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This chapter presents the clinical history, examination, and the results of the procedures performed on a 30-year-old male shift worker who was admitted for the evaluation of uncontrolled daytime sleepiness and generalized muscle hypotonic attacks. The patient was also falling to the ground without loss of consciousness. The chapter presents the clinical history, examination, follow-up, treatment, diagnosis, and the results of the procedures performed on the patient. The results of polysomnography (PSG) showed that the patient had a total sleep time of 400 minutes and a total wake time of 40 minutes, with a sleep efficiency of 91%. The diagnosis was narcolepsy with cataplexy. Sodium oxybate was administered in increasing doses, and the progression after a year and a half was satisfactory; no episodes of cataplexy occurred during regular work hours. After 4 months of treatment with sodium oxybate, the patient did not complain of daytime sleepiness.
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