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Enhanced Biocompatibility of GPC by Ion Implantation and Deposition

Published online by Cambridge University Press:  26 February 2011

Robert Lee Zimmerman ,
Ismet Gürhan ,
Claudiu I. Muntele ,
Daryush Ila ,
Feyzan Özdal-Kurt  and
B. H. Sen
Robert Lee Zimmerman
Affiliation:
leslie@cim.aamu.edu, Alabama A&M University, Physics Department, 3900 Meridian Street, Normal, Alabama, 35762, United States, 256 653 2134, 256 372 5868
Ismet Gürhan
Affiliation:
ismetgurhan@yahoo.com, Ege University Faculty of Engineering, Department of Bioengineering, Turkey
Claudiu I. Muntele
Affiliation:
claudiu@cim.aamu.edu, Alabama A&M University, Physics Department, United States
Daryush Ila
Affiliation:
ila@cim.aamu.edu, Alabama A&M University, Physics Department, United States
Feyzan Özdal-Kurt
Affiliation:
feyzanozdalkurt@yahoo.com, Celal Bayar University Faculty of Science and Arts, Department of Biology, Turkey
B. H. Sen
Affiliation:
ismetgurhan@yahoo.com, Ege University Faculty of Dentistry, Turkey
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Abstract

Biocompatible Glassy Polymeric Carbon (GPC) is used for artificial heart valves and in other biomedical applications. Although it is ideally suited for implants in the blood stream, tissue that normally forms around the moving parts of a GPC heart valve sometimes loses adhesion and creates embolisms downstream. Here we compare silver ion implantation and silver deposition, each of which strongly inhibits cell attachment on GPC. Inhibition of cell adhesion is a desirable improvement to current GPC cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that traces of silver can favorably influence the surface of GPC for biomedical applications.

Keywords

Cbiomedicalion-beam assisted deposition
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 908: Symposium OO – Growth, Modification, and Analysis by Ion Beams at the Nanoscale , 2005 , 0908-OO16-04
Copyright
Copyright © Materials Research Society 2006

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