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Prediction of the excretion of allantoin and total purine derivatives by sheep from the ‘creatinine coefficient’

Published online by Cambridge University Press:  27 March 2009

G. J. Faichney ,
R. J. Welch  and
G. H. Brown
G. J. Faichney
Affiliation:
CSIRO, Division of Animal Production
R. J. Welch
Affiliation:
CSIRO, Division of Animal Production
G. H. Brown
Affiliation:
CSIRO, IAPP Biometrics Unit, Locked Bag 1, Blacktown, NSW 2148, Australia
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Summary

The urinary excretions of creatinine, allantoin and total purine derivatives by Merino ewes were compared with predictions based on the assumptions that creatinine excretion scaled to liveweight (the creatinine coefficient) was constant and was not affected by diet. The creatinine coefficient varied between individuals and was found to be affected by diet (P<0·01). As a result, there were systematic deviations (p<0·01) in the predictions of allantoin and total purine derivative excretion. If predictions of purine derivative excretion are to be made for individual animals in the absence of total urine collections, prior determination of individual creatinine coefficients is required and predictions may be confounded by diet effects on creatinine excretion. Predictions for groups on the basis of general relationships between the creatinine coefficient and liveweight may be subject to errors between diets of > 10%.

Type
Animals
Information
The Journal of Agricultural Science , Volume 125 , Issue 3 , December 1995 , pp. 425 - 428
Copyright
Copyright © Cambridge University Press 1995

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References

AFRC (1993). Energy and Protein Requirements of Ruminants. AFRC Technical Committee on Responses to Nutrients. Wallingford: CAB International.Google Scholar
Brody, S. (1945). Bioenergetics and Growth. New York: Reinhold Publishing Corporation.Google Scholar
Chen, X. B., Hovell, F. D. DeB., Ørskov, E. R. & Brown, D. S. (1990 a). Excretion of purine derivatives by ruminants: effect of exogenous nucleic acid supply on purine derivative excretion by sheep. British Journal of Nutrition 63, 131–142.CrossRefGoogle ScholarPubMed
Chen, X. B., Mathieson, J., Hovell, F. D. DeB. & Reeds, P. J. (1990 b). Measurement of purine derivatives in urine of ruminants using automated methods. Journal of the Science of Food and Agriculture 53, 23–33.CrossRefGoogle Scholar
Chen, X. B., Abdulrazak, S. A., Shand, W. J. & Ørskov, E. R. (1992). The effect of supplementing straw with barley or unmolassed sugar-beet pulp on microbial protein supply in sheep estimated from purine derivative excretion. Animal Production 55, 413–417.Google Scholar
Corbeil, R. R. & Searle, S. R. (1976). Restricted maximum likelihood (REML) estimation of variance components in the mixed model. Technometrics 18, 31–38.CrossRefGoogle Scholar
Dinning, J. S., Gallup, W. D. & Briggs, H. M. (1949). Excretion of creatinine and creatine by beef steers. Journal of Biological Chemistry 177, 157–161.CrossRefGoogle ScholarPubMed
Faichney, G. J. & White, G. A. (1983). Methods for the Analysis of Feeds Eaten bv Ruminants. Melbourne: CSIRO.Google Scholar
Folin, O. (1905). Laws governing the composition of urine. American Journal of Physiology 13, 66–115.CrossRefGoogle Scholar
Giesecke, D., Stangassinger, M. & Tiemeyer, W. (1984). Nucleic acid digestion and urinary purine metabolites in sheep nourished by intragastric infusions. Canadian Journal of Animal Science 64 (supplement), 144–145.CrossRefGoogle Scholar
Haeckel, R. (1981). Assay of creatinine in serum, with use of Fuller's earth to remove interferents. Clinical Chemistry 27, 179–183.CrossRefGoogle ScholarPubMed
Han, Y. K., Shin, H. T. & Landis, J. (1992). Effect of level of feed intake on the excretion of purine derivatives and purine derivatives to creatinine ratio in the urine of sheep. Asian-Australasian Journal of Animal Science 5, 465–468.CrossRefGoogle Scholar
Hawk, P. B., Oser, B. L. & Summerson, W. H. (1954). Practical Physiological Chemistry, 13th edn. New York: The Blackiston Company Inc.Google Scholar
Hovell, F. D. DeB., Ørskov, E. R., MacLeod, N. A. & McDonald, I. (1983). The effect of changes in the amount of energy infused as volatile fatty acids on the nitrogen retention and creatinine excretion of lambs wholly nourished by intragastric infusion. British Journal of Nutrition 50, 331–343.CrossRefGoogle ScholarPubMed
Lindberg, J. E., Bristav, H. & Manyenga, A. R. (1989). Excretion of purines in the urine of sheep in relation to duodenal flow of microbial protein. Swedish Journal of Agricultural Research 19, 45–52.Google Scholar
Puchala, R. & Kulasek, G. W. (1992). Estimation of microbial protein flow from the rumen of sheep using microbial nucleic acid and urinary excretion of purine derivatives. Canadian Journal of Animal Science 72, 821–830.CrossRefGoogle Scholar
Topps, J. H. & Elliott, R. C. (1965). Relationship between concentrations of ruminal nucleic acids and excretion of purine derivatives by sheep. Nature, London 205, 498–499.CrossRefGoogle Scholar
Van Niekerk, B. D. H., Bensadoun, A., Paladines, O. L. & Reid, J. T. (1963). A study of some of the conditions affecting the rate of excretion and stability of creatinine in sheep urine. Journal of Nutrition 79, 373–380.CrossRefGoogle ScholarPubMed
Verbic, J., Chen, X. B., MacLeod, N. A. & Ørskov, E. R. (1990). Excretion of purine derivatives by ruminants. Effect of microbial nucleic acid infusion on purine derivative excretion by steers. Journal of Agricultural Science, Cambridge 114, 243–248.CrossRefGoogle Scholar
Walker, D. M. & Faichney, G. J. (1964). Nitrogen balance studies with the milk-fed lamb. 2. The partition of urinary nitrogen and sulphur. British Journal of Nutrition 18, 201–207.CrossRefGoogle ScholarPubMed