Remote sensing is a powerful method to reconstruct annual mass-balance series over past decades by exploiting archives of available images, as well as to study glaciers in inaccessible regions. We present the application of a methodological framework based only on optical satellite images to retrieve glacier-wide annual mass balances for 30 glaciers in the French Alps. The glacier-wide annual mass balance for the period 1983–2014 was reconstructed by combining changes in glacier volumes computed from remote-sensing derived DEMs with annual measurements of the snow line altitude on satellite images. Data from direct observations on two of the glaciers confirmed the accuracy of the annual mass balances quantified by remote sensing with an average difference of ~0.3 m w.e., within the uncertainty range of the methods. Our results confirm the significant increase in mass loss since the early 2000s, with a difference >1 m w.e. a−1 between the periods 1983–2002 and 2003–14. The region-wide mass balance for the French Alps over the period 1979–2011 was −0.66 ± 0.27 m w.e. a−1, close to that of the European Alps. We also show that changes in glacier surface area or length are not representative of changes in mass balance at the scale of a few decades.