The long- and finite-wavelength instabilities of weakly viscoelastic film on an oscillating inclined plane are investigated. By using the Chebyshev series solution with the Floquet theory, the combined effects of viscoelasticity and forcing amplitude on instability are described when the inclined plane oscillates in streamwise and wall-normal directions. For long-wavelength instability, the solution to the eigenvalue problem is obtained analytically by the asymptotic expansion method. Results show that the Floquet exponent is independent of the wall-normal oscillation amplitude. The effects of inclined angle, gravity and surface tension on the stability of viscoelastic liquid film are also discussed. For finite-wavelength instability, numerical results corresponding to the wall-normal oscillation disclose that with the increase of viscoelasticity, the unstable gravitational boundary moves to a higher wavenumber, and the critical amplitudes of subharmonic and harmonic instabilities are reduced. The neutral curve of gravity instability for streamwise oscillatory flow is divided into two parts, and a stable bandwidth is formed for a large value of the viscoelastic parameter. Besides, a new oscillatory mode is identified at small angles of inclination, which will be enhanced if the effect of viscoelasticity is incorporated.

Environmental exposures are known to be associated with pathogen transmission and immune impairment, but the association of exposures with aetiology and severity of community-acquired pneumonia (CAP) are unclear. A retrospective observational study was conducted at nine hospitals in eight provinces in China from 2014 to 2019. CAP patients were recruited according to inclusion criteria, and respiratory samples were screened for 33 respiratory pathogens using molecular test methods. Sociodemographic, environmental and clinical factors were used to analyze the association with pathogen detection and disease severity by logistic regression models combined with distributed lag nonlinear models. A total of 3323 CAP patients were included, with 709 (21.3%) having severe illness. 2064 (62.1%) patients were positive for at least one pathogen. More severe patients were found in positive group. After adjusting for confounders, particulate matter (PM) 2.5 and 8-h ozone (O3-8h) were significant association at specific lag periods with detection of influenza viruses and Klebsiella pneumoniae respectively. PM10 and carbon monoxide (CO) showed cumulative effect with severe CAP. Pollutants exposures, especially PM, O3-8h, and CO should be considered in pathogen detection and severity of CAP to improve the clinical aetiological and disease severity diagnosis.

In this paper, we have experimentally demonstrated a high-power and high-brightness narrow-linewidth fiber amplifier seeded by an optimized fiber oscillator. In order to improve the temporal stability, the fiber oscillator consists of a composite fiber Bragg grating-based cavity with an external feedback structure. By optimizing the forward and backward pumping ratio, the nonlinear effects and stimulated Raman scattering-induced mode distortion of the fiber amplifier are suppressed comprehensively, accompanied with the simultaneous improvement of beam quality and output power. The laser brightness is enhanced further by raising the threshold of transverse mode instability by approximately 1.0 kW by coiling the gain fiber with a novel curvature shape. Finally, a 6 kW narrow-linewidth laser is achieved with beam quality (M2) of approximately 1.4. The laser brightness doubled compared to the results before optimization. To the best of our knowledge, it is the highest brightness narrow-linewidth fiber laser based on a one-stage master oscillator power amplification structure.

Seed dormancy is an important trait associated with pre-sprouting and malting quality in barley. Genome-wide association studies (GWASs) have been used to detect quantitative trait loci (QTLs) underlying complex traits in major crops. In the present study, we collected 295 barley (Hordeum vulgare L.) accessions from Australia, Europe, Canada and China. A total of 25,179 single nucleotide polymorphism (SNP)/diversity arrays technology sequence markers were used for population structure, linkage disequilibrium and GWAS analysis. Candidate genes within QTL regions were investigated, and their expression levels were analysed using RNAseq data. Five QTLs for seed dormancy were identified. One QTL was mapped on chromosome 1H, and one QTL was mapped on chromosome 4H, while three QTLs were located on chromosome 5H. This is the first report of a QTL on the short arm of chromosome 5H in barley. Molecular markers linked to the QTL can be used for marker-assisted selection in barley breeding programmes.

In this study, we investigated the influence of fiber parameters on stimulated Raman scattering (SRS) and identified a unique pattern of SRS evolution in the counter tandem pumping configuration. Our findings revealed that the SRS threshold in counter-pumping is predominantly determined by the length of the output delivery fiber rather than the gain fiber. By employing the counter tandem pumping scheme and optimizing the fiber parameters, a 10 kW fiber laser was achieved with beam quality M2 of 1.92. No mode instability or severe SRS limitation was observed. To our knowledge, this study achieved the highest beam quality in over 10 kW fiber lasers based on conventional double-clad Yb-doped fiber.

The reconfigurable mechanisms can satisfy the requirements of changing environments, working conditions, and tasks on the function and performance of the mechanism and can be applied to machine tool manufacturing, space detection, etc. Inspired by the single-vertex fivefold origami pattern, a new reconfigurable parallel mechanism is proposed in this paper, which has special singular positions and stable motion due to replicating the stabilizing kinematic properties of origami. Through analyzing the topologic change of the folding process of the pattern and treating it as a reconfigurable joint, a new reconfigurable parallel mechanism with 3, 4, 5, or 6 degrees of freedom is obtained. Then, the kinematics solution, workspace, and singularity of the mechanism are calculated. The results indicate that the singular configuration of the origami-derived reconfigurable parallel mechanism is mainly located in a special plane, and the scope of the workspace is still large after the configuration change. The mechanism has the potential to adapt to multiple tasks and working conditions through the conversion among different configurations by folding reconfigurable joints on the branch chain.

Let $[a_1(x),a_2(x),a_3(x),\ldots ]$ be the continued fraction expansion of an irrational number $x\in [0,1)$. We are concerned with the asymptotic behaviour of the product of consecutive partial quotients of x. We prove that, for Lebesgue almost all $x\in [0,1)$,

$$ \begin{align*} \liminf_{n \to \infty} \frac{\log (a_n(x)a_{n+1}(x))}{\log n} = 0\quad \text{and}\quad \limsup_{n \to \infty} \frac{\log (a_n(x)a_{n+1}(x))}{\log n}=1. \end{align*} $$

We also study the Baire category and the Hausdorff dimension of the set of points for which the above liminf and limsup have other different values and similarly analyse the weighted product of consecutive partial quotients.

To overcome Yb lasing, a kilowatt-level 1535 nm fiber laser is utilized to in-band pump an Er:Yb co-doped fiber (EYDF) amplifier. The output power of a 301 W narrow-linewidth EYDF amplifier operating at 1585 nm, with 3 dB bandwidth of 150 pm and ${M}^2$< 1.4, is experimentally demonstrated. To the best of our knowledge, it is the highest output power achieved in L-band narrow-linewidth fiber amplifiers with good beam quality. Theoretically, a new ion transition behavior among energy levels for in-band pumping EYDF is uncovered, and a spatial-mode-resolved nonlinearity-assisted theoretical model is developed to understand its internal dynamics. Numerical simulations reveal that the reduction in slope efficiency is significantly related to excited-state absorption (ESA). ESA has a nonlinear hindering effect on power scaling. It can drastically lower the pump absorption and slope efficiency with increasing pump power for in-band pumped EYDF amplifiers. Meanwhile, optimized approaches are proposed to improve its power to the kilowatt level via in-band pumping.

Data on epidemiology trends of paediatric tuberculosis (TB) are limited in China. So, we investigated the clinical and epidemiological profiles in diagnosed TB disease and TB infection patients at Beijing Children’s Hospital. Of 3 193 patients, 51.05% had pulmonary TB (PTB) and 15.16% had extrapulmonary TB (EPTB). The most frequent forms of EPTB were TB meningitis (39.05%), pleural TB (29.75%), and disseminated TB (10.33%). PTB patients were significantly younger and associated with higher hospitalization frequency. Children aged 1–4 years exhibited higher risk of PTB and TB meningitis, and children aged 5–12 years had higher risk of EPTB. The proportion of PTB patients increased slightly from 40.9% in 2012 to 65% in 2019, and then decreased to 17.8% in 2021. The percentage of EPTB cases decreased from 18.3% in 2012 to 15.2% in 2019, but increased to 16.4% in 2021. Among EPTB cases, the largest increase was seen in TB meningitis. In conclusion, female and young children had higher risk of PTB in children. TB meningitis was the most frequent forms of EPTB among children, and young children were at high risk of TB meningitis. The distribution of different types of EPTB differed by age.

The Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), is the key vector insect transmitting the Candidatus Liberibacter asiaticus (CLas) bacterium that causes the devastating citrus greening disease (Huanglongbing, HLB) worldwide. The D. citri salivary glands (SG) exhibit an important barrier against the transmission of HLB pathogen. However, knowledge on the molecular mechanism of SG defence against CLas infection is still limited. In the present study, we compared the SG transcriptomic response of CLas-free and CLas-infected D. citri using an illumine paired-end RNA sequencing. In total of 861 differentially expressed genes (DEGs) in the SG upon CLas infection, including 202 upregulated DEGs and 659 downregulated DEGs were identified. Functional annotation analysis showed that most of the DEGs were associated with cellular processes, metabolic processes, and the immune response. Gene ontology and Kyoto Encyclopaedia of Genes and Genomes enrichment analyses revealed that these DEGs were enriched in pathways involving carbohydrate metabolism, amino acid metabolism, the immune system, the digestive system, the lysosome, and endocytosis. A total of 16 DEGs were randomly selected to further validate the accuracy of RNA-Seq dataset by reverse-transcription quantitative polymerase chain reaction. This study provides substantial transcriptomic information regarding the SG of D. citri in response to CLas infection, which may shed light on the molecular interaction between D. citri and CLas, and provides new ideas for the prevention and control of citrus psyllid.

The numerical investigation focuses on the flow patterns around a rectangular cylinder with three aspect ratios ($L/D=5$, $10$, $15$) at a Reynolds number of $1000$. The study delves into the dynamics of vortices, their associated frequencies, the evolution of the boundary layer and the decay of the wake. Kelvin–Helmholtz (KH) vortices originate from the leading edge (LE) shear layer and transform into hairpin vortices. Specifically, at $L/D=5$, three KH vortices merge into a single LE vortex. However, at $L/D=10$ and $15$, two KH vortices combine to form a LE vortex, with the rapid formation of hairpin vortex packets. A fractional harmonic arises due to feedback from the split LE shear layer moving upstream, triggering interaction with the reverse flow. Trailing edge (TE) vortices shed, creating a Kármán-like street in the wake. The intensity of wake oscillation at $L/D=5$ surpasses that in the other two cases. Boundary layer transition occurs after the saturation of disturbance energy for $L/D=10$ and $15$, but not for $L/D=5$. The low-frequency disturbances are selected to generate streaks inside the boundary layer. The TE vortex shedding induces the formation of a favourable pressure gradient, accelerating the flow and fostering boundary layer relaminarization. The self-similarity of the velocity defect is observed in all three wakes, accompanied by the decay of disturbance energy. Importantly, the decrease in the shedding frequency of LE (TE) vortices significantly contributes to the overall decay of disturbance energy. This comprehensive exploration provides insights into complex flow phenomena and their underlying dynamics.

The aim of this experiment was to investigate the differential proteomic characteristics of milk from high- and low-yielding Guanzhong dairy goats during the peak lactation period under the same feeding conditions. Nine Guanzhong dairy goats with high yield (H: 3.5 ± 0.17 kg/d) and nine with low yield (L:1.2 ± 0.25 kg/d) were selected for milk proteomic analysis using tandem mass tag technology. A total of 78 differentially expressed proteins were identified. Compared with L, 50 proteins including HK3, HSPB1 and ANXA2 were significantly upregulated in H milk, while 28 proteins including LALBA and XDH were significantly downregulated. Bioinformatics analysis of the differentially expressed proteins showed that galactose metabolism, purine metabolism, glycolysis/gluconeogenesis, MAPK signaling pathway, regulation of actin cytoskeleton and other pathways were closely related to milk yield. HK3, HSPB1, ANXA2, LALBA and XDH were important candidate proteins associated with the milk production characteristics of Guanzhong dairy goats. Our data provide relevant biomarkers and a theoretical basis for improving milk production in Guanzhong dairy goats.

The Righi–Leduc heat flux generated by the self-generated magnetic field in the ablative Rayleigh–Taylor instability driven by a laser irradiating thin targets is studied through two-dimensional extended-magnetohydrodynamic simulations. The perturbation structure gets into a low magnetization state though the peak strength of the self-generated magnetic field could reach hundreds of teslas. The Righi–Leduc effect plays an essential impact both in the linear and nonlinear stages, and it deflects the total heat flux towards the spike base. Compared to the case without the self-generated magnetic field included, less heat flux is concentrated at the spike tip, finally mitigating the ablative stabilization and leading to an increase in the velocity of the spike tip. It is shown that the linear growth rate is increased by about 10% and the amplitude during the nonlinear stage is increased by even more than 10% due to the feedback of the magnetic field, respectively. Our results reveal the importance of Righi–Leduc heat flux to the growth of the instability and promote deep understanding of the instability evolution together with the self-generated magnetic field, especially during the acceleration stage in inertial confinement fusion.

LongYan kaolin has a large Fe content which affects the coloring. Bioleaching treatments to remove Fe impurities were conducted here using indigenous dissimilatory Fe(III)-reducing bacteria. The factors that affect bioleaching efficiency include bioleaching time, carbon source, pH, temperature, pulp density, and inoculum density and these were examined. Environmental scanning electron microscopy and X-ray diffraction were used to examine any textural or mineralogical changes at the surface of the kaolin that may have occurred during the bioleaching. Iron impurities in the kaolin were reduced from 0.88% to 0.48% with an increase in the natural whiteness index from 60.8% to 81.5% after 7 days of bioleaching treatment. A granulometric analysis of dispersed kaolin demonstrated that the bioleaching resulted in a decrease in particle size. The results demonstrated that the bioleaching was very effective at improving the quality of the kaolin, where insoluble Fe(III), either adsorbed to the kaolin surfaces or admixed as amorphous forms, was leached out by micro-organisms as water-soluble Fe(II).

Graphite phase carbon nitride (g-C3N4) is a non-metal semiconductor material with a suitable band gap (2.7 eV) for visible photocatalysis. However, the high cost of relevant synthesis methods and poor adsorption performance have limited its practical applications. The objective of the present study was to mitigate these problems by synthesizing the g-C3N4 in the presence of exfoliated montmorillonite (Mnt). Compared with bulk montmorillonite, the specific surface area of exfoliated two-dimensional Mnt layers was significantly increased. As a result, the light transmittance of the lamella improved noticeably due to the fact that a freshly exposed surface had a large number of active reaction sites, making Mnt an excellent carrier for the photocatalyst g-C3N4. In order to improve the photocatalytic performance of g-C3N4, a series of g-C3N4/Mnt composites was prepared by a wet chemical method using Mnt nanolayers as the matrix. X-ray diffraction, infrared spectroscopy, Brunauer-Emmett-Teller nitrogen adsorption/desorption, transmission electron microscopy, and ultraviolet-visible diffuse reflectance spectroscopy were used to analyze the phase structure, the chemical bonds, the specific surface area and pore sizes, the morphology, and the light absorption characteristics of the composites, respectively. Rhodamine B (RhB) served as the target dye to test the photocatalytic degradation performance of the composites under visible light. According to the findings, the surface of the Mnt nanolayers was densely and uniformly covered by g-C3N4, forming a multi-layered stack structure. An increase of the calcination temperature improved the crystallinity of g-C3N4, leading first to densification and then to relaxation of the layered composite structure. Conversely, the band gap of the composite gradually decreased from 2.56 to 2.4 eV. Furthermore, temperature exposure changed the photocatalytic performance of the composite drastically. While the largest photocatalytic activity was observed at 610°C, it started to decrease with further heating of the composite. The complete degradation of RhB solution occurred after 2 h of visible light irradiation. The findings of the current study provide a scientific basis for the synthesis of a new generation of photocatalysts.

Foilless diode are widely used in high-power microwave devices, but the traditional foilless diodes have large volume, heavy weight, and high power consumption, which are not conducive to the application of high-power microwave system on mobile platform. In order to reduce the size of the foilless diode, improve the transmission efficiency of electron beams, and reduce the weight and power consumption of the guiding magnetic field system, an axial foilless diode with a composite guiding magnetic field system is developed in this paper. By adjusting the structure size and magnetic field parameters of solenoid coil, permanent magnet, and soft magnet, the configuration of the composite magnetic field is optimized. The diameter of the anode tube is about 40% smaller than that of the original structure, and the weight and power consumption of the guiding magnetic system are about 40% lower than that of the original system when the same axial magnetic field intensity in the uniform region is generated. When the magnetic field strength of the permanent magnet is set as 1.4 T and that of the solenoid coil is in the range of 0.5 T∼1 T, the electron beam transmission efficiency is 100%, and the diode impedance is adjustable in the range of 100 Ω∼240 Ω. The experimental results verify the correctness of the simulation analysis. The experimental results show that when the magnetic field strength of the solenoid coil is 0.98 T (0.5 T) and that of the permanent magnet is 1.4 T, the transmission efficiency of the high-current annular electron beam with a peak voltage of 636 kV (590 kV) and a peak current of 3.3 kA (2.6 kA) is 100%, and the diode impedance is about 194 Ω (220 Ω).

In spite of many studies of laterite origins in various parts of the world, the origin of laterite in the middle to lower reaches of the Yangtze River is still a topic of debate, thus leaving doubts about the prevailing environmental and climatic conditions at the time. The purpose of this study was to provide greater understanding of this subject by examining in more detail the associated mineralogical evolution, i.e. clay mineral composition, structural characteristics of clays in various beds with different degrees of weathering along the laterite profile, and the alteration mechanisms during the pedogenic process in tropical to semitropical climate conditions. High-resolution transmission electron microscopy (HTEM), X-ray diffraction, and wavelength dispersive X-ray fluorescence spectrometry were used to characterize the samples in order to link clay mineralogy in various beds with different degrees of weathering along the laterite profile to the formation and origin of laterites in the region. The laterite profile displayed a distinct layered structure and was divided into a saprolite (B4), a light colored net-like clay bed (B3), a brown-red gravelly clay bed (B2), and a dark-brown topsoil (B1), respectively, from bottom to top. The clay mineral assemblage of beds B1 and B2 was illite, kaolinite, and chlorite, while that of beds B3 and B4 was mainly kaolinite with minor illite. The bimodal particle-size distribution of clay minerals in the laterite profile indicated that fine-grained particles could have been produced by partial dissolution and decomposition of coarse-grained ones. Examination by HRTEM revealed that fine-grained particles usually occurred as X-ray amorphous materials in the upper soil beds, but with euhedral morphology in the lower portions, suggesting that the fine-grained particles in the lower soil beds might be partially neoformed during the weathering process. Amorphous spots occurred frequently in kaolinite crystals in the upper soil beds, while the structure of kaolinite was well preserved, with a well defined lattice-fringe image. The illite crystallinity index exhibited a trend of downward decrease, while the values of the chemical index of alteration (CIA = Al2O3/(Al2O3+ CaO+ K2O+ Na2O) × 100%) of the soil profile showed a trend of downward increase. Samples of the upper soil beds, B1 and B2, had comparable SiO2/Al2O3 ratios of 5.37–6.22, while those of the lower beds, B3 and B4, had significantly smaller SiO2/Al2O3 ratios of 1.92–3.98, suggesting that the latter had a greater degree of weathering than the former, in reasonable agreement with the results of the illite crystallinity and CIA index. In addition, samples from B1 and B2 had similar TiO2/Al2O3 ratios of 0.042–0.053, while those from B3 and B4 had comparable TiO2/Al2O3 ratios of 0.021–0.033, comparable to the value 0.020 of the bedrock, and were notably smaller than the upper soil beds, indicating that materials of the upper soil beds, B1 and B2, had a different origin from the lower soil beds. The upper bed was probably derived from eolian accumulation due to intensification of the winter monsoon and aridity in central Asia and was modified by intense chemical weathering since the late Pleistocene, while the lower bed originated from an in situ weathering of the underlying argillaceous limestone.

In order to establish a compact all-optical Thomson scattering source, experimental studies were conducted on the 45 TW Ti: sapphire laser facility. By including a steel wafer, mixed gas, and plasma mirror into a double-exit jet, several mechanisms, such as shock-assisted ionization injection, ionization injection, and driving laser reflection, were integrated into one source. So, the source of complexity was remarkably reduced. Electron bunches with central energy fluctuating from 90 to 160 MeV can be produced. Plasma mirrors were used to reflect the driving laser. The scattering of the reflected laser on the electron bunches led to the generation of X-ray photons. Through comparing the X-ray spots under different experimental conditions, it is confirmed that the X-ray photons are generated by Thomson scattering. For further application, the energy spectra and source size of the Thomson scattering source were measured. The unfolded spectrum contains a large amount of low-energy photons besides a peak near 67 keV. Through importing the electron energy spectrum into the Monte Carlo simulation code, the different contributions of the photons with small and large emitting angles can be used to explain the origin of the unfolded spectrum. The maximum photon energy extended to about 500 keV. The total photon production was 107/pulse. The FWHM source size was about 12 μm.

The poor environmental stability of natural anthocyanin hinders its usefulness in various functional applications. The objectives of the present study were to enhance the environmental stability of anthocyanin extracted from Lycium ruthenicum by mixing it with montmorillonite to form an organic/inorganic hybrid pigment, and then to synthesize allochroic biodegradable composite films by incorporating the hybrid pigment into sodium alginate and test them for potential applications in food testing and packaging. The results of X-ray diffraction, Fourier-transform infrared spectroscopy, and use of the Brunauer–Emmett–Teller method and zeta potential demonstrated that anthocyanin was both adsorbed on the surface and intercalated into the interlayer of montmorillonite via host–guest interaction, and the hybrid pigments obtained allowed good, reversible, acid/base behavior after exposure to HCl and NH3 atmospheres. The composite films containing hybrid pigments had good mechanical properties due to the uniform dispersion of the pigments in a sodium alginate substrate and the formation of hydrogen bonds between them. Interestingly, the composite films also exhibited reversible acidichromism. The as-prepared hybrid pigments in composite films could, therefore, serve simultaneously as a reinforced material and as a smart coloring agent for a polymer substrate.