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Section 5 - Optic Neuritis in Children

Published online by Cambridge University Press:  11 April 2011

Dorothée Chabas
Affiliation:
University of California, San Francisco
Emmanuelle L. Waubant
Affiliation:
University of California, San Francisco
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Summary

This chapter reviews the presentation of children with optic neuritis (ON) and compares these children to the 457 adults enrolled across the 15 institutions who participated in the ON treatment trial (ONTT). ON is part of a broader category of disorders, collectively referred to as the optic neuropathies, causing dysfunction of the optic nerve. Acute demyelinating ON may occur as a clinically isolated syndrome as in adults, or it may be concurrent with widespread demyelination as in acute disseminated encephalomyelitis. Visual recovery is usually good in children with ON. The ONTT has a tremendous impact on the use of multiple sclerosis (MS) therapies in adults with ON and other clinically isolated syndromes. Treatment is based on adult studies and includes short-term and long-term therapies, which may hasten some aspects of visual recovery and decrease the disease burden and risk of MS, respectively.
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Publisher: Cambridge University Press
Print publication year: 2011

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  • Optic Neuritis in Children
  • Edited by Dorothée Chabas, University of California, San Francisco, Emmanuelle L. Waubant, University of California, San Francisco
  • Book: Demyelinating Disorders of the Central Nervous System in Childhood
  • Online publication: 11 April 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511974373.021
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  • Optic Neuritis in Children
  • Edited by Dorothée Chabas, University of California, San Francisco, Emmanuelle L. Waubant, University of California, San Francisco
  • Book: Demyelinating Disorders of the Central Nervous System in Childhood
  • Online publication: 11 April 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511974373.021
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Optic Neuritis in Children
  • Edited by Dorothée Chabas, University of California, San Francisco, Emmanuelle L. Waubant, University of California, San Francisco
  • Book: Demyelinating Disorders of the Central Nervous System in Childhood
  • Online publication: 11 April 2011
  • Chapter DOI: https://doi.org/10.1017/CBO9780511974373.021
Available formats
×