The May 2019 IPBES emphasised the scale of the current biodiversity crisis and the need for transformative change, but highlighted that the tools exist to enable this change. Conservation translocation is an increasingly used tool that involves people deliberately moving and releasing organisms where the primary goal is conservation – it includes species reintroductions, reinforcements, assisted colonisations and ecological replacements. It can be complex, expensive, time consuming, and sometimes controversial, but when best practice guidelines are followed it can be a very effective conservation method and a way of exciting and engaging people in environmental issues. Conservation translocations have an important role to play not only in improving the conservation status of individual species but also in ecological restoration and rewilding by moving keystone and other influential species. As the climate continues to change, species with poor dispersal abilities or opportunities will be at particular risk. Assisted colonisation, which involves moving species outside their indigenous range, is likely to become an increasingly used method. It is also a tool that may become increasingly used to avoid threats from the transmission of pathogens. Other more radical forms of conservation translocation, such as ecological replacements, multi-species conservation translocations, and the use of de-extinction and genetic interventions, are also likely to be given stronger consideration within the wider framework of ecological restoration. There have been significant advances in the science of reintroduction biology over the last three decades. However new ways of transferring and sharing such information are needed to enable a wider spectrum of practitioners to have easier access to knowledge and guidance. In the past the biological considerations of conservation translocations have often heavily outweighed the people considerations. However it is increasingly important that socio-economic factors are also built into projects and relevant experts involved to reduce conflict and improve the chances of success. Some level of biological and socio-economic risk will be present for most conservation translocations, but these can often be managed through the use of sensitivity, professionalism, and the application of tried and tested best practice. The role of species reintroduction and other forms of conservation translocations will be an increasingly important tool if we are to restore, and make more resilient, our damaged ecosystems.