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Chapter 17 - Heart Transplantation

from Section 2 - Anaesthesia for Specific Procedures

Published online by Cambridge University Press:  12 May 2020

By
Lenore F. van der Merwe  and
Alan D. Ashworth
Edited by
Joseph Arrowsmith ,
Andrew Roscoe  and
Jonathan Mackay
Joseph Arrowsmith
Affiliation:
Royal Papworth Hospital, Cambridge
Andrew Roscoe
Affiliation:
Singapore General Hospital
Jonathan Mackay
Affiliation:
Royal Papworth Hospital, Cambridge
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Summary

The first successful human-to-human heart transplant was performed by Christiaan Barnard in 1967 but the initial outcomes were poor. The introduction of ciclosporin resulted in a significant improvement in survival, leading to an increase in heart transplantation through the 1980s. A total of 5,149 heart transplants, including 4,547 adult transplants, were performed at 302 transplant centres worldwide in the year to July 2017, with 86% 1-year survival, just over 50% survival at 10 years and a median survival of 11 years.

Type
Chapter
Information
Core Topics in Cardiac Anaesthesia , pp. 125 - 130
Publisher: Cambridge University Press
Print publication year: 2020

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References

Further Reading

Banner, NR, Bonser, RS, Clark, AL, et al. UK guidelines for referral and assessment of adults for heart transplantation. Heart 2011; 97: 1520–7.CrossRefGoogle ScholarPubMed
Costanzo, MR, Dipchand, A, Starling, R, et al. International Society for Heart Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant 2010; 29: 914–56.CrossRefGoogle ScholarPubMed
Fischer, S, Glas, K. A review of cardiac transplantation. Anesthesiology Clin 2013; 31: 383–403.CrossRefGoogle ScholarPubMed
International Society for Heart and Lung Transplantation. International Thoracic Organ Transplant (TTX) Registry data slides. https://ishltregistries.org/registries/slides.asp (accessed December 2018).Google Scholar
Kobashigawa, J, Zuckermann, A, Macdonald, P, et al. ISHLT Consensus: report from a consensus conference on primary graft dysfunction after cardiac transplantation. J Heart Lung Transplant 2014; 33: 327–40.Google Scholar
Lund, LH, Edwards, LB, Kucheryavaya, AY, et al. The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Heart Transplantation Report – 2015; focus theme: early graft failure. J Heart Lung Transplant 2015; 34: 1244–54.CrossRefGoogle ScholarPubMed
Mehra, MR, Canter, CE, Hannan, MM, et al. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: a 10-year update. J Heart Lung Transplant 2016; 35: 1-23.CrossRefGoogle ScholarPubMed
Messer, S, Page, A, Axell, R, et al. Outcome after heart transplantation from donation after circulatory-determined death donors. J Heart Lung Transplant 2017; 36: 1311–18.CrossRefGoogle ScholarPubMed
Petit, SJ, Kydd, A. Heart transplantation. In Valchanov, K, Jones, N, Hogue, CW (eds), Core Topics in Cardiothoracic Critical Care, 2nd edn. Cambridge: Cambridge University Press; 2018. pp. 333–9.Google Scholar
Ramakrishna, H, Jaroszewski, DE, Arabia, FA. Adult cardiac transplantation: a review of perioperative management Part I. Ann Card Anaesth 2009; 12: 71–8.Google ScholarPubMed
Ramakrishna, H, Rehfeldt, KH, Pajaro, OE. Anesthetic pharmacology and perioperative considerations for heart transplantation. Curr Clin Pharmacol 2015; 10: 3–21.Google Scholar
Yancy, CW, Jessup, M, Bozkurt, B, et al. 2013 ACCF/AHA Guideline for the Management of Heart Failure. Circulation 2013; 128: e20–e327.Google ScholarPubMed

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