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Anthropometric studies have given much attention to the impact of industrialization and urbanization on the biological standards of living of urban populations. Instead, we know less about the evolution of height and the disparities within the rural world and how they have changed during the modern economic growth process. This article analyzes the evolution and the determining factors that would explain the inequality of the biological welfare of a group of rural populations in Mediterranean Spain. Using a database of the heights of military conscripts (N = 146,041) of the study area, a comparison is made of the biological well-being of the cohorts born between 1840 and 1965 in different rural environments (irrigated vs. dry farming). The results show that the recruits residing in irrigated areas were taller than those in dry farming areas and that the nutritional differences were greater among the latter. The advantage of the heights in irrigated areas widened with the development of commercial agriculture at the end of the nineteenth century and, although it began to reduce from the early decades of the twentieth century, the anthropometric gap persisted throughout the period analyzed. The data also suggest that the distribution of income was also more unequal in the dry farming areas, where the diet was less varied and rich than in the irrigated areas. This situation could be largely explained by the existence of low productivity agriculture in these dry farming areas, among other possible factors.
Chapter 3 is devoted to the theory of heights, which is fundamental in Diophantine geometry. We explain archimedean and nonarchimedean absolute values on a number field, and prove the product formula. We define the absolute (logarithmic) Weil height. We explain heights associated to line bundles, and prove Northcott’s finiteness theorem. In the latter part of Chapter 3, we briefly introduce abelian varieties and some properties of line bundles on abelian varieties, such as the seesaw theorem and the theorem of cube. We define Neron–Tate height pairings on abelian varieties. We introduce Jacobian varieties and the Abel–Jacobi maps. We prove the Hermite–Minkowski theorem and the Mordell–Weil theorem.
The Mordell conjecture (Faltings's theorem) is one of the most important achievements in Diophantine geometry, stating that an algebraic curve of genus at least two has only finitely many rational points. This book provides a self-contained and detailed proof of the Mordell conjecture following the papers of Bombieri and Vojta. Also acting as a concise introduction to Diophantine geometry, the text starts from basics of algebraic number theory, touches on several important theorems and techniques (including the theory of heights, the Mordell–Weil theorem, Siegel's lemma and Roth's lemma) from Diophantine geometry, and culminates in the proof of the Mordell conjecture. Based on the authors' own teaching experience, it will be of great value to advanced undergraduate and graduate students in algebraic geometry and number theory, as well as researchers interested in Diophantine geometry as a whole.
Research on paternal investment and child growth and development is limited outside of high-income countries. Using nationally representative data from low-resource Serbian Roma communities, this study examined father investment (direct care), its predictors and the associations between paternal investment, stepfather presence and child physical growth and early development. The sample included 1222 children aged 35–59 months, out of which 235 were living with biological fathers. Child outcomes included height-for-age Z-scores, stunting and early child developmental score. Roma paternal investment was relatively low. There was a positive association of father investment and children's height, and no association with developmental score. The presence of father vs. stepfather did not exert any influence on children. Instead, maternal and child characteristics explained both the overall development and height for Roma children. Thus, older children, born to literate, lower parity mothers of higher status and greater investment had better developmental and growth outcomes; girls were the preferred sex, owing to expected fitness benefits. Reverse causality emerged as the most likely pathway through which the cross-sectional association of father direct care with child growth may manifest, such that Roma fathers tend to bias their investment towards taller, more endowed children, because of greater fitness pay-off.
Tiafenacil is a new nonselective, protoporphyrinogen IX oxidase–inhibiting pyrimidinedione herbicide that is under consideration for registration to control grass and broadleaf weeds in corn, soybean, wheat, cotton, and other crops prior to crop emergence. The sensitivity of dry beans to tiafenacil is not known. Four field experiments were completed at Exeter and Ridgetown, ON, Canada, during the 2019 and 2020 growing seasons, to determine the sensitivity of azuki, kidney, small red, and white beans to tiafenacil applied preemergence (PRE) at 12.5, 25, 50, and 100 g ai ha−1. Tiafenacil applied at 100 g ai ha−1 caused 5% or less injury to azuki, kidney, small red, and white beans: 0% to 3% injury to azuki bean; 1% to 5% injury to kidney bean; and 1% to 4% injury to both small red bean and white bean. Tiafenacil applied PRE at 12.5, 25, 50, and 100 g ai ha−1 caused up to 1%, 4%, 4%, and 5% visible dry bean injury, respectively, but had no negative effect on other measured growth parameters including seed yield. Crop injury was generally greatest when tiafenacil was appled at the 100 g ai ha−1 rate in dry beans. Generally, kidney, small red, and white bean were more sensitive to tiafenacil than azuki bean. Dry bean injury was persistent and increased with time with the greatest injury observed 8 wk after emergence. Tiafenacil applied PRE can be a useful addition to the current strategies to control grass and broadleaf weeds, especially glyphosate-resistant horseweed and amaranth species prior to bean emergence.
The main result of this paper concerns the positivity of the Hodge bundles of abelian varieties over global function fields. As applications, we obtain some partial results on the Tate–Shafarevich group and the Tate conjecture of surfaces over finite fields.
Nutrition and the incidence of diseases during early life are considered environmental factors that determine people’s height when they become adults. While there is extensive literature focusing on the relationship between physical growth, general mortality and infant mortality rates, few studies analyse the impact of certain disease groups on the final height of historical populations. Using regional mortality rates by causes of death, the main objective of this study is to determine the onset of the disease environment during early life for populations born in Spain between 1916 and 1930, and its relationship with the stature reached at 21 years of age. A population-averaged model is performed on epidemic-infectious, gastrointestinal, and congenital diseases during the gestation period and first year of life. The disease burden in early life had a statistically significant negative effect on adult stature. These results support the premise that an improvement in the disease environment could lead to a greater number of short children surviving and therefore a decrease in the average height.
The policy of Universal Salt Iodisation (USI) could reduce population’s thyroid volume (TVOL) in iodine deficiency areas. Conversely, the improved growth and developmental status of children might increase the TVOL accordingly. Whether the decreased TVOL by USI conceals the increase effect of height and weight on TVOL is unclear. The aim of this study was to analyse the association between height, weight, iodine supplementation and TVOL. Five national Iodine Deficiency Disorder surveys were matched into four pairs according to the purpose of analysis. County-level data of both detected by paired surveys were incorporated; 1:1 random pairing method was used to match counties or individuals. The difference of TVOL between different height, weight, different iodine supplementation measures groups and the association between TVOL and them were studied. The mean height and weight of children aged 8–10 years increased from 129·9 cm and 26·9 kg in 2002 to 136·2 cm and 32·1 kg in 2019, while the median TVOL decreased from 3·10 ml to 2·61 ml. Iodine supplementation measures can affect TVOL; after excluding iodine effects, the median TVOL was increased with the height and weight. On the other side, after excluding the influence of height and weight, the median TVOL remained decreased. Only age, weight and salt iodine were significantly associated with TVOL in multiple linear models. Development of height and weight in children is the evidence of improved nutrition. The decreased TVOL caused by iodised salt measures conceals the increase effect of height and weight on TVOL. Age, weight and salt iodine affect TVOL significantly.
Let $X$ be a normal and geometrically integral projective variety over a global field $K$ and let $\bar {D}$ be an adelic ${\mathbb {R}}$-Cartier divisor on $X$. We prove a conjecture of Chen, showing that the essential minimum $\zeta _{\mathrm {ess}}(\bar {D})$ of $\bar {D}$ equals its asymptotic maximal slope under mild positivity assumptions. As an application, we see that $\zeta _{\mathrm {ess}}(\bar {D})$ can be read on the Okounkov body of the underlying divisor $D$ via the Boucksom–Chen concave transform. This gives a new interpretation of Zhang's inequalities on successive minima and a criterion for equality generalizing to arbitrary projective varieties a result of Burgos Gil, Philippon and Sombra concerning toric metrized divisors on toric varieties. When applied to a projective space $X = {\mathbb {P}}_K^{d}$, our main result has several applications to the study of successive minima of hermitian vector spaces. We obtain an absolute transference theorem with a linear upper bound, answering a question raised by Gaudron. We also give new comparisons between successive slopes and absolute minima, extending results of Gaudron and Rémond.
The role of anthropometric status on dengue is uncertain. We investigated the relations between anthropometric characteristics (height, body mass index and waist circumference (WC)) and two dengue outcomes, seropositivity and hospitalisation, in a cross-sectional study of 2038 children (aged 2–15 years) and 408 adults (aged 18–72 years) from Bucaramanga, Colombia. Anthropometric variables were standardised by age and sex in children. Seropositivity was determined through immunoglobulin G antibodies; past hospitalisation for dengue was self-reported. We modelled the prevalence of each outcome by levels of anthropometric exposures using generalised estimating equations with restricted cubic splines. In children, dengue seropositivity was 60.8%; 9.9% of seropositive children reported prior hospitalisation for dengue. WC was positively associated with seropositivity in girls (90th vs. 10th percentile adjusted prevalence ratio (APR) = 1.19; 95% confidence interval (CI) 1.03–1.36). Among adults, dengue seropositivity was 95.1%; 8.1% of seropositive adults reported past hospitalisation. Height was inversely associated with seropositivity (APR = 0.90; 95% CI 0.83–0.99) and with hospitalisation history (APR = 0.19; 95% CI 0.04–0.79). WC was inversely associated with seropositivity (APR = 0.89; 95% CI 0.81–0.98). We conclude that anthropometry correlates with a history of dengue, but could not determine causation. Prospective studies are warranted to enhance causal inference on these questions.
Anti-inflammatory agents such as long-chain n-3 fatty acids have been recognised to improve disease-related fatigue. We hypothesised that α-linolenic acid may also benefit in reduction of fatigue in low-grade inflammation such as overweight/obesity. Seventy-two healthy children and adolescents with BMI > 25 kg/m2 were randomised to flaxseed (n 38) and puffed wheat (n 34) groups. Participants consumed isoenergetic amounts of either 20 g/d flaxseed or 25 g/d puffed wheat for 4 weeks. Fatigue, mood feelings (depression, anxiety and stress), appetite, energy intake, weight, height and waist circumference were measured. Analysis was performed based on per-protocol and intention-to-treat (ITT) approaches. Consumption of flaxseed decreased mental fatigue and caused a significant between-group difference (P < 0·001). Although no significant change in physical and total score of fatigue was observed in either group, a significant between-group difference occurred due to a more remarkable change in these parameters in the flaxseed group. General fatigue, motivation, activity and mood feelings did not change significantly between groups. Flaxseed showed less benefit than puffed wheat on anthropometric measures as it caused a smaller increase in height (0·53 (sd 0·89) v. 1·09 (sd 0·87) cm, P = 0·03) and reduction in BMI (–0·25 (sd 0·63) v. −0·67 (sd 0·56) kg/m2, P = 0·01) than puffed wheat. Appetite and waist circumference decreased in both groups, but no significant difference was observed between groups. In ITT analysis, only alteration in mental fatigue was significant. In conclusion, consumption of flaxseed may improve mental fatigue in children with overweight/obesity. However, because of smaller increase in height, it is better to hinder administration of flaxseed during periods of growth.
To evaluate the association between the age of cow milk introduction and childhood growth.
Design:
A secondary analysis of a prospective cohort study.
Setting:
Toronto, Canada.
Participants:
Healthy children <5 years of age enrolled in the TARGet Kids! practice-based research network. The primary exposure was the age of cow milk introduction. The primary outcome was height-for-age z-score. Secondary outcomes were volume of cow milk consumed (cups/d) and BMI z-score. Outcomes were measured at the last visit before 5 years of age. Multiple linear regression was used to examine these relationships.
Results:
Among 1981 children, introduction of cow milk at a younger age was associated with greater height by 3–5 years of age (P < 0·001). Each month earlier that cow milk was introduced was associated with 0·03 higher height-for-age z-score unit (95 % CI –0·05, –0·02) or 0·1 cm (95 % CI –0·15, –0·12 cm). At 4 years of age, the height difference between a child introduced to cow milk at 9 v. 12 months was 0·4 cm (95 % CI –0·45, –0·35 cm). There was no association between the timing of cow milk introduction and volume of cow milk consumed per day or BMI z-score.
Conclusions:
Earlier introduction of cow milk was associated with greater height but not with weight status in children aged 3–5 years. Further research is needed to understand the casual relationship between earlier cow milk consumption and childhood height. These findings may be important for paediatricians and parents when considering when to introduce cow milk.
The aim of this study was to investigate the possible associations between depression, height and body mass index (BMI) in the adolescent and adult population of Penza city and oblast, Russia. The study included 554 adults aged 16–89 years. The presence and severity of depression was evaluated using Beck’s Depression Inventory (BDI-II). The participants self-reported their height (cm) and weight (kg) and these were used to calculate their BMI (kg/m2). Significant correlations were obtained between depression and short stature in young men, depression and short stature in participants with normal BMI and depression and age in overweight participants. Young women aged 16–23 years, and older men aged 60–89 years, presented the highest and very similar depression scores with no statistically significant difference between them. Special attention should be paid in Russia to these groups due to their higher risk of depressive disorders.
The classical twin design relies on a number of strong number of assumptions in order to yield unbiased estimates of heritability. This includes the equal environments assumption — that monozygotic and dizygotic twins experience similar degrees of environmental similarity — an assumption that is likely to be violated in practice for many traits of interest. An alternative method of estimating heritability that does not suffer from many of these limitations is to model trait similarity between sibling pairs as a function of their empirical genome-wide identity by descent sharing, estimated from genetic markers. In this review, I recount the story behind Nick Martin’s and my development of this method, our first attempts at applying it in a human population and more recent studies using the original and related methods to estimate trait heritability.
Preplant (PP) herbicide applications are an important tool within an integrated weed management system, specifically in no-till production. An understanding of crop tolerance regarding PP applications is important for effectively integrating a new herbicide into no-till cropping systems. Twelve field trials (six in corn and six in soybean) were conducted over a 2-yr period (2018 and 2019) near Exeter and Ridgetown, ON. The purpose of these studies was to evaluate the tolerance of soybean and corn to halauxifen-methyl applied PP, PRE, or POST at the registered rate (5 g a.i. ha−1) and twice the registered rate (10 g a.i. ha−1), hereafter referred to as the 1× and 2× rate, respectively. All trials were kept weed-free throughout the growing season to remove the confounding effect of weed interference. Halauxifen-methyl applied 14 d preplant (DPP), 7 DPP, 1 DPP, and 5 d after seeding (DAS) at the 1× and 2× rates caused ≤10% visible soybean injury. In contrast, halauxifen-methyl applied POST (cotyledon–unifoliate stage, VE-VC) caused 67% to 87% visible soybean injury, a 50% to 53% reduction in height, 65% to 81% decrease in population, 56% to 67% lower biomass, and 53% to 63% decline in yield. Halauxifen-methyl applied 10 DPP, 5 DPP, 1 DPP, 5 DAS, and POST (spike–one leaf stage, VE-V1) at the 1× and 2× rate caused ≤3% visible corn injury and caused no effect on corn height or biomass. Halauxifen-methyl applied at VE-V1 at the 2× rate reduced corn yield 10%. Based on these studies, the current application restriction of 7 DPP in soybean and 5 DPP in corn is conservative and could be expanded. Expanding the application window of halauxifen-methyl would increase the utility of this herbicide for producers.
Chile has experienced significant improvements in its economy; thus, a secular trend in height has been observed in its population. Gender equality has also improved hand in hand with active policies addressing the gender gap in several dimensions (work, education, health) and overall economic improvement. This study examined changes in sexual height dimorphism in four samples of Chilean male and female working-age subjects and attempted to establish associations with gender equality and welfare. Sexual height dimorphism was calculated and compared with gender equality and overall welfare indicators between 1955 and 1995. Sexual height dimorphism reduction was seen to be strongly associated with greater gender equality and some general welfare indicators, such as the infant mortality rate. Gross domestic product per capita was not associated with sexual height dimorphism, but it showed significant associations with gender equality indicators. Overall, the gender gap has been reduced in Chile, which can be observed through improvements in gender equality indicators and a reduction in height dimorphism, mainly in areas associated with women’s health. However, gender equality is still far behind in terms of female labour participation and women in political power, which require attention and further improvements.
This study explores the link between height and earnings, using data from the Russian Longitudinal Monitoring Survey for the year 2015 (24th wave). The dependent variable was average monthly income and the key independent variable was self-reported height, measured in centimetres. The empirical model also included a rich vector of personal and job-related factors that have been shown to be associated with earnings in the relevant literature. Sequential multiple regression and one-way analyses of variance (ANOVA) were used to analyse the data. The results suggest that height is a significant predictor of earnings in Russia. The results were found to be robust for a set of controls and tests.
A wide margin of crop safety is a desirable trait of POST herbicides, and investigation of crop tolerance is a key step in evaluation of new herbicides. Six field experiments were conducted in Ontario, Canada, from 2017 to 2018 to examine the influence of corn (Zea mays L.) hybrid (DKC42-60RIB, DKC43-47RIB, P0094AM, and P9840AM), application rate (1X and 2X), and application timing (PRE, V1, V3, and V5) on the tolerance of field corn to tolpyralate, a new 4-hydroxyphenyl pyruvate dioxygenase inhibitor, co-applied with atrazine. Two corn hybrids (DKC42-60RIB and DKC43-47RIB) exhibited slightly greater visible injury from tolpyralate + atrazine, applied POST, than P0094AM and P9840AM at 1 to 2 wk after application (WAA); hybrids responded similarly with respect to height, grain moisture, and yield. Applications of tolpyralate + atrazine at a 2X rate (80 + 2,000 g ai ha−1) induced greater injury (≤31.6%) than the field rate (40 + 1,000 g ha−1) (≤11.6%); the 2X rate applied at V1 or V3 decreased corn height and slightly increased grain moisture at harvest. On average, field rates resulted in marginally higher grain yields than 2X rates. Based on mixed-model multiple stepwise regression analysis, the air temperature at application, time of day, temperature range in the 24 h before application, and precipitation following application were useful predictor variables in estimating crop injury with tolpyralate + atrazine; however, additional environmental variables also affected crop injury. These results demonstrate the margin of corn tolerance with tolpyralate + atrazine, which provides a basis for optimization of application timing, rate, and corn hybrid selection to mitigate the risk of crop injury with this herbicide tank mixture.
The COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) project is a large international collaborative effort to analyze individual-level phenotype data from twins in multiple cohorts from different environments. The main objective is to study factors that modify genetic and environmental variation of height, body mass index (BMI, kg/m2) and size at birth, and additionally to address other research questions such as long-term consequences of birth size. The project started in 2013 and is open to all twin projects in the world having height and weight measures on twins with information on zygosity. Thus far, 54 twin projects from 24 countries have provided individual-level data. The CODATwins database includes 489,981 twin individuals (228,635 complete twin pairs). Since many twin cohorts have collected longitudinal data, there is a total of 1,049,785 height and weight observations. For many cohorts, we also have information on birth weight and length, own smoking behavior and own or parental education. We found that the heritability estimates of height and BMI systematically changed from infancy to old age. Remarkably, only minor differences in the heritability estimates were found across cultural–geographic regions, measurement time and birth cohort for height and BMI. In addition to genetic epidemiological studies, we looked at associations of height and BMI with education, birth weight and smoking status. Within-family analyses examined differences within same-sex and opposite-sex dizygotic twins in birth size and later development. The CODATwins project demonstrates the feasibility and value of international collaboration to address gene-by-exposure interactions that require large sample sizes and address the effects of different exposures across time, geographical regions and socioeconomic status.
Effective POST herbicides and herbicide mixtures are key components of integrated weed management in corn; however, herbicides vary in their efficacy based on application timing. Six field experiments were conducted over 2 yr (2017–2018) in southwestern Ontario, Canada, to determine the effects of herbicide application timing and rate on the efficacy of tolpyralate, a new 4-hydroxyphenyl pyruvate dioxygenase inhibitor. Tolpyralate at 15, 30, or 40 g ai ha−1 in combination with atrazine at 500 or 1,000 g ai ha−1 was applied PRE, early POST, mid-POST, or late POST. Tolpyralate + atrazine at rates ≥30 + 1,000 g ha−1 provided equivalent control of common lambsquarters and Powell amaranth applied PRE or POST, whereas no rate applied PRE controlled common ragweed, velvetleaf, barnyardgrass, or green foxtail. Common ragweed, common lambsquarters, velvetleaf, and Powell amaranth were controlled equally regardless of POST timing. In contrast, control of barnyardgrass and green foxtail declined when herbicide application was delayed to the late-POST timing, irrespective of herbicide rate. Similarly, corn grain yield declined within each tolpyralate + atrazine rate when herbicide applications were delayed to late-POST timing. Overall, the results of this study indicate that several monocot and dicot weed species can be controlled with tolpyralate + atrazine with an early to mid-POST herbicide application timing, before weeds reach 30 cm in height, and Powell amaranth and common lambsquarters can also be controlled PRE. Additionally, this study provides further evidence highlighting the importance of effective, early-season weed control in corn.