An experiment was conducted at four locations during 1990 and 1991 to determine the response of cotton to 1.12 kg ai ha-1 of clomazone applied PPI in combination with in-furrow application of 0.50 kg ai ha-1 of aldicarb plus 0.14, 0.28, and 0.56 kg ai ha-1 of either disulfoton or phorate. Early-season cotton injury ranged from 15 to 63% with clomazone plus aldicarb. Stands were reduced 31 and 61% at two locations, and yield was reduced 50% at one location. Applied in combination with aldicarb, all three rates of disulfoton and 0.28 and 0.56 kg ha-1 of phorate protected cotton from clomazone injury. Phorate at 0.14 kg ha-1 partially protected cotton from clomazone injury.