatry, 23(10), 877889.Google Scholar
Estruch, R. (2001). Nutrition and infectious disease. In Heather, N., Peters, T. J., & Stockwell, T. (Eds.), International handbook of alcohol problems and dependence (pp. 185204). Chichester, UK: John Wiley & Sons.Google Scholar
Franke, A., Teyssen, S., & Singer, M. V. (2005). Alcohol-related diseases of the esophagus and stomach. Digestive Diseases, 23(3–4), 204213.Google Scholar
Hazeldine, S., & Sheron, N. (2014). Current treatment options for alcohol-related liver disease. Current Opinion in Gastroenterology, 30(3), 238244.Google Scholar
Hendershot, C. S., Stoner, S. A., Pantalone, D. W., & Simoni, J. M. (2009). Alcohol use and antiretroviral adherence: Review and meta-analysis. Journal of Acquired Immune Deficiency Syndrome, 52, 180202.Google Scholar
Hermens, D. F., Lagopoulos, J., Tobias-Webb, J., De Regt, T., Dore, G., Juckes, L., … Hickie, I. B. (2013). Pathways to alcohol-induced brain impairment in young people: A review. Cortex, 49(1), 317.Google Scholar
Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., … InterAct Consortium. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. British Medical Journal, 349, g4164.Google Scholar
Hvidtfeldt, U. A., Tolstrup, J. S., Jakobsen, M. U., Heitmann, B. L., Grønbaek, M., O’Reilly, E., … Ascherio, A. (2010). Alcohol intake and risk of coronary heart disease in younger, middle-aged, and older adults. Circulation, 121(14), 15891597.Google Scholar
International Agency for Research on Cancer. (1998). Alcohol drinking, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans (vol. 44). Lyon, France: International Agency for Research on Cancer.Google Scholar
Klatsky, A. L., Armstrong, M. A., Friedman, G. D., & Sidney, S. (2001). Alcohol drinking and risk of hospitalization for ischemic stroke. American Journal of Cardiology, 88(6), 703706.Google Scholar
Kopelman, M. D., Thomson, A. D., Guerrini, I., & Marshall, E. J. (2009). The Korsakoff syndrome: Clinical aspects, psychology and treatment. Alcohol and Alcoholism, 44(2), 148154.Google Scholar
Krige, J. E. J., & Beckingham, I. J. (2001). ABC of diseases of liver, pancreas, and biliary system: Portal hypertension – 2. Ascites, encephalopathy, and other conditions. British Medical Journal, 322(7283), 416.Google Scholar
Lamminpaa, A. (1995). Alcohol intoxication in childhood and adolescence. Alcohol and Alcoholism, 30, 512.Google ScholarPubMed
Lieber, C. S. (1988). The influence of alcohol on nutritional status. Nutrition Review, 46, 241254.Google Scholar
Lishman, W. A. (1981). Cerebral disorders in alcoholism. Brain, 104, 120.Google Scholar
Lishman, W. A. (1998). Organic psychiatry: The psychological consequences of cerebral disorder, 3rd ed. Oxford: Blackwell Scientific Publications.Google Scholar
Lucey, M. R. (2014). Liver transplantation for alcoholic liver disease. Nature Reviews Gastroenterology & Hepatology, 11(5), 300307.Google Scholar
McLeod, R., Stockwell, T., Stevens, M., & Phillips, M. (1999). The relationship between alcohol consumption patterns and injury. Addiction, 94, 17191734.Google Scholar
Mukamal, K. J., Chung, H., Jenny, N. S., Kuller, L. H., Longstreth, W. T., Mittleman, M. A., … Siscovick, D. S. (2005b). Alcohol use and risk of ischaemic stroke among older adults: The cardiovascular health study. Stroke, 36, 18301834.Google Scholar
Mukamal, K. J., Tolstrup, J. S., Friberg, J., Jensen, G., & Grønbaek, M. (2005a). Alcohol consumption and risk of atrial fibrillation in men and women: The Copenhagen City Heart Study. Circulation, 112, 17361742.Google Scholar
Murray, C. J. L, Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., … Memish, Z. A. (2012). Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859), 21972223.Google Scholar
National Institute for Health and Clinical Excellence. (2008). National Collaborating Centre for Women’s and Children’s Health. Antenatal care: Routine care for the healthy pregnant woman, 2nd ed. London: RCOG Press.Google Scholar
O’Keefe, J. H., Bhatti, S. K., Bajwa, A., DiNicolantonio, , & Lavie, C. J. (2014, March). Alcohol and cardiovascular health: The dose makes the poison … or the remedy. Mayo Clinic Proceedings, 89(3), 382393.Google Scholar
Preedy, V. R., Mantle, D., & Peters, T. J. (2001). Alcoholic muscle, skin and bone disease. In Heather, N., Peters, T. J., & Stockwell, T. (Eds.), International handbook of alcohol problems and dependence (pp. 169184). Chichester, UK: John Wiley & Sons.Google Scholar
Ramayya, A., & Jauhar, P. (1997). Increasing incidence of Korsakoff ’s psychosis in the east end of Glasgow. Alcohol and Alcoholism, 32, 281285.Google Scholar
Rehm, J., Room, R., Monteiro, M., Gmel, G., Graham, K., Rehn, N., … Jernigan, D. (2004). Alcohol use. In Ezzati, M., Lopez, A. D., Rodgers, A., & Murray, C. J. L. (Eds.), Comparative quantification of health risks: Global and regional burden of disease due to selected major risk factors (vol. 1., pp. 9591109). Geneva: World Health OrganizationGoogle Scholar
Room, R., Babor, T., & Rehm, J. (2005). Alcohol and public health. Lancet, 65, 519530.Google Scholar
Rubin, E., & Urbano-Marquez, A. (1994). Alcoholic cardiomyopathy. Alcoholism: Clinical and Experimental Research, 18, 111114.CrossRefGoogle ScholarPubMed
Stewart, S., Latham, P. K., Miller, P. M., Randall, P., & Anton, R. E. (2008). Blood pressure reduction during treatment for alcohol dependence: Results from the Combining Medications and Behavioural Interventions for Alcoholism (COMBINE) study. Addiction, 103, 16221628.Google Scholar
Sullivan, E. V., & Pfefferbaum, A. (2005). Neurocircuitry in alcoholism: A substrate of disruption and repair. Psychopharmacology, 180(4), 583594.Google Scholar
Thomson, A. D., Cook, C. C. H., Guerrini, I., Sheedy, D., Harper, C., & Marshall, E. J. (2008). Wernicke’s encephalopathy: “Plus ca change, plus c’est la meme chose.” Alcohol and Alcoholism, 43, 180186.Google Scholar
Thomson, A. D., & Marshall, E. J. (2006). The natural history of Wernicke’s encephalopathy and Korsakoff ’s psychosis. Alcohol and Alcoholism, 41, 151158.Google Scholar
Thompson, P. L. (2013). J-curve revisited: Cardiovascular benefits of moderate alcohol use cannot be dismissed. Medical Journal of Australia, 198(8), 419422.Google Scholar
Tønnesen, H. (1999). The alcohol patient and surgery. Alcohol and Alcoholism, 34, 148152.Google Scholar
Tønnesen, H., Rosenberg, J., Nielsen, H. J., Rasmussen, V., Hauge, C., Pedersen, I. K., & Kehlet, H. (1999). Effect of preoperative abstinence on poor postoperative outcome in alcohol misusers: Randomised controlled trial. British Medical Journal, 318, 13111316.Google Scholar
Urbano-Marquez, A., Estruch, R., Fernandez-Sola, J., Nicolas, J. M., Pare, J. C., & Rubin, E. (1995). The greater risk of alcoholic cardiomyopathy and myopathy in women compared with men. Journal of the American Medical Association, 274, 149154.Google Scholar
Victor, M., Adams, R. D., & Collins, G. H. (1971). The Wernicke–Korsakoff syndrome. Philadelphia, PA: F. A. Davis.Google Scholar
Walker, R. K., Cousins, V. M., Umoh, N. A., Jeffress, M. A., Taghipour, D., Al-Rubaiee, M., & Haddad, G. E. (2013). The good, the bad, and the ugly with alcohol use and abuse on the heart. Alcoholism: Clinical and Experimental Research, 37(8), 12531260.Google Scholar
Whiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., … Vos, T. (2013). Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010. Lancet, 382(9904), 15751586.Google Scholar
Williams, R., Aspinall, R., Bellis, M., Camps-Walsh, G., Cramp, M., Dhawan, A., … Smith, T. (2014). Addressing liver disease in the UK: A blueprint for attaining excellence in health care and reducing premature mortality from lifestyle issues of excess consumption of alcohol, obesity, and viral hepatitis. Lancet, 384, 19531997.CrossRefGoogle Scholar
World Cancer Research Fund/American Institute for Cancer Research. (2007). Food, nutrition, physical activity, and the prevention of cancer: A global perspective. Washington DC: American Institute for Cancer Research.Google Scholar
World Health Organization. (2007). WHO Expert Committee on Problems Related to Alcohol Consumption. Second Report. WHO Technical Report Series 944. Geneva: World Health Organization.Google Scholar
World Health Organization. (2011). Global status report on alcohol and health. Geneva, Switzerland: World Health Organization.Google Scholar
Xin, X., He, J., Frontini, M. G., Motsamai, O.I., & Whelton, P.K. (2001). Effects of alcohol reduction on blood pressure: A meta-analysis of randomized controlled trials. Hypertension, 38(5), 11121117.Google Scholar
Zahr, N. M., Kaufman, K. L., & Harper, C. G. (2011). Clinical and pathological features of alcohol-related brain damage. Nature Reviews Neurology, 7, 284294.Google Scholar

References

Blanco, C., Xu, Y., Brady, K., Pérez-Fuentes, G., Okuda, M., & Wang, S. (2013). Comorbidity of posttraumatic stress disorder with alcohol dependence among US adults: Results from National Epidemiological Survey on Alcohol and Related Conditions. Drug and Alcohol Dependence, 132, 630638.Google Scholar
Boden, J. M., & Fergusson, D. M. (2011). Alcohol and depression. Addiction, 106, 906–14.Google Scholar
Brady, J. (2006). The association between alcohol misuse and suicidal behaviour. Alcohol and Alcoholism, 41, 473478.Google Scholar
Breslau, N., Chilcoat, H. D., Kessley, R. C., & Davis, G. C. (1999). Previous exposure to trauma: Results from the Detroit Area Survey of Trauma. American Journal of Psychiatry, 156, 902907.Google Scholar
Burns, L., Teesson, M., & Lynskey, M. (2001). The epidemiology of comorbidity between alcohol use disorders and mental disorders in Australia: Findings from the National Survey of Mental Health & Well-Being (Technical Report 118). Sydney, Australia: National Drug and Alcohol Research Centre.Google Scholar
Chiappetta, V., García-Rodríguez, O., Jin, C. J., Secades-Villa, & R., Blanco, C. (2014). Predictors of quit attempts and successful quit attempts among individuals with alcohol use disorders in a nationally representative sample. Drug and Alcohol Dependence, 141, 138144.Google Scholar
Crome, I., Brown, A., Dar, K., Harris, L., Janikiewicz, S., Rao, T., … Tarbuck, A. (2011). Our invisible addicts: First report of the Older Persons’ Substance Misuse Working Group of the Royal College of Psychiatrists. London: Royal College of Psychiatrists.Google Scholar
Duke, P., Pantelis, C., & Barnes, T. R. E. (1994). South Westminster Schizophrenia Survey. Alcohol use and its relationship to symptoms, tardive dyskinesia and illness onset. British Journal of Psychiatry, 164, 630636.Google Scholar
Farrell, M., Howes, S., Bebbington, P., Brugha, T., Jenkins, R., Lewis, G., … Meltzer, H. (2001). Nicotine, alcohol and drug dependence, and psychiatry morbidity – results of a national household survey. British Journal of Psychiatry, 179, 432437.Google Scholar
Farren, C. K., Hill, K. P., & Weiss, R. D. (2012). Bipolar disorder and alcohol use disorder: A review. Current Psychiatry Reports, 14, 659666.Google Scholar
Fazel, S., Långström, N., Hjern, A., Grann, M., & Lichtenstein, P. (2009). Schizophrenia, substance abuse and violent crime. Journal of the American Medical Association, 301, 20162023.Google Scholar
Fombonne, E. (1998). Suicidal behaviours in vulnerable adolescents. British Journal of Psychiatry, 173, 154159.Google Scholar
Franko, D. L., Keshaviah, A., Eddy, K. T., Krishna, M., Davis, M. C., Keel, P. K., & Herzog, D. B. (2013). A longitudinal investigation of mortality in anorexia nervosa and bulimia nervosa. American Journal of Psychiatry, 170(8), 917925.Google Scholar
Frye, M. A., & Salloum, I. M. (2006). Bipolar disorder and comorbid alcoholism: Prevalence rate and treatment considerations. Bipolar Disorder, 8(6), 677685.Google Scholar
Glass, I. (1989a). Alcoholic hallucinosis: A psychiatric enigma – I. The development of an idea. British Journal of Addiction, 84, 2941.Google Scholar
Glass, I. (1989b). Alcoholic hallucinosis: A psychiatric enigma – 2. Follow-up studies. British Journal of Addiction, 84, 151164.Google Scholar
Goodwin, D. W., Crane, B. J., & Guze, S. B. (1969a). Phenomenological aspects of the alcoholic “blackout.” British Journal of Psychiatry, 115, 10331038.Google Scholar
Goodwin, D. W., Crane, B. J., & Guze, S. B. (1969b). Alcoholic “blackouts”: A review and clinical study of 100 alcoholics. American Journal of Psychiatry, 126, 191198.Google Scholar
Grant, B. F., Stinson, F. S., Dawson, D. A., Chuo, S. P., Dufour, M. C., Compton, W., … Kaplan, K. (2004). Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. Archives of General Psychiatry, 61, 807816.Google Scholar
Gregorowski, C., Seedat, S., & Jordaan, G. P. (2013). A clinical approach to the assessment and management of co-morbid eating disorders and substance use disorders. BMC Psychiatry, 13, 289.Google Scholar
Hasin, D., & Kilcoyne, B. (2012). Comorbidity of psychiatric and substance use disorders in the United States: Current issues and findings from the NESARC. Current Opinion in Psychiatry, 25(3), 165.Google Scholar
Hawton, K., Bergen, H., Casey, D., Simkin, S., Palmer, B., Cooper, J., … Owens, D. (2007). Self-harm in England: A tale of three cities. Multicentre study of self-harm. Social Psychiatry and Psychiatric Epidemiology, 42, 513521.Google Scholar
Helzer, J. E., & Pryzbeck, T. R. (1988). The co-occurrence of alcoholism with other psychiatric disorders in the general population and its impact on treatment. Journal of Studies on Alcohol, 49, 219224.Google Scholar
Humphreys, K., Weingardt, K. R., Horst, D., Joshi, A. A., & Finney, J. W. (2005). Prevalence and predictors of research participant eligibility criteria in alcohol treatment outcome studies, 1970–98. Addiction, 100, 12491257.Google Scholar
Inskip, H. M., Harris, E. C., & Barraclough, B. (1998). Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia. British Journal of Psychiatry, 172, 3537.Google Scholar
Jenkins, R. (2007). Substance use and suicidal behaviour. Psychiatry, 6, 1922.Google Scholar
Johnston, A. L., Thevos, A. K., Randall, C. L., & Anton, R. F. (1991). Increased severity of alcohol withdrawal in in-patient alcoholics with a co-existing anxiety diagnosis. British Journal of Addiction, 86, 719725.Google Scholar
Kessler, R. C., Crum, R. M., & Warner, L. A. (1997). Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Study. Archives of General Psychiatry, 54, 313321.Google Scholar
Kessler, R. C., McGonagle, K. A., Zhad, S., Nelson, C. B., Hughes, M., Eshleman, S., … Kendler, K. S. (1994). Lifetime and 12-month prevalence of DSM-III psychiatric disorders in the United States: Results from the National Comorbidity Survey. Archives of General Psychiatry, 51, 819.Google Scholar
Khan, S., Okuda, M., Hasin, D. S., Secades-Villa, R., Keyes, K., Lin, K. H., … Blanco, C. (2013). Gender differences in lifetime alcohol dependence: Results from the national epidemiologic survey on alcohol and related conditions. Alcoholism: Clinical and Experimental Research, 37, 16961705.Google Scholar
Lembke, A. (2012). Time to abandon the self-medication hypothesis in patients with psychiatric disorders. American Journal of Drug and Alcohol Abuse, 38, 524529.Google Scholar
Lishman, W. A. (1998). Organic psychiatry (3rd ed.). Oxford: Blackwell Scientific.Google Scholar
Menezes, P., Johnson, S., Thornicroft, G., Marshall, J., Prosser, D., Bebbington, P., & Kuipers, E. (1996). Drug and alcohol problems among individuals with severe mental illness in South London. British Journal of Psychiatry, 168, 612619.Google Scholar
Murphy, G. G., & Wetzel, R. D. (1990). The lifetime risk of suicide in alcoholism. Archives of General Psychiatry, 47, 383392.Google Scholar
Ohlmeier, M. D., Peters, K., Kordon, A., Seifert, J., Wildt, B. T., Wiese, B., … Schneider, U. (2007). Nicotine and alcohol dependence in patients with comorbid attention-deficit/hyperactivity disorder (ADHD). Alcohol and Alcoholism, 42, 539543.Google Scholar
Pacek, L. R., Martins, S. S., & Crum, R. M. (2013). The bidirectional relationships between alcohol, cannabis, co-occurring alcohol and cannabis use disorders with major depressive disorder: Results from a national sample. Journal of Affective Disorders, 148, 188195.Google Scholar
Pirkola, S., Marttunen, M. J., Henriksson, M. M., Isometsa, E. T., Heikkinen, M. E., & Lönnqvist, J. K. (1999). Alcohol-related problems among adolescent suicides in Finland. Alcohol and Alcoholism, 34, 320329.Google Scholar
Pirkola, S. P., Suominen, K., & Isometsa, E. T. (2004). Suicide in alcohol-dependent individuals: Epidemiology and management. CNS Drugs, 18, 423436.Google Scholar
Rossow, I., Romelsjö, A., & Leifman, H. (1999). Alcohol abuse and suicidal behaviour in young and middle-aged men: Differentiating between attempted and completed suicide. Addiction, 94, 11991207.Google Scholar
Roy, A. (1996). Aetiology of secondary depression in male alcoholics. British Journal of Psychiatry, 169, 753757.Google Scholar
Roy, A., DeJong, J., Lamparski, D., George, T., & Linnoila, M. (1991). Depression among alcoholics. Archives of General Psychiatry, 48, 428432.Google Scholar
Schuckit, M. A. (2014). Recognition and management of withdrawal delirium (delirium tremens). New England Journal of Medicine, 371(22), 21092113.CrossRefGoogle ScholarPubMed
Spencer, T. J., Biederman, J., & Mick, E. (2007). Attention-deficit/hyperactivity disorder: Diagnosis, lifespan, comorbidities and neurobiology. Journal of Pediatric Psychology, 32, 631642.Google Scholar
Stepp, S. D., Trull, T. J., & Sher, K. J. (2005). Borderline personality features predict alcohol use problems. Journal of Personality Disorders, 19, 711722.Google Scholar
Swendsen, J., Conway, K. P., Degenhardt, L., Glantz, M., Jin, R., Merikangas, K. R., … Kessler, R. C. (2010). Mental disorders as risk factors for substance use, abuse and dependence: Results from the 10-year follow-up of the National Comorbidity Survey. Addiction, 105, 11171128.Google Scholar
Thoma, P., & Daum, I. (2013). Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings. Psychiatry and Clinical Neurosciences, 67(6), 367383.Google Scholar
Tsuang, J. W., Irwin, M. R., Smith, T. L., & Schuckit, M. A. (1994). Characteristics of men with alcoholic hallucinosis. Addiction, 89, 7378.Google Scholar
Vassilas, C. A., & Morgan, H. G. (1997). Suicide in Avon. Life stress, alcohol misuse and use of services. British Journal of Psychiatry, 170, 453455.Google Scholar
Volkow, N. D., Wang, G. J., Tomasi, D., & Baler, R. D. (2013). The addictive dimensionality of obesity. Biological Psychiatry, 73(9), 811818.Google Scholar
Weaver, T., Rutter, D., Madden, P., Ward, J., Stimson, G., & Renton, A. (2001). Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: Prevalence and service needs in an inner London borough. Social Psychiatry and Psychiatric Epidemiology, 36, 399406.Google Scholar
World Health Organization. (1992). The ICD-10 classification of mental and behavioural disorders. Geneva: Author.Google Scholar
Wu, L. T., & Blazer, D. G. (2014). Substance use disorders and psychiatric comorbidity in mid and later life: A review. International Journal of Epidemiology, 43(2) 304317.Google Scholar

References

Apantaku-Olajide, T., Darker, C. D., & Smyth, B. P. (2013). Onset of cocaine use: Associated alcohol intoxication and psychosocial characteristics among adolescents in substance abuse treatment. Journal of Addiction Medicine, 7, 183188.Google Scholar
Babor, T. F. (2004). Brief treatments for cannabis dependence: Findings from a randomized multisite trial. Journal of Consulting and Clinical Psychology, 72(3), 455.Google Scholar
Barrett, S. P., Darredeau, C., & Pihl, R. O. (2006). Patterns of simultaneous polysubstance use in drug using university students. Human Psychopharmacology: Clinical and Experimental, 21, 255263.Google Scholar
Brady, K. T., Sonne, E., Randall, C. L., Adinoff, B., & Malcolm, R. (1995). Features of cocaine dependence with concurrent alcohol use. Drug and Alcohol Dependence, 39, 6971.Google Scholar
Carroll, K. M., Nich, C., Ball, S. A., McCance, E., & Rounsavile, B. J. (1998). Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram. Addiction, 93, 713728.Google Scholar
Carroll, K. M., Nich, C., Ball, S. A., McCance, E., Frankforter, T. L., & Rounsaville, B. J. (2000). One-year follow-up of disulfiram and psychotherapy for cocaine-alcohol users: Sustained effects of treatment. Addiction, 95, 13351349.CrossRefGoogle ScholarPubMed
Carroll, K. M., Power, M. -E. D., Bryant, K., & Rounsaville, B. (1993). One-year follow-up status of treatment-seeking cocaine abusers. Journal of Nervous and Mental Disease, 181, 7179.Google Scholar
Carroll, K. M., Rounsaville, B. J., & Bryant, K. J. (1993). Alcoholism in treatment seeking cocaine abusers: Clinical and prognostic significance. Journal of Studies on Alcohol, 54, 199208.Google Scholar
Carter, J. L., Strang, J., Frissa, S., Hayes, R. D., SELCoH Study Team, Hatch, S. L., & Hotopf, M. (2013). Comparisons of polydrug use at national and inner city levels in England: Associations with demographic and socioeconomic factors. Annals of Epidemiology, 23, 636–45.Google Scholar
Chick, J., & Nutt, D. J. (2012). Substitution therapy for alcoholism: Time for a reappraisal? Journal of Psychopharmacology, 26(2), 205212.Google Scholar
Ciraulo, D. A., & Nace, E. P. (2000). Benzodiazepine treatment of anxiety or insomnia in substance abuse patients. American Journal on Addictions, 9(4), 276284.Google Scholar
Ciraulo, D. A., Sands, B. F., & Shader, R. I. (1988). Critical review of liability for benzodiazepine abuse among alcoholics. American Journal of Psychiatry, 145, 15011506.Google Scholar
Connor, J. P., Gullo, M. J., White, A., & Kelly, A. B. (2014). Polysubstance use: Diagnostic challenges, patterns of use and health. Current Opinion in Psychiatry, 27, 269–75Google Scholar
Crome, I., Brown, A., Dar, K., Janikiewicz, S., Rao, T., & Tarbuck, A. (2011). Our invisible addicts: First report of the Older Persons’ Substance Misuse Working Group of the Royal College of Psychiatrists. London: Royal College of Psychiatrists.Google Scholar
Daeppen, J. -B., Smith, T. L., Danko, G. P., Gordon, L., Landi, N. A., Nurnberger, J. I. Jr, … Schuckit, M. A. (2000). Clinical correlates of cigarette smoking and nicotine dependence in alcohol dependent men and women. Alcohol and Alcoholism, 35, 171175.Google Scholar
Darke, S., Degenhardt, L., & Mattick, R. (2007). Mortality amongst illicit drug users: Epidemiology, causes and intervention. Cambridge: Cambridge University Press.Google Scholar
Daskalopoulou, M., Rodger, A., Phillips, A. N., Sherr, L., Speakman, A., Collins, S., … Lampe, F. C. (2014). Recreational drug use, polydrug use, and sexual behaviour in HIV-diagnosed men who have sex with men in the UK: Results from the cross-sectional ASTRA study. Lancet HIV, 1, e22e31.Google Scholar
Dreifuss, J. A., Griffin, M. L., Frost, K., Fitzmaurice, G. M., Potter, J. S., Fiellin, D. A., … Weiss, R. D. (2013). Patient characteristics associated with buprenorphine/naloxone treatment outcome for prescription opioid dependence: Results from a multisite study. Drug and Alcohol Dependence, 131(1), 112118.Google Scholar
European Monitoring Centre for Drugs and Drug Addiction. (2009). Polydrug use: Patterns and responses. Luxembourg: Office for Official Publications of the European Communities.Google Scholar
Fiore, M. C., Jaén, C. R., Baker, T. B., Bailey, W. C., Bennett, G., Benowitz, N. L., … Williams, C. (2009). Treating tobacco use and dependence: 2008 Update. Quick reference guide for clinicians. Rockville, MD: U.S. Department of Health and Human Services.Google Scholar
Gossop, M. (2001). A web of dependence. Addiction, 96, 677678.Google Scholar
Gossop, M., Manning, V., & Ridge, G. (2006). Concurrent use of alcohol and cocaine: Differences in patterns of use and problems among users of crack cocaine and cocaine powder. Alcohol and Alcoholism, 41, 121125.Google Scholar
Grant, B., & Dawson, D. (1997). Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey. Journal of Substance Abuse, 9, 103110.Google Scholar
Han, C., McGue, M. K., & Iacono, W. G. (1999). Lifetime tobacco, alcohol and other substance use in adolescent Minnesota twins: Univariate and multivariate behavioural genetic analyses. Addiction, 94, 981993.Google Scholar
Harris, J., Best, D., Man, L. H., Welch, S., Gossop, M., & Strang, J. (2000). Change in cigarette smoking among alcohol and drug misusers during in-patient detoxification. Addiction Biology, 5, 443450.Google Scholar
Hartman, R., Brown, T., Milavetz, G., Spurgin, A., Pierce, R. S., Gorelick, D. A., Gaffney, G., & Huestis, M. A. (2015). Cannabis effects on driving lateral control with and without alcohol. Drug and Alcohol Dependence, 154, 2537Google Scholar
Hayford, K. E., Patten, C. A., Rummans, T. A., Schroeder, D. R., Offord, K. P., Croghan, I. T., … Hurt, R. D. (1999). Efficacy of bupropion for smoking cessation in smokers with a former history of major depression or alcoholism. British Journal of Psychiatry, 174, 173178.Google Scholar
Heil, S. H., Badger, G. J., & Higgins, S. T. (2001). Alcohol dependence among cocaine-dependent outpatients: Demographics, drug use, treatment outcome and other characteristics. Journal of Studies on Alcohol, 62, 1422.Google Scholar
Herbst, E. D., Harris, D. S., Everhart, E. T., Mendelson, J., Jacob, P., & Jones, R. T. (2011). Cocaethylene formation following ethanol and cocaine administration by different routes. Experimental and Clinical Psychopharmacology, 19, 95104.Google Scholar
Humphreys, K., Blodgett, J. C., & Roberts, L. W. (2015). The exclusion of people with psychiatric disorders from medical research. Journal of Psychiatric Research, 70, 2832.Google Scholar
Humphreys, K., & Gifford, E. (2006). Religion, spirituality and the troublesome use of substances. In Miller, W. R. & Carroll, K. (Eds.), Rethinking substance abuse: What the science shows and what we should do about it (pp. 257274). New York: Guilford.Google Scholar
Joint Formulary Committee. (2015). British National Formulary (BNF) 69. London: BMJ Publishing Group Ltd and Royal Pharmaceutical Society.Google Scholar
Kalman, D., Herz, L., Monti, P., Kahler, C. W., Mooney, M., Rodrigues, S., & O’Connor, K. (2011). Incremental efficacy of adding bupropion to the nicotine patch for smoking cessation in smokers with a recent history of alcohol dependence: Results from a randomized, double-blind, placebo-controlled study. Drug and Alcohol Dependence, 118, 111118.Google Scholar
Karam-Hage, M., Strobbe, S., Robinson, J. D., & Brower, K. J. (2011). Bupropion-SR for smoking cessation in early recovery from alcohol dependence: A placebo-controlled, double-blind pilot study. American Journal of Drug and Alcohol Abuse, 37, 487490.Google Scholar
Kedia, S., Sell, M. A., & Relyea, G. (2007). Mono-versus polydrug abuse patterns among publicly funded clients. Substance Abuse Treatment, Prevention and Policy, 2, 33.Google Scholar
Kelly, A. B., Chan, G. C., White, A., Saunders, J. B., Baker, P. J., & Connor, J. P. (2014). Is there any evidence of changes in patterns of concurrent drug use among young Australians 18–29 years between 2007 and 2010?. Addictive Behaviors, 39(8), 12491252.Google Scholar
Lembke, A., & Humphreys, K. (2015). A call to include people with mental illness and substance use disorders alongside “regular” smokers in smoking cessation research. Tobacco Control. Advance online publication. doi:10.1136/tobaccocontrol-2014-052215Google Scholar
Leri, F., Bruneau, J., & Stewart, J. (2003). Understanding polydrug use: Review of heroin and cocaine co-use. Addiction, 98, 722.Google Scholar
Le Strat, Y., Ramoz, N., & Gorwood, P. (2010). In alcohol-dependent drinkers, what does the presence of nicotine dependence tell us about psychiatric and addictive disorders comorbidity? Alcohol and Alcoholism, 45(2), 167172.Google Scholar
Lingford-Hughes, A. R., Welch, S., Peters, L., Nutt, D. J., & British Association for Psychopharmacology, Expert Reviewers Group. (2012). BAP updated guidelines: Evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: Recommendations from BAP. Journal of Psychopharmacology, 26, 899952.Google Scholar
Madden, P. A., & Heath, A. C. (2002). Shared genetic vulnerability in alcohol and cigarette use dependence. Alcoholism: Clinical and Experimental Research, 26, 19191921.Google Scholar
Martin, C. S., Clifford, P. R., Maisto, S. A., Earleywine, M., Kirisci, L., & Longabaugh, R. (1996). Polydrug use in an inpatient treatment sample of problem drinkers. Alcoholism: Clinical and Experimental Research, 20, 413417.Google Scholar
Martin, G., Macdonald, S., Pakula, B., & Roth, E. A. (2014). A comparison of motivations for use among users of crack cocaine and cocaine powder in a sample of simultaneous cocaine and alcohol users. Addictive Behaviors, 39, 699702.Google Scholar
McCabe, S. E., Cranford, J. A., & Boyd, C. J. (2006). The relationship between past-year drinking behaviours and non-medical use of prescription drugs: Prevalence of co-occurrence in a national sample. Drug and Alcohol Dependence, 84, 281288.CrossRefGoogle Scholar
McKee, S. A., & Weinberger, A. H. (2013). How can we use our knowledge of alcohol-tobacco interactions to reduce alcohol use? Annual Review of Clinical Psychology, 9, 649674.Google Scholar
McKetin, R., Chalmers, J., Sunderland, M., & Bright, D. A. (2014). Recreational drug use and binge drinking: Stimulant but not cannabis intoxication is associated with excessive alcohol consumption. Drug and Alcohol Review, 33, 436445.Google Scholar
Midanik, L. T., Tam, T. W., & Weisner, C. (2007). Concurrent and simultaneous drug and alcohol use: Results of the 2000 National Alcohol Survey. Drug and Alcohol Dependence, 90, 7280.Google Scholar
Moss, H. B., Chen, C. M., & Yi, H. Y. (2014). Early adolescent patterns of alcohol, cigarettes, and marijuana polysubstance use and young adult substance use outcomes in a nationally representative sample. Drug and Alcohol Dependence, 136, 5162.Google Scholar
Myers, M. G., & Kelly, J. F. (2006). Cigarette smoking among adolescents with alcohol and other drug use problems. Alcohol Research and Health, 29, 221227.Google Scholar
National Highway Traffic Safety Administration. (1999). Marijuana & alcohol combined increase impairment (Traffic Safety Facts Banner No. 201). Washington, DC: U.S. Department of Transportation.Google Scholar
NICE, National Institute for Health and Clinical Excellence. (2004). Zaleplon, zolpidem and zopiclone for the management of insomnia (NICE technology appraisal guidance 77). London: Author.Google Scholar
NICE, National Institute for Health and Clinical Excellence. (2013). Smoking cessation in secondary care: Acute, maternity and mental health services (NICE Public Health Guidance 48). London: Author.Google Scholar
Nocente, R., Vitali, M., Balducci, G., Enea, D., Kranzler, H. R., & Ceccanti, M. (2013). Varenicline and neuronal nicotinic acetylcholine receptors: A new approach to the treatment of co-occurring alcohol and nicotine addiction? American Journal on Addictions, 22, 453459.Google Scholar
Olfson, M., King, M., & Schoenbaum, M. (2015). Benzodiazepine use in the United States. JAMA Psychiatry, 72, 136142.Google Scholar
Otomanelli, G. (1999). Methadone patients and alcohol abuse [review]. Journal of Substance Abuse Treatment, 16, 113121.Google Scholar
Pelucchi, C., Gallus, S., Garavello, W., Bosetti, C., & La Vecchia, C. (2006). Cancer risk associated with alcohol and tobacco use: Focus on upper aero-digestive tract and liver. Alcohol Research & Health, 29, 193198.Google Scholar
Pettinati, H. M., Kampman, K. M., Lynch, K. G., Xie, H., Dackis, C., Rabinowitz, A. R., & O’Brien, C. P. (2008). A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependence. Addictive Behaviors, 33, 651667.Google Scholar
Prochaska, J. J., Delucchi, K., & Hall, S. M. (2004). A meta-analysis of smoking cessation interventions with individuals in substance abuse treatment or recovery. Journal of Consulting and Clinical Psychology, 72(6), 1144.Google Scholar
Roux, P., Lions, C., Michel, L., Cohen, J., Mora, M., Marcellin, F., … ANRS Methaville Study Group. (2014). Predictors of non-adherence to methadone maintenance treatment in opioid-dependent individuals: Implications for clinicians. Current Pharmaceutical Design, 20, 40974105.Google Scholar
Rubio, G., Manzanares, J., Jiménez, M., Rodríguez-Jiménez, R., Martínez, I., Iribarren, M.M., … Palomo, T. (2008). Use of cocaine by heavy drinkers increases vulnerability to developing alcohol dependence: A 4-year follow-up study. Journal of Clinical Psychiatry, 69, 563570.Google Scholar
Schifano, F. (2014). Misuse and abuse of pregabalin and gabapentin: Cause for concern? CNS Drugs, 28, 491496.Google Scholar
Smith, G. W., Farrell, M., Bunting, B. P., Houston, J. E., & Shevlin, M. (2011). Patterns of polydrug use in Great Britain: Findings from a national household population survey. Drug and Alcohol Dependence, 113, 222228.Google Scholar
Srivastava, A., Kahan, M., & Ross, S. (2008). The effect of methadone maintenance treatment on alcohol consumption: A systematic review. Journal of Substance Abuse Treatment, 34, 215223.Google Scholar
Staines, G. L., Magura, S., Foote, J., Deluca, A., & Kosanke, N. (2001). Polysubstance use among alcoholics. Journal of Addictive Disorders, 20, 5369.Google Scholar
Substance Abuse and Mental Health Services Administration (SAMHSA). (2002). The DASIS (Drug and Alcohol Services Information System) report: Polydrug admissions – 2002. Rockville, MD: Office of Applied Studies.Google Scholar
United Nations Office on Drugs and Crime (UNODC). (2014). World drug report 2014 (United Nations publication, Sales No. E.14.XI.7). Vienna: United Nations.Google Scholar
West, R. (2001). Multiple substance dependence: Implications for treatment of nicotine dependence. Addiction, 96, 775776.Google Scholar

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