A simple multiple-input-multiple-output (MIMO) antenna with quad-band-notched characteristics for ultra-wideband (UWB) system is proposed and tested in the article. Based on two similar radiators, the UWB-MIMO system only occupies 22 mm × 28 mm. By etching an inverted L-like meander slot, two inverted L-shaped slots, and adding a C-shaped stub beside the feeding line, four notched bands are realized (3.25–3.6, 5.05–5.48, 5.6–6, and 7.8–8.4 GHz) to suppress interference from WiMAX, lower WLAN, upper WLAN, and uplink of X-band satellite communication system. With a T-like stub extruding from the ground plane, port isolation is effectively improved. The results show that the antenna covers 3.1–10.6 GHz UWB frequency band except four rejected bands and has high isolation of better than −20 dB over most of the frequency band. Moreover, envelope correlation coefficient and good radiation patterns also prove that the introduced antenna is suitable for UWB applications.