Mainstream social science, when it looks for parallels with the natural sciences, tends to look to classical Physics, which stresses laws, causes, and theories. I argue that we should look instead to Biology, which explains principally with processes, mechanisms, and models. Here I look briefly at Evolutionary Biology and Developmental Biology, where reductionist gene-centric explanatory programs have failed – decisively and spectacularly (and relatively recently). Evolution involves not just genes (let alone selfish genes) but multilevel processes of modular tinkering, very much like what I have called continuous (trans)formation, including processes of co-evolution that are strikingly analogous to what we see in the social world. Similarly, gene expression, rather than a largely mechanical DNA-directed bottom-up process, is as much a matter of manipulating and transforming genetic material as it is processing the information that it contains. Gene expression can only be properly performed within multiple, complexly intertwined, self-organizing regulatory networks. More broadly, I argue that Systems Biology, which is on the cutting edge of twenty-first-century Biology, provides an attractive model for relational/systemic social sciences.