To determine the competitiveness of common cocklebur (Xanthium pensylvanicum Wallr.) with cotton (Gossypium hirsutum L. 'Stoneville 213′), experiments were conducted on a Lucedale fine sandy loam from 1978 through 1980. Common cocklebur dry weight increased with increasing density up to 16 plants/15 m of row. No further increase in dry matter occurred beyond this density. Regression analysis showed that common cocklebur produced an average of 342 kg/ha of dry weight for each plant per 15-m row. Seed-cotton yields decreased as weed density increased up to 16 common cocklebur plants/15 m of row. Regression equations revealed yield losses ranging from 72 to 115 kg/ha for hand-harvested seed cotton and 57 to 90 kg/ha for machine-harvested seed cotton for each common cocklebur plant/15 m of row. Cotton stem diameter and height were reduced by weed competition in the same manner as seed cotton yields, but reductions were not as pronounced, indicating that these parameters were not good indicators of common cocklebur competition.